Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma von Zhuang, Junling, Shirazi, Fazal, Singh, Ram Kumar, Kuiatse, Isere, Wang, Hua, Lee, Hans C., Berkova, Zuzana, Berger, Allison, Hyer, Marc, Chattopadhyay, Nibedita, Syed, Sakeena, Shi, Judy Qiuju, Yu, Jie, Shinde, Vaishali, Tirrell, Stephen, Jones, Richard Julian, Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.

Volltext

Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy von Sato, Yosuke, Casson, Cierra N., Matsuda, Atsushi, Kim, James I., Shi, Judy Qiuju, Iwasaki, Shinji, Chen, Susan, Modrell, Brett, Chan, Chingkit, Tavares, Daniel, Austen, Douglas, Ida, Koh, Tayber, Olga, Hein, Pyae, Comeau, Robert, Lin, Yafang, Shaw, Michael H.

Volltext

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905) von Duffey, Matthew O, Vos, Tricia J, Adams, Ruth, Alley, Jennifer, Anthony, Justin, Barrett, Cynthia, Bharathan, Indu, Bowman, Douglas, Bump, Nancy J, Chau, Ryan, Cullis, Courtney, Driscoll, Denise L, Elder, Amy, Forsyth, Nancy, Frazer, Jonathan, Guo, Jianping, Guo, Luyi, Hyer, Marc L, Janowick, David, Kulkarni, Bheemashankar, Lai, Su-Jen, Lasky, Kerri, Li, Gang, Li, Jing, Liao, Debra, Little, Jeremy, Peng, Bo, Qian, Mark G, Reynolds, Dominic J, Rezaei, Mansoureh, Scott, Margaret Porter, Sells, Todd B, Shinde, Vaishali, Shi, Qiuju Judy, Sintchak, Michael D, Soucy, Francois, Sprott, Kevin T, Stroud, Stephen G, Nestor, Michelle, Visiers, Irache, Weatherhead, Gabriel, Ye, Yingchun, D’Amore, Natalie

Volltext

The Anti-Tumor Effect of the Ubiquitin-Activating Enzyme (UAE) Inhibitor TAK-243 on Pre-Clinical Models of Multiple Myeloma von Zhuang, Junling, Lee, Hans, Kuiatse, Isere, Wang, Hua, Shirazi, Fazal, Berger, Allison, Hyer, Marc, Chattopadhyay, Nibedita, Syed, Sakeena, Shi, Judy Qiuju, Yu, Jie, Shinde, Vaishali, Kreshock, Anna, Tirrell, Stephen, Menon, Saurabh, Jones, Richard Julian, Orlowski, Robert Z.

Volltext

Abstract 3719: TAK-243, a small molecule inhibitor of the ubiquitin activating enzyme (UAE), disrupts DNA damage repair and sensitizes tumor cells and xenografts to ionizing radiat... von Milhollen, Michael A., Shi, Judy Qiuju, Traore, Tary, Huck, Jessica, Sappal, Darshan, Iwai, Kenichi, Ohashi, Akihiro, Rabino, Claudia, Duffy, Jennifer A., Lightcap, Eric, Ishii, Yuko, Ciavarri, Jeffrey, Bence, Neil, Berger, Allison J., Hyer, Marc L.

Volltext

ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND CHEMOTHERAPEUTIC AGENTS von HUCK, Jessica, HYER, Marc, BENCE, Neil, MILHOLLEN, Michael, TRAORE, Tary, SHI, Judy Qiuju

Volltext bestellen

ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND CHEMOTHERAPEUTIC AGENTS von HUCK, Jessica, HYER, Marc, BENCE, Neil, MILHOLLEN, Michael, TRAORE, Tary, SHI, Judy Qiuju

Volltext bestellen

ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND CHEMOTHERAPEUTIC AGENTS von HUCK, Jessica, HYER, Marc, BENCE, Neil, MILHOLLEN, Michael, TRAORE, Tary, SHI, Judy Qiuju

Volltext bestellen

ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND CHEMOTHERAPEUTIC AGENTS von BENCE, NEIL, MILHOLLEN, MICHAEL, HUCK, JESSICA, HYER, MARC, SHI, JUDY, QIUJU, TRAORE, TARY

Volltext bestellen

Administration of ubiquitin-activating enzyme inhibitor and chemotherapeutic agents von BENCE, NEIL, MILHOLLEN, MICHAEL, HUCK, JESSICA, HYER, MARC, SHI, JUDY QIUJU, TRAORE, TARY

Volltext bestellen