Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8 von Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng-Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.

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A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors von Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark

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Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti–programmed cell death protein-1 (PD-1) antibody, in human cancer models von DeAngelis, Nikki, Ferrante, Catherine, Powers, Gordon, Sendecki, Jocelyn, Mattson, Bethany, Pizutti, Darlene, Packman, Kathryn, Wang, Weirong, Trouba, Kevin, Nanjunda, Rupesh, Wheeler, John, Brittingham, Ray, Wu, Sheng-Jiun, Luo, Jinquan, Lorenzi, Matthew V., Verona, Raluca I.

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"Stapling" scFv for multispecific biotherapeutics of superior properties von Boucher, Lauren E, Prinslow, Elisabeth Geyer, Feldkamp, Michael, Yi, Fang, Nanjunda, Rupesh, Wu, Sheng-Jiun, Liu, Tun, Lacy, Eilyn R, Jacobs, Steven, Kozlyuk, Natalia, Del Rosario, Brian, Wu, Bingyuan, Aquino, Patricia, Davidson, Robert C, Heyne, Samantha, Mazzanti, Nicholas, Testa, James, Diem, Michael D, Gorre, Elsa, Mahan, Andrew, Nanda, Hirsh, Gunawardena, Harsha P, Gervais, Alexis, Armstrong, Anthony A, Teplyakov, Alexey, Huang, Chichi, Zwolak, Adam, Chowdhury, Partha, Cheung, Wan Cheung, Luo, Jinquan

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Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab von Luo, Jinquan, Wu, Sheng-Jiun, Lacy, Eilyn R., Orlovsky, Yevgeniya, Baker, Audrey, Teplyakov, Alexey, Obmolova, Galina, Heavner, George A., Richter, Hans-Thomas, Benson, Jacqueline

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Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure von Luo, Jinquan, Obmolova, Galina, Malia, Thomas J., Wu, Sheng-Jiun, Duffy, Karen E., Marion, James D., Bell, Jessica K., Ge, Peng, Zhou, Z. Hong, Teplyakov, Alexey, Zhao, Yonghong, Lamb, Roberta J., Jordan, Jarrat L., San Mateo, Lani R., Sweet, Raymond W., Gilliland, Gary L.

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Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung von Santulli-Marotto, Sandra, Boakye, Ken, Lacy, Eilyn, Wu, Sheng-Jiun, Luongo, Jennifer, Kavalkovich, Karl, Coelho, Ana, Hogaboam, Cory M, Ryan, Mary

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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality von Tam, Susan, McCarthy, Stephen, Armstrong, Anthony, Somani, Sandeep, Wu, Sheng-Jiun, Liu, Xuesong, Gervais, Alexis, Ernst, Robin, Saro, Dorina, Decker, Rose, Luo, Jinquan, Gilliland, Gary, Chiu, Mark, Scallon, Bernard

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Structure of the EMMPRIN N-terminal domain 1: Dimerization via β-strand swapping von Luo, Jinquan, Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas, Wu, Sheng-Jiun, Beil, Eric, Baker, Audrey, Swencki-Underwood, Bethany, Zhao, Yonghong, Sprenkle, Justin, Dixon, Ken, Sweet, Raymond, Gilliland, Gary L.

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Cross-Interaction Chromatography: A Rapid Method to Identify Highly Soluble Monoclonal Antibody Candidates von Jacobs, Steven A., Wu, Sheng-Jiun, Feng, Yiqing, Bethea, Deidra, O’Neil, Karyn T.

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Probing the solution structure of tumor necrosis factor-α homotrimer and heterotrimer after complex perturbation using electrospray ionization mass spectrometry von Beil, Eric J., Heavner, George A., Wu, Sheng-Jiun, Nemeth, Jennifer F.

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Mechanisms of self-association of a human monoclonal antibody CNTO607 von Bethea, Deidra, Wu, Sheng-Jiun, Luo, Jinquan, Hyun, Linus, Lacy, Eilyn R., Teplyakov, Alexey, Jacobs, Steven A., O'Neil, Karyn T., Gilliland, Gary L., Feng, Yiqing

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Use of biased-relay feedback for system identification von Shen, Shih-Haur, Wu, Jiun-Sheng, Yu, Cheng-Ching

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Structure-based engineering of a monoclonal antibody for improved solubility von Wu, Sheng-Jiun, Luo, Jinquan, O'Neil, Karyn T., Kang, James, Lacy, Eilyn R., Canziani, Gabriela, Baker, Audrey, Huang, Maggie, Tang, Qing Mike, Raju, T.Shantha, Jacobs, Steven A., Teplyakov, Alexey, Gilliland, Gary L., Feng, Yiqing

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A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia von Nair-Gupta, Priyanka, Diem, Michael, Reeves, Dara, Wang, Weirong, Schulingkamp, Robert, Sproesser, Katrin, Mattson, Bethany, Heidrich, Bradley, Mendonça, Mark, Joseph, Jocelin, Sendecki, Jocelyn, Foulk, Brad, Chu, Gerald, Fink, Damien, Jiao, Qun, Wu, Sheng-Jiun, Packman, Kathryn, Elsayed, Yusri, Attar, Ricardo, Gaudet, François

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Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines von Fursov, Natalie, Lu, Jin, Healy, Catherine, Wu, Sheng-Jiun, Lacy, Eilyn, Filer, Angela, Li, Yawei, Liu, Changbao, Lamb, Roberta, Jones, Brian, Reddy, Ramachandra, Petley, Ted, Duffy, Karen

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A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody von Fisher, Paul W, Brigham-Burke, Michael, Wu, Sheng-Jiun, Luo, Jinquan, Carton, Jill, Staquet, Kim, Gao, Wei, Jackson, Sheila, Bethea, Deidra, Chen, Cailin, Hu, Bing, Giles-Komar, Jill, Yang, Jing

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Epitope Mapping of Anti-Interleukin-13 Neutralizing Antibody CNTO607 von Teplyakov, Alexey, Obmolova, Galina, Wu, Sheng-Jiun, Luo, Jinquan, Kang, James, O'Neil, Karyn, Gilliland, Gary L.

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CCL22-specific Antibodies Reveal That Engagement of Two Distinct Binding Domains on CCL22 Is Required for CCR4-mediated Function von Santulli-Marotto, Sandra, Wheeler, John, Lacy, Eilyn R., Boakye, Ken, Luongo, Jennifer, Wu, Sheng-Jiun, Ryan, Mary

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Characterization of the epitope for anti-human respiratory syncytial virus F protein monoclonal antibody 101F using synthetic peptides and genetic approaches von Wu, Sheng-Jiun, Schmidt, Albert, Beil, Eric J, Day, Nicole D, Branigan, Patrick J, Liu, Changbao, Gutshall, Lester L, Palomo, Concepcion, Furze, Julie, Taylor, Geraldine, Melero, Jose A, Tsui, Ping, Del Vecchio, Alfred M, Kruszynski, Marian

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