Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion von Voli, Florida, Valli, Emanuele, Lerra, Luigi, Kimpton, Kathleen, Saletta, Federica, Giorgi, Federico M, Mercatelli, Daniele, Rouaen, Jourdin R C, Shen, Sylvie, Murray, Jayne E, Ahmed-Cox, Aria, Cirillo, Giuseppe, Mayoh, Chelsea, Beavis, Paul A, Haber, Michelle, Trapani, Joseph A, Kavallaris, Maria, Vittorio, Orazio

Volltext

Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice von CHUNLING HUANG, SHEN, Sylvie, QING MA, CHEN, Jason, GILL, Anthony, POLLOCK, Carol A, CHEN, Xin-Ming

Volltext

MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells von Tang, Owen, Chen, Xin-Ming, Shen, Sylvie, Hahn, Michael, Pollock, Carol A

Volltext

Inhibition of kidney proximal tubular glucose reabsorption does not prevent against diabetic nephropathy in type 1 diabetic eNOS knockout mice von Gangadharan Komala, Muralikrishna, Gross, Simon, Mudaliar, Harshini, Huang, Chunling, Pegg, Katherine, Mather, Amanda, Shen, Sylvie, Pollock, Carol A, Panchapakesan, Usha

Volltext

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG von Ehteda, Anahid, Simon, Sandy, Franshaw, Laura, Giorgi, Federico M., Liu, Jie, Joshi, Swapna, Rouaen, Jourdin R.C., Pang, Chi Nam Ignatius, Pandher, Ruby, Mayoh, Chelsea, Tang, Yujie, Khan, Aaminah, Ung, Caitlin, Tolhurst, Ornella, Kankean, Anne, Hayden, Elisha, Lehmann, Rebecca, Shen, Sylvie, Gopalakrishnan, Anjana, Trebilcock, Peter, Gurova, Katerina, Gudkov, Andrei V., Norris, Murray D., Haber, Michelle, Vittorio, Orazio, Tsoli, Maria, Ziegler, David S.

Volltext

TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells von Truong, Peter, Shen, Sylvie, Joshi, Swapna, Islam, Md Imtiazul, Zhong, Ling, Raftery, Mark J., Afrasiabi, Ali, Alinejad-Rokny, Hamid, Nguyen, Mary, Zou, Xiaoheng, Bhuyan, Golam Sarower, Sarowar, Chowdhury H., Ghodousi, Elaheh S., Stonehouse, Olivia, Mohamed, Sara, Toscan, Cara E., Connerty, Patrick, Kakadia, Purvi M., Bohlander, Stefan K., Michie, Katharine A., Larsson, Jonas, Lock, Richard B., Walkley, Carl R., Thoms, Julie A. I., Jolly, Christopher J., Pimanda, John E.

Volltext

Towards a clinically relevant lentiviral transduction protocol for primary human CD34 hematopoietic stem/progenitor cells von Millington, Michelle, Arndt, Allison, Boyd, Maureen, Applegate, Tanya, Shen, Sylvie

Volltext

Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling von Yong, Rachel, Chen, Xin-Ming, Shen, Sylvie, Vijayaraj, Swarna, Ma, Qing, Pollock, Carol A, Saad, Sonia

Volltext

GSK3 inhibition prevents lethal GVHD in mice von Klamer, Guy, Shen, Sylvie, Song, Emma, Rice, Alison M, Knight, Robert, Lindeman, Robert, O’Brien, Tracey A, Dolnikov, Alla

Volltext

Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success von Mcintyre, Glen J, Yu, Yi-Hsin, Tran, Anna, Jaramillo, Angel B, Arndt, Allison J, Millington, Michelle L, Boyd, Maureen P, Elliott, Fiona A, Shen, Sylvie W, Murray, John M, Applegate, Tanya L

Volltext

96 shRNAs designed for maximal coverage of HIV-1 variants von McIntyre, Glen John, Groneman, Jennifer Lynne, Yu, Yi-Hsin, Jaramillo, Angel, Shen, Sylvie, Applegate, Tanya Lynn

Volltext

Increasing Stem Cell Dose Promotes Posttransplant Immune Reconstitution von Xu, Ning, Shen, Sylvie, Dolnikov, Alla

Volltext

Abstract 3224: Copper homeostasis: A new player in anti-tumor immune response von Voli, Florida, Lerra, Luigi, Kimpton, Kathleen, Saletta, Federica, Shen, Sylvie, Cirillo, Giuseppe, Kavallaris, Maria, Vittorio, Orazio

Volltext

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs von Subramanian, Shruthi, Thoms, Julie A. I., Huang, Yizhou, Cornejo-Páramo, Paola, Koch, Forrest C., Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D., Pitson, Stuart M., Gandhi, Maher K., Lane, Steven W., Vafaee, Fatemeh, Wong, Emily S., Göttgens, Berthold, Alinejad-Rokny, Hamid, Wong, Jason W. H., Pimanda, John E.

Volltext

Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and Sumoylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia von Truong, Peter, Shen, Sylvie, Joshi, Swapna, Afrasiabi, Ali, Zhong, Ling, Raftery, Mark J., Larsson, Jonas, Lock, Richard B., Walkley, Carl R., Rokny, Hamid Alinejad, Thoms, Julie A.I., Jolly, Christopher J., Pimanda, John E.

Volltext

Mutant N- ras preferentially drives human CD34 + hematopoietic progenitor cells into myeloid differentiation and proliferation both in vitro and in the NOD/SCID mouse von Shen, Sylvie W., Dolnikov, Alla, Passioura, Toby, Millington, Michelle, Wotherspoon, Simon, Rice, Alison, MacKenzie, Karen L., Symonds, Geoff

Volltext

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions von Subramanian, Shruthi, Thoms, Julie A.I., Huang, Yizhou, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S, Fajardo, Diego Chacon, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, Brien, Tracey O', Trickett, Annette, Powell, Jason, Pitson, Stuart M, Gandhi, Maher K., Cornejo, Paola, Wong, Emily, Lane, Steven W, Gottgens, Bertie, Rokny, Hamid Alinejad, Wong, Jason W.H, Pimanda, John E.

Volltext

Abstract 3760: Preclinical optimization of a low cost PiggyBac transposase (PB) generated CD19-specific chimeric antigen receptor T cell (CART19) product for a first in man trial u... von Bishop, David, Xu, Ning, Shen, Sylvie, O’Brien, Tracey, Gottlieb, David, Dolnikov, Alla, Micklethwaite, Kenneth

Volltext

KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis von Huang, Chunling, Shen, Sylvie, Ma, Qing, Gill, Anthony, Pollock, Carol A, Chen, Xin-Ming

Volltext

Stem Cell Approach to Generate Chimeric Antigen Receptor Modified Immune Effector Cells to Treat Cancer von Dolnikov, Alla, Sylvie, Shen, Xu, Ning, O’Brien, Tracey

Volltext