Mutant FLT3: A Direct Target of Sorafenib in Acute Myelogenous Leukemia von Zhang, Weiguo, Konopleva, Marina, Shi, Yue-xi, McQueen, Teresa, Harris, David, Ling, Xiaoyang, Estrov, Zeev, Quintás-Cardama, Alfonso, Small, Donald, Cortes, Jorge, Andreeff, Michael

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML von Zeng, Zhihong, Xi Shi, Yue, Samudio, Ismael J., Wang, Rui-Yu, Ling, Xiaoyang, Frolova, Olga, Levis, Mark, Rubin, Joshua B., Negrin, Robert R., Estey, Elihu H., Konoplev, Sergej, Andreeff, Michael, Konopleva, Marina

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Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment von Chen, Ye, Jacamo, Rodrigo, Shi, Yue-xi, Wang, Rui-yu, Battula, Venkata Lokesh, Konoplev, Sergej, Strunk, Dirk, Hofmann, Nicole A., Reinisch, Andreas, Konopleva, Marina, Andreeff, Michael

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia von Konopleva, Marina, Contractor, Rooha, Tsao, Twee, Samudio, Ismael, Ruvolo, Peter P., Kitada, Shinichi, Deng, Xingming, Zhai, Dayong, Shi, Yue-Xi, Sneed, Thomas, Verhaegen, Monique, Soengas, Maria, Ruvolo, Vivian R., McQueen, Teresa, Schober, Wendy D., Watt, Julie C., Jiffar, Tilahun, Ling, Xiaoyang, Marini, Frank C., Harris, David, Dietrich, Martin, Estrov, Zeev, McCubrey, James, May, W. Stratford, Reed, John C., Andreeff, Michael

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo von FUEYO, J, GOMEZ-MANZANO, C, ALEMANY, R, LEE, P. S. Y, MCDONNELL, T. J, MITLIANGA, P, SHI, Y.-X, LEVIN, V. A, YUNG, W. K. A, KYRITSIS, A. P

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Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells von Konopleva, Marina, Zhang, Weiguo, Shi, Yue-Xi, McQueen, Teresa, Tsao, Twee, Abdelrahim, Maen, Munsell, Mark F, Johansen, Mary, Yu, Dihua, Madden, Timothy, Safe, Stephen H, Hung, Mien-Chie, Andreeff, Michael

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PAX6 suppresses growth of human glioblastoma cells von ZHOU, Yi-Hong, XIAOSONG WU, YUNG, W. K, FANG TAN, SHI, Yue-Xi, GLASS, Tricia, LIU, T. J, WATHEN, Kyle, HESS, Kenneth R, GUMIN, Joy, LANG, Frederick

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Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment von Zeng, Zhihong, Shi, Yue Xi, Tsao, Twee, Qiu, YiHua, Kornblau, Steven M., Baggerly, Keith A., Liu, Wenbin, Jessen, Katti, Liu, Yi, Kantarjian, Hagop, Rommel, Christian, Fruman, David A., Andreeff, Michael, Konopleva, Marina

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Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models von Benito, Juliana, Ramirez, Marc S, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine G, Lu, Hongbo, Shi, Yue-Xi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip K, Marszalek, Joseph R, Davis, R Eric, Bankson, James A, Cortes, Jorge E, Hart, Charles P, Andreeff, Michael, Konopleva, Marina

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TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment von Tabe, Yoko, Shi, Yue Xi, Zeng, Zhihong, Jin, Linhua, Shikami, Masato, Hatanaka, Yasuhito, Miida, Takashi, Hsu, Frank J, Andreeff, Michael, Konopleva, Marina

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2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer von Samudio, Ismael, Konopleva, Marina, Hail, Numsen, Shi, Yue-Xi, McQueen, Teresa, Hsu, Timothy, Evans, Randall, Honda, Tadashi, Gribble, Gordon W., Sporn, Michael, Gilbert, Hiram F., Safe, Stephen, Andreeff, Michael

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The Relevance of Cell Proliferation, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor Production to Angiogenesis and Tumorigenicity in Human Glioma Cell Lines von LI DAO KE, SHI, Y.-X, IM, S.-A, XIASHAN CHEN, YUNG, W. K. A

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VEGF121, VEGF165 overexpression enhances tumorigenicity in U251 MG but not in NG-1 glioma cells von LI DAO KE, SHI, Yue-Xi, YUNG, W. K

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Current Situation of International Organization for Standardization/Technical Committee 249 International Standards of Traditional Chinese Medicine von Liu, Yu-qi, Wang, Yue-xi, Shi, Nan-nan, Han, Xue-jie, Lu, Ai-ping

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Abstract LB-95: Inhibition of CXCR4/Stat3 signaling by AMD3465 exerts major tumor- and metastasis-suppressive effects in syngenic 4T1 breast cancer model von Ling, Xiaoyang, Spaeth, Erika L., Shi, Yue-xi, Konopleva, Marina

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Abstract 2971: Human extramedullary bone and bone marrow in mice: First in vivo model of a genetically controlled hematopoietic environment - Role of CTGF and HIF1-α von Andreeff, Michael, Chen, Ye, Battula, Venkata Lokesh, Hofmann, Nicole A., Reinisch, Andreas, Shi, Yue Xi, Wang, Rui Yu, Konoplev, Sergej, Strunk, Dirk, Konopleva, Marina

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Correction: Corrigendum von Fueyo, Juàn, Gomez-Manzano, Candelaria, Alemany, Ramon, Lee, Polly SN, McDonnell, Timothy J, Mitlianga, Paraskevi, Shi, Yue-Xi, Levin, V A, Yung, WK Alfred, Kyritsis, Athanassios P

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Human Extramedullary Bone and Bone Marrow in Mice: First In Vivo Model of a Genetically Controlled Hematopoietic Environment von Chen, Ye, Jacamo, Rodrigo O, Hofmann, Nicole A., Shi, Yue-xi, Wang, Rui-yu, Konoplev, Sergej, Strunk, Dirk, Konopleva, Marina, Andreeff, Michael

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Mesenchymal Stem Cells From Patients with Acute Myeloid Leukemia (AML) Can Differentiate Into B-Cells in NOD/SCID/IL-2Rγ-/- Mice von Wang, Rui-Yu, Shi, Yue-Xi, Zeng, Zhihong, Schober, Wendy D., McQueen, Teresa J., Hopwood, Vicki L., Korchin, Borys, Konopleva, Marina, Andreeff, Michael

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Therapeutic Targeting of the Hypoxic Microenvironment in Acute Lymphocytic Leukemia von Konopleva, Marina, Benito, Juliana, Shi, Yue-Xi, Konoplev, Sergej, Kornblau, Steven M., Frolova, Olga, Zweidler-McKay, Patrick A., Qiu, YiHua, Wilson, William R., Campana, Dario, Jacamo, Rodrigo, Lu, Hongbo, Fang, Wendy, Borthakur, Gautam, Bueso-Ramos, Carlos E., Kantarjian, Hagop M., Thomas, Deborah A., Andreeff, Michael

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