Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa von Bricio-Moreno, Laura, Sheridan, Victoria H., Goodhead, Ian, Armstrong, Stuart, Wong, Janet K.L., Waters, Elaine M., Sarsby, Joscelyn, Panagiotou, Stavros, Dunn, James, Chakraborty, Adrita, Fang, Yongliang, Griswold, Karl E., Winstanley, Craig, Fothergill, Joanne L., Kadioglu, Aras, Neill, Daniel R.

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Evolutionary trade-offs associated with loss of pmrb function in host-adapted pseudomonas aeruginosa von Bricio-Moreno, Laura, Sheridan, Victoria H, Goodhead, Ian, Armstrong, Stuart, Wong, Janet K.L, Waters, Elaine M, Sarsby, Joscelyn, Panagiotou, Stavros, Dunn, James, Chakraborty, Adrita, Fang, Yongliang, Griswold, Karl E, Winstanley, Craig, Fothergill, Joanne L, Kadioglu, Aras, Neill, Daniel R

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Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine von Heath, Paul T, Galiza, Eva P, Baxter, David N, Boffito, Marta, Browne, Duncan, Burns, Fiona, Chadwick, David R, Clark, Rebecca, Cosgrove, Catherine, Galloway, James, Goodman, Anna L, Heer, Amardeep, Higham, Andrew, Iyengar, Shalini, Jamal, Arham, Jeanes, Christopher, Kalra, Philip A, Kyriakidou, Christina, McAuley, Daniel F, Meyrick, Agnieszka, Minassian, Angela M, Minton, Jane, Moore, Patrick, Munsoor, Imrozia, Nicholls, Helen, Osanlou, Orod, Packham, Jonathan, Pretswell, Carol H, San Francisco Ramos, Alberto, Saralaya, Dinesh, Sheridan, Ray P, Smith, Richard, Soiza, Roy L, Swift, Pauline A, Thomson, Emma C, Turner, Jeremy, Viljoen, Marianne E, Albert, Gary, Cho, Iksung, Dubovsky, Filip, Glenn, Greg, Rivers, Joy, Robertson, Andreana, Smith, Kathy, Toback, Seth

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CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms von Panizzi, Jennifer R, Becker-Heck, Anita, Castleman, Victoria H, Al-Mutairi, Dalal A, Liu, Yan, Loges, Niki T, Pathak, Narendra, Austin-Tse, Christina, Sheridan, Eamonn, Schmidts, Miriam, Olbrich, Heike, Werner, Claudius, Häffner, Karsten, Hellman, Nathan, Chodhari, Rahul, Gupta, Amar, Kramer-Zucker, Albrecht, Olale, Felix, Burdine, Rebecca D, Schier, Alexander F, O'Callaghan, Christopher, Chung, Eddie M K, Reinhardt, Richard, Mitchison, Hannah M, King, Stephen M, Omran, Heymut, Drummond, Iain A

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Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy von Du Toit, George, Roberts, Graham, Sayre, Peter H, Bahnson, Henry T, Radulovic, Suzana, Santos, Alexandra F, Brough, Helen A, Phippard, Deborah, Basting, Monica, Feeney, Mary, Turcanu, Victor, Sever, Michelle L, Gomez Lorenzo, Margarita, Plaut, Marshall, Lack, Gideon

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First-in-Human Phase I Study of ABBV-838, an Antibody-Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma von Vij, Ravi, Nath, Rajneesh, Afar, Daniel E H, Mateos, María-Victoria, Berdeja, Jesús G, Raab, Marc S, Guenther, Andreas, Martínez-López, Joaquín, Jakubowiak, Andrzej J, Leleu, Xavier, Weisel, Katja, Wong, Shekman, Gulbranson, Scott, Sheridan, James P, Reddy, Anita, Paiva, Bruno, Singhal, Anil, San-Miguel, Jesús F, Moreau, Philippe

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Effect of Avoidance on Peanut Allergy after Early Peanut Consumption von Du Toit, George, Sayre, Peter H, Roberts, Graham, Sever, Michelle L, Lawson, Kaitie, Bahnson, Henry T, Brough, Helen A, Santos, Alexandra F, Harris, Kristina M, Radulovic, Suzana, Basting, Monica, Turcanu, Victor, Plaut, Marshall, Lack, Gideon

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Evidence for 28 genetic disorders discovered by combining healthcare and research data von Kaplanis, Joanna, Samocha, Kaitlin E., Wiel, Laurens, Zhang, Zhancheng, Arvai, Kevin J., Eberhardt, Ruth Y., Gallone, Giuseppe, Lelieveld, Stefan H., Martin, Hilary C., McRae, Jeremy F., Short, Patrick J., Torene, Rebecca I., de Boer, Elke, Danecek, Petr, Gardner, Eugene J., Huang, Ni, Lord, Jenny, Martincorena, Iñigo, Pfundt, Rolph, Reijnders, Margot R. F., Yeung, Alison, Yntema, Helger G., Vissers, Lisenka E. L. M., Juusola, Jane, Wright, Caroline F., Brunner, Han G., Firth, Helen V., FitzPatrick, David R., Barrett, Jeffrey C., Hurles, Matthew E., Gilissen, Christian, Retterer, Kyle

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Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort von du Toit, George, Sayre, Peter H., Roberts, Graham, Lawson, Kaitie, Sever, Michelle L., Bahnson, Henry T., Fisher, Helen R., Feeney, Mary, Radulovic, Suzana, Basting, Monica, Plaut, Marshall, Lack, Gideon, Chan, Susan, Fox, Adam, Abraham, Mable, Adam, Muhsinah, Coverdale, Louise, Duncan, Claire, Nixon, Amy, O’Dwyer-Leeson, Una, Offord, Victoria, Sheridan, Aine, Watson, Fiona, Witham, Natalie, Cockerell, Kathryn, Harland, Gail, Miller, Tiffany, Stedman, Charlotte, Clarke, Catherine, Cleaver, Richard, Deutsch, Gemma, Parr, Alicia, Becares, Natalia, Crossley, Matthew, Francisco, Natalia do Couto, Richards, Kerry, Pietraszewicz, Ewa, Stephens, Alick, Sudra, Asha, Wester, Rianne, Wilson, Alastair, Wu, Celine, Heath, Jenna, Hersee, Kathryn, Patkunam, Devi, Asare, Adam, Chani, Eduard, Evind, Judith, Lim, Noha, Plough, Audrey, Lorenzo, Margarita Gomez, Panza, Joy Laurienzo, Johnson, Jackie, Hu, Jack, Mason, Travis

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Feasibility of pharmacy-based research opportunity to enhance community testing and surveillance von Venditto, Vincent J., Hudspeth, Brooke, Freeman, Patricia R., Qasrawi, Lien, Guy, R. Kiplin, Farley, Victoria H., Johnson, Royce A., Freeman, Edward, Henson, David, Marion, Ryan, Wagner, Sheridan B., Doratt, Brianna M., Messaoudi-Powers, Ilhem

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Regulation of metabolic health by dietary histidine in mice von Flores, Victoria, Spicer, Alexandra B., Sonsalla, Michelle M., Richardson, Nicole E., Yu, Deyang, Sheridan, Grace E., Trautman, Michaela E., Babygirija, Reji, Cheng, Eunhae P., Rojas, Jennifer M., Yang, Shany E., Wakai, Matthew H., Hubbell, Ryan, Kasza, Ildiko, Tomasiewicz, Jay L., Green, Cara L., Dantoin, Claudia, Alexander, Caroline M., Baur, Joseph A., Malecki, Kristen C., Lamming, Dudley W.

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas von Palles, Claire, Cazier, Jean-Baptiste, Howarth, Kimberley M, Domingo, Enric, Jones, Angela M, Broderick, Peter, Kemp, Zoe, Spain, Sarah L, Guarino, Estrella, Salguero, Israel, Sherborne, Amy, Chubb, Daniel, Carvajal-Carmona, Luis G, Ma, Yusanne, Kaur, Kulvinder, Dobbins, Sara, Barclay, Ella, Gorman, Maggie, Martin, Lynn, Kovac, Michal B, Humphray, Sean, Lucassen, Anneke, Holmes, Christopher C, Bentley, David, Donnelly, Peter, Taylor, Jenny, Petridis, Christos, Roylance, Rebecca, Sawyer, Elinor J, Kerr, David J, Clark, Susan, Grimes, Jonathan, Kearsey, Stephen E, Thomas, Huw J W, McVean, Gilean, Houlston, Richard S, Tomlinson, Ian

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Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity von Tsilochristou, Olympia, du Toit, George, Sayre, Peter H., Roberts, Graham, Lawson, Kaitie, Sever, Michelle L., Bahnson, Henry T., Radulovic, Suzana, Basting, Monica, Plaut, Marshall, Lack, Gideon, Chan, Susan, Fox, Adam, Fisher, Helen, Abraham, Mable, Adam, Muhsinah, Coverdale, Louise, Duncan, Claire, Nixon, Amy, O'Dwyer-Leeson, Una, Offord, Victoria, Sheridan, Aine, Watson, Fiona, Witham, Natalie, Cockerell, Kathryn, Harland, Gail, Miller, Tiffany, Stedman, Charlotte, Clarke, Catherine, Cleaver, Richard, Deutsch, Gemma, Parr, Alicia, Becares, Natalia, Crossley, Matthew, Francisco, Natalia do Couto, Richards, Kerry, Pietraszewicz, Ewa, Stephens, Alick, Sudra, Asha, Wester, Rianne, Wilson, Alastair, Wu, Celine, Heath, Jenna, Hersee, Kathryn, Patkunam, Devi, Asare, Adam, Chani, Eduard, Evind, Judith, Lim, Noha, Plough, Audrey, Whitehouse, Don, Lorenzo, Margarita Gomez, Panza, Joy Laurienzo, Lussier, Stephanie, Hu, Jack, Mason, Travis

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Identifying infants at high risk of peanut allergy: The Learning Early About Peanut Allergy (LEAP) screening study von Du Toit, George, MBBCh, FRCPCH, Roberts, Graham, MD, Sayre, Peter H., MD, PhD, Plaut, Marshall, MD, Bahnson, Henry T., MPH, Mitchell, Herman, PhD, Radulovic, Suzana, MD, Chan, Susan, MD, Fox, Adam, MD, Turcanu, Victor, MD, Lack, Gideon, MD, FRCPCH

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Functional genomics and metabolomics advance the ethnobotany of the Samoan traditional medicine “matalafi” von Molimau-Samasoni, Seeseei, Woolner, Victoria Helen, Foliga, Su’emalo Talie, Robichon, Katharina, Patel, Vimal, Andreassend, Sarah K., Sheridan, Jeffrey P., Kawa, Tama Te, Gresham, David, Miller, Darach, Sinclair, Daniel J., La Flamme, Anne C., Melnik, Alexey V., Aron, Allegra, Dorrestein, Pieter C., Atkinson, Paul H., Keyzers, Robert A., Munkacsi, Andrew B.

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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk von Dunlop, Malcolm G, Dobbins, Sara E, Farrington, Susan Mary, Jones, Angela M, Palles, Claire, Whiffin, Nicola, Tenesa, Albert, Spain, Sarah, Broderick, Peter, Ooi, Li-Yin, Domingo, Enric, Smillie, Claire, Henrion, Marc, Frampton, Matthew, Martin, Lynn, Grimes, Graeme, Gorman, Maggie, Semple, Colin, Ma, Yusanne P, Barclay, Ella, Prendergast, James, Cazier, Jean-Baptiste, Olver, Bianca, Penegar, Steven, Lubbe, Steven, Chander, Ian, Carvajal-Carmona, Luis G, Ballereau, Stephane, Lloyd, Amy, Vijayakrishnan, Jayaram, Zgaga, Lina, Rudan, Igor, Theodoratou, Evropi, Starr, John M, Deary, Ian, Kirac, Iva, Kovacević, Dujo, Aaltonen, Lauri A, Renkonen-Sinisalo, Laura, Mecklin, Jukka-Pekka, Matsuda, Koichi, Nakamura, Yusuke, Okada, Yukinori, Gallinger, Steven, Duggan, David J, Conti, David, Newcomb, Polly, Hopper, John, Jenkins, Mark A, Schumacher, Fredrick, Casey, Graham, Easton, Douglas, Shah, Mitul, Pharoah, Paul, Lindblom, Annika, Liu, Tao, Smith, Christopher G, West, Hannah, Cheadle, Jeremy P, Midgley, Rachel, Kerr, David J, Campbell, Harry, Tomlinson, Ian P, Houlston, Richard S

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Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition von Feeney, Mary, MSc, RD, Du Toit, George, MBBCh, FRCPCH, Roberts, Graham, DM, Sayre, Peter H., MD, PhD, Lawson, Kaitie, MS, Bahnson, Henry T., MPH, Sever, Michelle L., MSPH, PhD, Radulovic, Suzana, MD, Plaut, Marshall, MD, Lack, Gideon, MBBCh, FRCPCH

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Diagnostic uncertainty presented barriers to the timely management of acute thrombotic thrombocytopenic purpura in the United Kingdom between 2014 and 2019 von Bull, Tom P., Nicolson, Phillip L. R., Doyle, Andrew J., Langridge, Alexander, Pettit, Michala, Perry, Rita, Thomas, William, Page, Catherine, Whalley, Ioana, Dutt, Tina, Garth, Louise, Lester, Will, Buka, Richard J., Subhan, Mary, Ware, Victoria, Etherington, Astrid, Carter‐Brzezinski, Luke, Corrigan, Claire, Benson, Gary, Zhao, Rui, Douglas, Kenneth, Smith, Sophie, Wolf, Julia, Todd, Sophie A., McDonald, Vickie, Rampotas, Alexandros, Dean, Christopher, Sangha, Gavinda, Pavord, Sue, Denny, Nicholas, Jaafar, Sarah, McLaughlin, David P. T., Ross, Jennifer E., Karanth, Mamatha, Beverstock, Sarah L., Mansonso, Lynn, McLaughlin, David P. T., Tauro, Sudhir, Shenouda, Amir, Bailiff, Benjamin M., Kajita, Daniel, Alford, Sarah, Pickard, Keir, Greystoke, Brigit, Abdussalam, Asmaa, Roberts, Lara N, Young, Jennifer, Maddox, Jamie, Wheeldon, Sarah L., Tahhan, Molham, Vickers, Mark, Hill, Quentin, Mustafa, Nadreen, Almaremi, Azza, Hughes, Emily, Loizou, Eleana, James, Izabela, Farmer, Isabel, Thanigaikumar, Murugaiyan, Kerr, Paul, Gooding, Richard, Thornton, Kathryn, Dixon, Kiri I., Crowe, Josephine, De Lord, Corinne, Sud, Amit, Bailey, Chris, Hall, Rachel, Gray, Benjamin, Chauhan, Salena R., Gudger, Amy, Horgan, Claire, Venkatadasari, Indrani, Kaddam, Israa, Mapplebeck, Claire L., Van Veen, Joost, Raj, Maya, De Abrew, Kanchana, Belsham, Edward, Gyansah, Cecilia, Sadullah, Shalal, Salhan, Beena, Murrin, Richard, Williams, Rhys L., Stewart, Andrew, Cornish, Naomi, Ackroyd, Sam, Chen, Lucia Y., Pemberton, Nicholas, Rawi, Emanal, Yong, Jun, Davies, David, Peck, Rachel C., Cahalin, Paul, Prodger, Catherine, Dutton, David A., Sternberg, Alexander J., Chengal, Rajani, Polzella, Paolo, Scully, Marie

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SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2 von Eales, Oliver, Page, Andrew J, de Oliveira Martins, Leonardo, Wang, Haowei, Bodinier, Barbara, Haw, David, Jonnerby, Jakob, Atchison, Christina, Ashby, Deborah, Barclay, Wendy, Taylor, Graham, Cooke, Graham, Ward, Helen, Darzi, Ara, Riley, Steven, Chadeau-Hyam, Marc, Donnelly, Christl A, Elliott, Paul

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Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes von McHugh, M.P., Rambaut, Andrew, Snell, Luke B., Jackson, David K., Moore, Catherine, Jackson, Leigh M., Aanensen, David M., Barrett, Jeffrey C., Bashton, Matthew, Wang, Dennis, Thomas, Claire, Simpson, David A., Paterson, Steve, Pybus, Oliver G., Taylor, Joshua F., Crown, Matthew R., Monahan, Irene M., Silviera, Siona, Harvey, William T., O'Toole, Áine, Kitchman, Katie, Dervisevic, Samir, Barrow, Magdalena, Xu-McCrae, Li, Cox, Alison, Withell, Karen T., Denton-Smith, Rebecca, Sloan, Tim J., Pymont, Hannah M., Crudgington, Dorian, Iturriza-Gomara, Miren, Rooke, Stefan, Yebra, Gonzalo, Blane, Beth, Green, Angie, Kay, Sally, Reynolds, Nicola, Hollis, Amy, Yew, Wen C., Hey, Jessica, Jones, Hannah, Hornsby, Hailey R., Pohare, Manoj, Boyd, Olivia, Jackson, Chris, Vattipally, Sreenu, de Oliveira Martins, Leonardo, Jackson, Ben, Medd, Nathan, Smith, Ken, Guest, Martyn, Kitchen, Christine, Churcher, Carol M., Delgado Callico, Laia, Judges, Sarah, Bolt, Frances, De Lacy, Elen, Foulser, Luke, Boswell, Tim, Howson-Wells, Hannah C., Khakh, Manjinder, Lister, Michelle M., Helmer, Thomas, Hughes, Warwick, Lee, Jack CD, Shah, Divya, Ohemeng-Kumi, Natasha, Sluga, Graciela, Ahmad, Shazaad SY, Barton, Edward, Scott, Garren, Johnson, Kate, Lawton, Andrew I., Ashfield, Paula, Best, Angus, Crawford, Liam, Ensell, Leah, Easton, Lisa J., Nicodemi, Roberto, Beggs, Andrew, Dias, Joana, Park, Emily J., Francois, Sarah, Ragonnet-Cronin, Manon, Nichols, Jenna, Nomikou, Kyriaki, Tsatsani, Ioulia, Hubb, Jonathan, Manesis, Nikos, Aydin, Alp, Foster-Nyarko, Ebenezer, Prosolek, Sophie J., Mariappan, Arun, Bayzid, Nadua, Cotic, Marius, Michelsen, Michelle L., Eccles, Richard, Gemmell, Matthew, Gregory, Richard, Bronner, Iraad F.

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