Synthetic Lethal Networks for Precision Oncology: Promises and Pitfalls von Shen, John Paul, Ideker, Trey

Volltext

Novel Third-Generation EGFR Tyrosine Kinase Inhibitors and Strategies to Overcome Therapeutic Resistance in Lung Cancer von Murtuza, Ayesha, Bulbul, Ajaz, Shen, John Paul, Keshavarzian, Parissa, Woodward, Brian D, Lopez-Diaz, Fernando J, Lippman, Scott M, Husain, Hatim

Volltext

TNNGen: Automated Design of Neuromorphic Sensory Processing Units for Time-Series Clustering von Vellaisamy, Prabhu, Nair, Harideep, Ratnakaram, Vamsikrishna, Gupta, Dhruv, Paul Shen, John

Volltext

Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions von Shen, John Paul, Zhao, Dongxin, Sasik, Roman, Luebeck, Jens, Birmingham, Amanda, Bojorquez-Gomez, Ana, Licon, Katherine, Klepper, Kristin, Pekin, Daniel, Beckett, Alex N, Sanchez, Kyle Salinas, Thomas, Alex, Kuo, Chih-Chung, Du, Dan, Roguev, Assen, Lewis, Nathan E, Chang, Aaron N, Kreisberg, Jason F, Krogan, Nevan, Qi, Lei, Ideker, Trey, Mali, Prashant

Volltext

A global transcriptional network connecting noncoding mutations to changes in tumor gene expression von Zhang, Wei, Bojorquez-Gomez, Ana, Velez, Daniel Ortiz, Xu, Guorong, Sanchez, Kyle S., Shen, John Paul, Chen, Kevin, Licon, Katherine, Melton, Collin, Olson, Katrina M., Yu, Michael Ku, Huang, Justin K., Carter, Hannah, Farley, Emma K., Snyder, Michael, Fraley, Stephanie I., Kreisberg, Jason F., Ideker, Trey

Volltext

Typing tumors using pathways selected by somatic evolution von Wang, Sheng, Ma, Jianzhu, Zhang, Wei, Shen, John Paul, Huang, Justin, Peng, Jian, Ideker, Trey

Volltext

Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion von Johnson, Trevor C, Chin, Matthew R, Han, Tianxu, Shen, John Paul, Rana, Tariq, Siegel, Dionicio

Volltext

ERCC1 and TS Expression as Prognostic and Predictive Biomarkers in Metastatic Colon Cancer von Choueiri, Michel B, Shen, John Paul, Gross, Andrew M, Huang, Justin K, Ideker, Trey, Fanta, Paul

Volltext

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease von Bradner, James E., Mak, Raymond, Tanguturi, Shyam K., Mazitschek, Ralph, Haggarty, Stephen J., Ross, Kenneth, Chang, Cindy Y., Bosco, Jocelyn, West, Nathan, Morse, Elizabeth, Lin, Katherine, Shen, John Paul, Kwiatkowski, Nicholas P., Gheldof, Nele, Dekker, Job, DeAngelo, Daniel J., Carr, Steven A., Schreiber, Stuart L., Golub, Todd R., Ebert, Benjamin L.

Volltext

Survival improvement for patients with metastatic colorectal cancer over twenty years von Zeineddine, Fadl A., Zeineddine, Mohammad A., Yousef, Abdelrahman, Gu, Yue, Chowdhury, Saikat, Dasari, Arvind, Huey, Ryan W., Johnson, Benny, Kee, Bryan, Lee, Michael S., Morelli, Maria Pia, Morris, Van K., Overman, Michael J., Parseghian, Christine, Raghav, Kanwal, Willis, Jason, Wolff, Robert A., Kawaguchi, Yoshikuni, Vauthey, Jean-Nicolas, Sun, Ryan, Kopetz, Scott, Shen, John Paul

Volltext

A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy von Srivas, Rohith, Shen, John Paul, Yang, Chih Cheng, Sun, Su Ming, Li, Jianfeng, Gross, Andrew M., Jensen, James, Licon, Katherine, Bojorquez-Gomez, Ana, Klepper, Kristin, Huang, Justin, Pekin, Daniel, Xu, Jia L., Yeerna, Huwate, Sivaganesh, Vignesh, Kollenstart, Leonie, van Attikum, Haico, Aza-Blanc, Pedro, Sobol, Robert W., Ideker, Trey

Volltext

Impact of COVID-19 on viral respiratory infection epidemiology in young children: A single-center analysis von Shen, David Paul, Vermeulen, François, Debeer, Anne, Lagrou, Katrien, Smits, Anne

Volltext

Lamotrigine-induced hemophagocytic lymphohistiocytosis with Takotsubo cardiomyopathy: a case report von Zhou, Jenny Y, Martinez, Jordan A, Shen, John Paul

Volltext

Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis von Wang, Lihua, Wang, Ergang, Prado Balcazar, Jorge, Wu, Zhenzhen, Xiang, Kun, Wang, Yi, Huang, Qiang, Negrete, Marcos, Chen, Kai‐Yuan, Li, Wei, Fu, Yujie, Dohlman, Anders, Mines, Robert, Zhang, Liwen, Kobayashi, Yoshihiko, Chen, Tianyi, Shi, Guizhi, Shen, John Paul, Kopetz, Scott, Tata, Purushothama Rao, Moreno, Victor, Gersbach, Charles, Crawford, Gregory, Hsu, David, Huang, Emina, Bu, Pengcheng, Shen, Xiling

Volltext

Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma von Yousef, Abdelrahman, Yousef, Mahmoud, Chowdhury, Saikat, Abdilleh, Kawther, Knafl, Mark, Edelkamp, Paul, Alfaro-Munoz, Kristin, Chacko, Ray, Peterson, Jennifer, Smaglo, Brandon G., Wolff, Robert A., Pant, Shubham, Lee, Michael S., Willis, Jason, Overman, Michael, Doss, Sudheer, Matrisian, Lynn, Hurd, Mark W., Snyder, Rebecca, Katz, Matthew H. G., Wang, Huamin, Maitra, Anirban, Shen, John Paul, Zhao, Dan

Volltext

The Provocative Roles of Platelets in Liver Disease and Cancer von Kanikarla Marie, Preeti, Fowlkes, Natalie W., Afshar-Kharghan, Vahid, Martch, Stephanie L., Sorokin, Alexey, Shen, John Paul, Morris, Van K., Dasari, Arvind, You, Nancy, Sood, Anil K., Overman, Michael J., Kopetz, Scott, Menter, David George

Volltext

Corrigendum: SemNet: Learning semantic attributes for human activity recognition with deep belief networks von Venkatachalam, Shanmuga, Nair, Harideep, Zeng, Ming, Tan, Cathy Shunwen, Mengshoel, Ole J, Shen, John Paul

Volltext

SemNet: Learning semantic attributes for human activity recognition with deep belief networks von Venkatachalam, Shanmuga, Nair, Harideep, Zeng, Ming, Tan, Cathy Shunwen, Mengshoel, Ole J, Shen, John Paul

Volltext

Ultrahigh-Density Screens for Genome-Wide Yeast EMAPs in a Single Plate von Licon, Katherine, Shen, John Paul, Munson, Brenton P., Michaca, Manuel, Fassino, Cole, Fassino, Luke, Kreisberg, Jason F., Ideker, Trey

Volltext

Regarding Blood‐Based Next‐Generation Sequencing Analysis of Appendiceal Cancers von Shen, John Paul

Volltext