Constraining Cyclic Peptides To Mimic Protein Structure Motifs von Hill, Timothy A., Shepherd, Nicholas E., Diness, Frederik, Fairlie, David P.

Volltext

CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex von Low, Jason K.K., Webb, Sarah R., Silva, Ana P.G., Saathoff, Hinnerk, Ryan, Daniel P., Torrado, Mario, Brofelth, Mattias, Parker, Benjamin L., Shepherd, Nicholas E., Mackay, Joel P.

Volltext

The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture von Low, Jason K.K., Silva, Ana P.G., Sharifi Tabar, Mehdi, Torrado, Mario, Webb, Sarah R., Parker, Benjamin L., Sana, Maryam, Smits, Callum, Schmidberger, Jason W., Brillault, Lou, Jackman, Matthew J., Williams, David C., Blobel, Gerd A., Hake, Sandra B., Shepherd, Nicholas E., Landsberg, Michael J., Mackay, Joel P.

Volltext

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency von Harrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Ruiz-Gómez, Gloria, Hill, Timothy A., Driver, Russell W., Desai, Vishal S., Young, Paul R., Abbenante, Giovanni, Fairlie, David P., Klibanov, Alexander M.

Volltext

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus von Gamsjaeger, Roland, Kariawasam, Ruvini, Gimenez, Adrian X, Touma, Christine, McIlwain, Elysse, Bernardo, Ray E, Shepherd, Nicholas E, Ataide, Sandro F, Dong, Qihan, Richard, Derek J, White, Malcolm F, Cubeddu, Liza

Volltext

Orally Absorbed Cyclic Peptides von Nielsen, Daniel S, Shepherd, Nicholas E, Xu, Weijun, Lucke, Andrew J, Stoermer, Martin J, Fairlie, David P

Volltext

Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies von Shepherd, Nicholas E., Gamsjaeger, Roland, Vandevenne, Marylène, Cubeddu, Liza, Mackay, Joel P.

Volltext

A Heterobimetallic Ga/Yb-Schiff Base Complex for Catalytic Asymmetric α-Addition of Isocyanides to Aldehydes von Mihara, Hisashi, Xu, Yingjie, Shepherd, Nicholas E, Matsunaga, Shigeki, Shibasaki, Masakatsu

Volltext

Direct Catalytic Asymmetric Vinylogous Mannich-Type and Michael Reactions of an α,β-Unsaturated γ-Butyrolactam under Dinuclear Nickel Catalysis von Shepherd, Nicholas E, Tanabe, Hirooki, Xu, Yingjie, Matsunaga, Shigeki, Shibasaki, Masakatsu

Volltext

The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins von Clifton, Molly K, Westman, Belinda J, Thong, Sock Yue, O'Connell, Mitchell R, Webster, Michael W, Shepherd, Nicholas E, Quinlan, Kate G, Crossley, Merlin, Blobel, Gerd A, Mackay, Joel P

Volltext

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice von Harrison, Rosemary S, Ruiz-Gómez, Gloria, Hill, Timothy A, Chow, Shiao Y, Shepherd, Nicholas E, Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N, Fairlie, David P

Volltext

Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex von Torrado, Mario, Low, Jason K. K., Silva, Ana P. G., Schmidberger, Jason W., Sana, Maryam, Sharifi Tabar, Mehdi, Isilak, Musa E., Winning, Courtney S., Kwong, Cherry, Bedward, Max J., Sperlazza, Mary J., Williams, David C., Shepherd, Nicholas E., Mackay, Joel P.

Volltext

Helix Nucleation by the Smallest Known α-Helix in Water von Hoang, Huy N., Driver, Russell W., Beyer, Renée L., Hill, Timothy A., D. de Araujo, Aline, Plisson, Fabien, Harrison, Rosemary S., Goedecke, Lena, Shepherd, Nicholas E., Fairlie, David P.

Volltext

Single Turn Peptide Alpha Helices with Exceptional Stability in Water von Shepherd, Nicholas E, Hoang, Huy N, Abbenante, Giovanni, Fairlie, David P

Volltext

Structural Basis for Phosphorylation and Lysine Acetylation Cross-talk in a Kinase Motif Associated with Myocardial Ischemia and Cardioprotection von Parker, Benjamin L., Shepherd, Nicholas E., Trefely, Sophie, Hoffman, Nolan J., White, Melanie Y., Engholm-Keller, Kasper, Hambly, Brett D., Larsen, Martin R., James, David E., Cordwell, Stuart J.

Volltext

Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex von Alqarni, Saad S M, Murthy, Andal, Zhang, Wei, Przewloka, Marcin R, Silva, Ana P G, Watson, Aleksandra A, Lejon, Sara, Pei, Xue Y, Smits, Arne H, Kloet, Susan L, Wang, Hongxin, Shepherd, Nicholas E, Stokes, Philippa H, Blobel, Gerd A, Vermeulen, Michiel, Glover, David M, Mackay, Joel P, Laue, Ernest D

Volltext

Correction: Twists or turns: stabilising alpha vs. beta turns in tetrapeptides von Hoang, Huy N., Hill, Timothy A., Ruiz-Gómez, Gloria, Diness, Frederik, Mason, Jody M., Wu, Chongyang, Abbenante, Giovanni, Shepherd, Nicholas E., Fairlie, David P.

Volltext

Twists or turns: stabilising alpha vs. beta turns in tetrapeptides von Hoang, Huy N, Hill, Timothy A, Ruiz-Gómez, Gloria, Diness, Frederik, Mason, Jody M, Wu, Chongyang, Abbenante, Giovanni, Shepherd, Nicholas E, Fairlie, David P

Volltext

Downsizing the BAD BH3 peptide to small constrained α-helices with improved ligand efficiency von Shepherd, Nicholas E, Harrison, Rosemary S, Ruiz-Gomez, Gloria, Abbenante, Giovanni, Mason, Jody M, Fairlie, David P

Volltext

Left- and Right-Handed Alpha-Helical Turns in Homo- and Hetero-Chiral Helical Scaffolds von Shepherd, Nicholas E, Hoang, Huy N, Abbenante, Giovanni, Fairlie, David P

Volltext