Abstract 1244 Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13 von Liu, Shenping

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Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13 von Liu, Shenping, Sommese, Ruth F., Nedoma, Nicole L., Stevens, Lucy Mae, Dutra, Jason K., Zhang, Liying, Edmonds, David J., Wang, Yang, Garnsey, Michelle, Clasquin, Michelle F.

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A covalent BTK ternary complex compatible with targeted protein degradation von Schiemer, James, Maxwell, Andrew, Horst, Reto, Liu, Shenping, Uccello, Daniel P., Borzilleri, Kris, Rajamohan, Nisha, Brown, Matthew F., Calabrese, Matthew F.

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Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes von Hett, Erik C, Xu, Hua, Geoghegan, Kieran F, Gopalsamy, Ariamala, Kyne, Robert E, Menard, Carol A, Narayanan, Arjun, Parikh, Mihir D, Liu, Shenping, Roberts, Lee, Robinson, Ralph P, Tones, Michael A, Jones, Lyn H

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Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study von Du, Yongming, Hu, Yichao, Sheng, Yuehua, Zhu, Tianhong, Liu, Shenping, Ding, Huiqing, Guan, Yutao

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Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy von Verhoest, Patrick R, Proulx-Lafrance, Caroline, Corman, Michael, Chenard, Lois, Helal, Christopher J, Hou, Xinjun, Kleiman, Robin, Liu, Shenping, Marr, Eric, Menniti, Frank S, Schmidt, Christopher J, Vanase-Frawley, Michelle, Schmidt, Anne W, Williams, Robert D, Nelson, Frederick R, Fonseca, Kari R, Liras, Spiros

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Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies von Conrad, Karen S., Cheng, Ting-Wen, Ysselstein, Daniel, Heybrock, Saskia, Hoth, Lise R., Chrunyk, Boris A., am Ende, Christopher W., Krainc, Dimitri, Schwake, Michael, Saftig, Paul, Liu, Shenping, Qiu, Xiayang, Ehlers, Michael D.

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Use of complementary biophysical methods to characterize ligand binding to IL-17A von Sahasrabudhe, Parag, Liu, Shenping

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Structural Basis for the Guanine Nucleotide-Binding Activity of Tissue Transglutaminase and Its Regulation of Transamidation Activity von Liu, Shenping, Cerione, Richard A., Clardy, Jon

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Understanding the Impact of the P-loop Conformation on Kinase Selectivity von Guimarães, Cristiano R. W, Rai, Brajesh K, Munchhof, Michael J, Liu, Shenping, Wang, Jian, Bhattacharya, Samit K, Buckbinder, Leonard

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Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin von Liu, Shenping, Widom, Joanne, Kemp, Christopher W., Crews, Craig M., Clardy, Jon

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Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potent d-Amino Acid Oxidase (DAAO) Inhibitors von Duplantier, Allen J, Becker, Stacey L, Bohanon, Michael J, Borzilleri, Kris A, Chrunyk, Boris A, Downs, James T, Hu, Lain-Yen, El-Kattan, Ayman, James, Larry C, Liu, Shenping, Lu, Jiemin, Maklad, Noha, Mansour, Mahmoud N, Mente, Scot, Piotrowski, Mary A, Sakya, Subas M, Sheehan, Susan, Steyn, Stefanus J, Strick, Christine A, Williams, Victoria A, Zhang, Lei

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Discovery and structural characterization of an allosteric inhibitor of bacterial cis‐prenyltransferase von Danley, Dennis E., Baima, Eric T., Mansour, Mahmoud, Fennell, Kimberly F., Chrunyk, Boris A., Mueller, John P., Liu, Shenping, Qiu, Xiayang

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Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase von Liu, Shenping, Knafels, John D., Chang, Jeanne S., Waszak, Gregory A., Baldwin, Eric T., Deibel, Martin R., Thomsen, Darrell R., Homa, Fred L., Wells, Peter A., Tory, Monica C., Poorman, Roger A., Gao, Hua, Qiu, Xiayang, Seddon, Andrew P.

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The role of the SOX2 gene in cervical cancer: focus on ferroptosis and construction of a predictive model von Liu, Shenping, Wei, Zhi, Ding, Huiqing

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Structural basis for the catalytic mechanism of human phosphodiesterase 9 von Liu, Shenping, Mansour, Mahmoud N, Dillman, Keith S, Perez, Jose R, Danley, Dennis E, Aeed, Paul A, Simons, Samuel P, LeMotte, Peter K, Menniti, Frank S

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1-((3 S,4 S)-4-Amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes von Andrews, Kim M., Beebe, David A., Benbow, John W., Boyer, David A., Doran, Shawn D., Hui, Yu, Liu, Shenping, McPherson, R. Kirk, Neagu, Constantin, Parker, Janice C., Piotrowski, David W., Schneider, Steven R., Treadway, Judith L., VanVolkenberg, Maria A., Zembrowski, William J.

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The RESOLUTE consortium: unlocking SLC transporters for drug discovery von Superti-Furga, Giulio, Lackner, Daniel, Wiedmer, Tabea, Ingles-Prieto, Alvaro, Barbosa, Barbara, Girardi, Enrico, Goldmann, Ulrich, Gürtl, Bettina, Klavins, Kristaps, Klimek, Christoph, Lindinger, Sabrina, Liñeiro-Retes, Eva, Müller, André C., Onstein, Svenja, Redinger, Gregor, Reil, Daniela, Sedlyarov, Vitaly, Wolf, Gernot, Crawford, Matthew, Everley, Robert, Hepworth, David, Noell, Stephen, Piotrowski, Mary, Stanton, Robert, Zhang, Hui, Corallino, Salvatore, Faedo, Andrea, Insidioso, Maria, Maresca, Giovanna, Redaelli, Loredana, Sassone, Francesca, Scarabottolo, Lia, Stucchi, Michela, Tarroni, Paola, Tremolada, Sara, Batoulis, Helena, Becker, Andreas, Bender, Eckhard, Chang, Yung-Ning, Ehrmann, Alexander, Müller-Fahrnow, Anke, Pütter, Vera, Zindel, Diana, Hamilton, Bradford, Lenter, Martin, Santacruz, Diana, Viollet, Coralie, Whitehurst, Charles, Johnsson, Kai, Leippe, Philipp, Baumgarten, Birgit, Chang, Lena, Ibig, Yvonne, Pfeifer, Martin, Reinhardt, Jürgen, Schönbett, Julian, Selzer, Paul, Seuwen, Klaus, Bettembourg, Charles, Biton, Bruno, Czech, Jörg, de Foucauld, Hélène, Didier, Michel, Licher, Thomas, Mikol, Vincent, Pommereau, Antje, Puech, Frédéric, Yaligara, Veeranagouda, Edwards, Aled, Bongers, Brandon J., Heitman, Laura H., IJzerman, Ad P., Sijben, Huub J., van Westen, Gerard J.P., Grixti, Justine, Kell, Douglas B., Mughal, Farah, Swainston, Neil, Wright-Muelas, Marina, Burgess-Brown, Nicola, Carpenter, Liz, Dürr, Katharina, Hansen, Jesper, Scacioc, Andreea, Colas, Claire, Digles, Daniela, Ecker, Gerhard, Füzi, Barbara, Gamsjäger, Viktoria, Grandits, Melanie, Martini, Riccardo, Troger, Florentina, Altermatt, Patrick, Doucerain, Cédric, Dürrenberger, Franz, Manolova, Vania, Steck, Anna-Lena, Sundström, Hanna, Wilhelm, Maria, Steppan, Claire M.

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Crystal Structure of a Human IκB Kinase β Asymmetric Dimer von Liu, Shenping, Misquitta, Yohann R., Olland, Andrea, Johnson, Mark A., Kelleher, Kerry S., Kriz, Ron, Lin, Laura L., Stahl, Mark, Mosyak, Lidia

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Seq2Set2Seq: A Two-stage Disentangled Method for Reply Keyword Generation in Social Media von Liu, Jie, Li, Yaguang, He, Shizhu, Wu, Shun, Liu, Kang, Liu, Shenping, Wang, Jiong, Zhang, Qing

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