Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer von Chubb, Daniel, Broderick, Peter, Dobbins, Sara E., Frampton, Matthew, Kinnersley, Ben, Penegar, Steven, Price, Amy, Ma, Yussanne P., Sherborne, Amy L., Palles, Claire, Timofeeva, Maria N., Bishop, D. Timothy, Dunlop, Malcolm G., Tomlinson, Ian, Houlston, Richard S.

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Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly di... von Jones, John R, Weinhold, Niels, Ashby, Cody, Walker, Brian A, Wardell, Chris, Pawlyn, Charlotte, Rasche, Leo, Melchor, Lorenzo, Cairns, David A, Gregory, Walter M, Johnson, David, Begum, Dil B, Ellis, Sidra, Sherborne, Amy L, Cook, Gordon, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Jackson, Graham H, Davies, Faith E, Greaves, Mel, Morgan, Gareth J

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Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype von Migliorini, Gabriele, Fiege, Bettina, Hosking, Fay J., Ma, Yussanne, Kumar, Rajiv, Sherborne, Amy L., da Silva Filho, Miguel Inacio, Vijayakrishnan, Jayaram, Koehler, Rolf, Thomsen, Hauke, Irving, Julie A., Allan, James M., Lightfoot, Tracy, Roman, Eve, Kinsey, Sally E., Sheridan, Eamonn, Thompson, Pamela, Hoffmann, Per, Nöthen, Markus M., Mühleisen, Thomas W., Eisele, Lewin, Zimmermann, Martin, Bartram, Claus R., Schrappe, Martin, Greaves, Mel, Stanulla, Martin, Hemminki, Kari, Houlston, Richard S.

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Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk von Gast, Andreas, Kinsey, Sally E, Roman, Eve, Schrappe, Martin, Koeffler, H Phillip, Hosking, Fay J, Stanulla, Martin, Sinnett, Daniel, Harrison, Christine J, Vijayakrishnan, Jayaram, Dobbins, Sara E, Houlston, Richard S, Zimmermann, Martin, Erdelyi, Daniel J, Bartram, Claus R, Richards, Sue, Neira, Anna Gonzalez, Ogawa, Seishi, Healy, Jasmine, Hemminki, Kari, Papaemmanuil, Elli, Kawamata, Norihiko, Semsei, Ágnes F, Irving, Julie A E, Sherborne, Amy L, Kumar, Rajiv, Ma, Yussanne, Moorman, Anthony V, Greaves, Mel, Lightfoot, Tracey, Koehler, Rolf, Prasad, Rashmi B, Taylor, Malcolm, Szalai, Csaba, Sheridan, Eamonn, Allan, James M, Tomlinson, Ian P, Krajinovic, Maja

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A pooled mutational analysis identifies ionizing radiation-associated mutational signatures conserved between mouse and human malignancies von Davidson, Philip R., Sherborne, Amy L., Taylor, Barry, Nakamura, Alice O., Nakamura, Jean L.

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Mutational Analysis of Ionizing Radiation Induced Neoplasms von Sherborne, Amy L., Davidson, Philip R., Yu, Katharine, Nakamura, Alice O., Rashid, Mamunur, Nakamura, Jean L.

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The Genetic Basis of Inbreeding Avoidance in House Mice von Sherborne, Amy L., Thom, Michael D., Paterson, Steve, Jury, Francine, Ollier, William E.R., Stockley, Paula, Beynon, Robert J., Hurst, Jane L.

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Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors von Sherborne, Amy L, Lavergne, Vincent, Yu, Katharine, Lee, Leah, Davidson, Philip R, Mazor, Tali, Smirnoff, Ivan V, Horvai, Andrew E, Loh, Mignon, DuBois, Steven G, Goldsby, Robert E, Neglia, Joseph P, Hammond, Sue, Robison, Leslie L, Wustrack, Rosanna, Costello, Joseph F, Nakamura, Alice O, Shannon, Kevin M, Bhatia, Smita, Nakamura, Jean L

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Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia von Ma, Yussanne, Dobbins, Sara E., Sherborne, Amy L., Chubb, Daniel, Galbiati, Marta, Cazzaniga, Giovanni, Micalizzi, Concetta, Tearle, Rick, Lloyd, Amy L., Hain, Richard, Greaves, Mel, Houlston, Richard S.

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An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics von Hoang, Phuc H., Cornish, Alex J., Sherborne, Amy L., Chubb, Daniel, Kimber, Scott, Jackson, Graham, Morgan, Gareth J., Cook, Gordon, Kinnersley, Ben, Kaiser, Martin, Houlston, Richard S.

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Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers von Ojha, Juhi, Dyagil, Iryna, Finch, Stuart C, Reiss, Robert F, de Smith, Adam J, Gonseth, Semira, Zhou, Mi, Hansen, Helen M, Sherborne, Amy L, Nakamura, Jean, Bracci, Paige M, Gudzenko, Nataliya, Hatch, Maureen, Babkina, Nataliya, Little, Mark P, Chumak, Vadim V, Walsh, Kyle M, Bazyka, Dimitry, Wiemels, Joseph L, Zablotska, Lydia B

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Copy number evolution and its relationship with patient outcome—an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial von Croft, James, Ellis, Sidra, Sherborne, Amy L., Sharp, Kim, Price, Amy, Jenner, Matthew W., Drayson, Mark T., Owen, Roger G., Chown, Sally, Lindsay, Jindriska, Karunanithi, Kamaraj, Hunter, Hannah, Gregory, Walter M., Davies, Faith E., Morgan, Gareth J., Cook, Gordon, Atanesyan, Lilit, Savola, Suvi, Cairns, David A., Jackson, Graham, Houlston, Richard S., Kaiser, Martin F.

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Predicting ultrahigh risk multiple myeloma by molecular profiling: an analysis of newly diagnosed transplant eligible myeloma XI trial patients von Shah, Vallari, Sherborne, Amy L., Johnson, David C., Ellis, Sidra, Price, Amy, Chowdhury, Farzana, Kendall, Jack, Jenner, Matthew W., Drayson, Mark T., Owen, Roger G., Gregory, Walter M., Morgan, Gareth J., Davies, Faith E., Cook, Gordon, Cairns, David A., Houlston, Richard S., Jackson, Graham, Kaiser, Martin F.

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Subclonal TP53 copy number is associated with prognosis in multiple myeloma von Shah, Vallari, Johnson, David C., Sherborne, Amy L., Ellis, Sidra, Aldridge, Frances M., Howard-Reeves, Julie, Begum, Farzana, Price, Amy, Kendall, Jack, Chiecchio, Laura, Savola, Suvi, Jenner, Matthew W., Drayson, Mark T., Owen, Roger G., Gregory, Walter M., Morgan, Gareth J., Davies, Faith E., Houlston, Richard S., Cook, Gordon, Cairns, David A., Jackson, Graham, Kaiser, Martin F.

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High-Throughput Molecular Cancer Cell Line Characterization Using Digital Multiplex Ligation-Dependent Probe Amplification for Improved Standardization of in Vitro Research von Menezes, Karen, Atanesyan, Lilit, Sherborne, Amy L., Steenkamer, Maryvonne, Clemens, Ivo, Savola, Suvi, Kaiser, Martin F.

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Baculum morphology predicts reproductive success of male house mice under sexual selection von Stockley, Paula, Ramm, Steven A, Sherborne, Amy L, Thom, Michael D F, Paterson, Steve, Hurst, Jane L

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The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia von Dobbins, Sara E., Sherborne, Amy L., Ma, Yussanne P., Bardini, Michela, Biondi, Andrea, Cazzaniga, Giovanni, Lloyd, Amy, Chubb, Daniel, Greaves, Mel F., Houlston, Richard S.

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Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes von Dobbins, Sara E., Broderick, Peter, Chubb, Daniel, Kinnersley, Ben, Sherborne, Amy L., Houlston, Richard S.

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What are genome-wide association studies telling us about B-cell tumor development? von Sherborne, Amy L, Houlston, Richard S

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Prognostic Molecular Stratification in Relapsed/Refractory Multiple Myeloma - Results of the Pomalidomide Mukseven (NCT02406222) Biomarker Trial von Croft, James, Hall, Andrew, Sherborne, Amy L, Walker, Katrina, Ellis, Sidra, Sharp, Kim, Price, Amy, Pawlyn, Charlotte, Flanagan, Louise, Garg, Mamta, Couto, Suzana, Wang, Maria, Boyd, Kevin, Pierceall, William E, Thakurta, Anjan, Cook, Gordon, Brown, Sarah R, Kaiser, Martin F.

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