Modulation of γ-secretase specificity using small molecule allosteric inhibitors von Shelton, Christopher C, Zhu, Lei, Chau, Deming, Yang, Li, Wang, Rong, Djaballah, Hakim, Zheng, Hui, Li, Yue-Ming

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Hydrogen Peroxide Generated Extracellularly by Receptor-Ligand Interaction Facilitates Cell Signaling von DeYulia, Garrett J., Cárcamo, Juan M., Bórquez-Ojeda, Oriana, Shelton, Christopher C., Golde, David W., Maniatis, Thomas

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γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity von MENG, Raymond D, SHELTON, Christopher C, LI, Yue-Ming, QIN, Li-Xuan, NOTTERMAN, Daniel, PATY, Philip B, SCHWARTZ, Gary K

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Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia von Lichtman, Aron H, Shelton, Christopher C, Advani, Tushar, Cravatt, Benjamin F

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Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors von WISE, Laura E, SHELTON, Christopher C, CRAVATT, Benjamin F, MARTIN, Billy R, LICHTMAN, Aron H

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A miniaturized 1536-well format gamma-secretase assay von Shelton, Christopher C, Tian, Yuan, Shum, David, Radu, Constantin, Djaballah, Hakim, Li, Yue-Ming

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Modulation of [gamma]-secretase specificity using small molecule allosteric inhibitors von Shelton, Christopher C, Zhu, Lei, Chau, Deming, Yang, Li, Wang, Rong, Djaballah, Hakim, Zheng, Hui, Li, Yue-Ming

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Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB 1 receptors von Wise, Laura E., Shelton, Christopher C., Cravatt, Benjamin F., Martin, Billy R., Lichtman, Aron H.

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Citizen Science Surveillance of Triazole-Resistant Aspergillus fumigatus in United Kingdom Residential Garden Soils von Shelton, Jennifer M G, Collins, Roseanna, Uzzell, Christopher B, Alghamdi, Asmaa, Dyer, Paul S, Singer, Andrew C, Fisher, Matthew C

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Germline Analysis from Tumor-Germline Sequencing Dyads to Identify Clinically Actionable Secondary Findings von Seifert, Bryce A, O'Daniel, Julianne M, Amin, Krunal, Marchuk, Daniel S, Patel, Nirali M, Parker, Joel S, Hoyle, Alan P, Mose, Lisle E, Marron, Andrew, Hayward, Michele C, Bizon, Christopher, Wilhelmsen, Kirk C, Evans, James P, Earp, 3rd, H Shelton, Sharpless, Norman E, Hayes, D Neil, Berg, Jonathan S

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Performance of the adaptive optics system for Laser Communications Relay Demonstration’s Ground Station 1 von Roberts, Lewis C., Meeker, Seth R., Tesch, Jonathan, Shelton, J. Christopher, Roberts, Jennifer E., Fregoso, Santos F., Troung, Tuan, Peng, Michael, Matthews, Kittrin, Herzog, Harrison, Rodriguez, Joshua

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A novel role for PGE2-EP4 in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function von Yarboro, Michael T, Boatwright, Naoko, Sekulich, Deanna C, Hooper, Christopher W, Wong, Ting, Poole, Stanley D, Berger, Courtney D, Brown, Alexus J, Jetter, Christopher S, Sucre, Jennifer M S, Shelton, Elaine L, Reese, Jeff

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A novel role for PGE 2 -EP 4 in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function von Yarboro, Michael T, Boatwright, Naoko, Sekulich, Deanna C, Hooper, Christopher W, Wong, Ting, Poole, Stanley D, Berger, Courtney D, Brown, Alexus J, Jetter, Christopher S, Sucre, Jennifer M S, Shelton, Elaine L, Reese, Jeff

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Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization von Sevcik, Molly A., Ghilardi, Joseph R., Peters, Christopher M., Lindsay, Theodore H., Halvorson, Kyle G., Jonas, Beth M., Kubota, Kazufumi, Kuskowski, Michael A., Boustany, Leila, Shelton, David L., Mantyh, Patrick W.

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Childhood trauma history differentiates amygdala response to sad faces within MDD von Grant, Merida M, Cannistraci, Christopher, Hollon, Steven D, Gore, John, Shelton, Richard

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Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero von Hooper, Christopher W, Delaney, Cassidy, Streeter, Taylor, Yarboro, Michael T, Poole, Stanley, Brown, Naoko, Slaughter, James C, Cotton, Robert B, Reese, Jeff, Shelton, Elaine L

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Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial von Aley, Parvinder K, Clutterbuck, Elizabeth A, Dold, Christina, Heath, Paul, Makinson, Rebecca, Pollock, Katrina M, Ramasamy, Maheshi, Robinson, Hannah, Douglas, Alexander D, Lambe, Teresa, Aboagye, Jeremy, Allen, Elizabeth, Anslow, Rachel, Baker, Philip, Bates, Louise, Batten, Alexander, Berry, Lisa, Beveridge, Amy, Bingham, Tracey, Brunt, Emily, Burbage, Jamie, Carroll, Miles W., Coombes, Naomi S., Cooper, Rachel, Crocker, Wendy E.M., Di Maso, Claudio, Dong, Tao, Douglas, Naomi, Downing, Charlotte, Elias, Sean C., Emary, Katherine R.W., Fletcher, Clare, Ford, Karen J., Fox, Polly, Frater, John, Galiza, Eva, Godwin, Kerry, Gorini, Giacomo, Goulston, Lyndsey, Gracie, Lara, Halwe, Sandro, Hamilton, Elizabeth, Hamlyn, Joseph, Harding, Irasha, Head, Ian, Hodgson, Susanne H.C., Howell, Nicola, Isitt, Catherine, Kailath, Reshma, Karampatsas, Konstantinos, Kerridge, Simon, Khan, Uzma, Kingham-Page, Lucy, Knott, Daniel, Koleva, Stanislava, Kupke, Alexandra, Lawrie, Alison M., Lee, Arlene, Lees, Emily A, Lias, Amelia M., Linder, Aline, Lopez Ramon, Raquel, Marlow, Emma, Marshall, Julia L., Meddaugh, Gretchen, Moore, Maria, Moran, Edward, Morris, Susan Jane, Morshead, Gertraud, Muller, Jilly, Munro, Alasdair, Noé, Andrés, O'Brien, Katie, O'Connor, Daniel, Oguti, Blanché, Oliver, Jennifer L., Osborn, Mairead, Pacurar, Mihaela, Pearce, Jennifer, Pfafferott, Katja, Poulton, Ian, Riddell, Amy, Sajjad, Sara, Sanders, Helen, Sanders, Katherine, Selby, Beatrice, Shelton, Holly, Song, Rinn, Stefanova, Elena, Tait, Moira, Talbot, Helen, Themistocleous, Yrene, Thomas, Merin, Towner, James, Turkentine, Kate, Turner, Sally, Veighey, Kristin, Vichos, Iason, Worth, Andrew T., Yau, Yasmine

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Loss of NFAT5 Results in Renal Atrophy and Lack of Tonicity-Responsive Gene Expression von López-Rodríguez, Cristina, Antos, Christopher L., Shelton, John M., Richardson, James A., Lin, Fangming, Novobrantseva, Tatiana I., Bronson, Roderick T., Igarashi, Peter, Rao, Anjana, Olson, Eric N.

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The effect of LRRK2 loss-of-function variants in humans von Whiffin, Nicola, Armean, Irina M., Kleinman, Aaron, Marshall, Jamie L., Minikel, Eric V., Goodrich, Julia K., Quaife, Nicholas M., Cole, Joanne B., Wang, Qingbo, Karczewski, Konrad J., Cummings, Beryl B., Francioli, Laurent, Laricchia, Kristen, Guan, Anna, Alipanahi, Babak, Morrison, Peter, Baptista, Marco A. S., Merchant, Kalpana M., Ware, James S., Havulinna, Aki S., Iliadou, Bozenna, Lee, Jung-Jin, Nadkarni, Girish N., Whiteman, Cole, Daly, Mark, Esko, Tõnu, Hultman, Christina, Loos, Ruth J. F., Milani, Lili, Palotie, Aarno, Pato, Carlos, Pato, Michele, Saleheen, Danish, Sullivan, Patrick F., Alföldi, Jessica, Cannon, Paul, MacArthur, Daniel G.

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Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial von Del Prato, Stefano, Pavo, Imre, Weerakkody, Govinda J, Yang, Zhengyu, Aizenberg, Diego, Wynne, Alan G, Wiese, Russell J, Arora, Samir, Calderon, Rafael B, Butuk, David J, Chaychi, Leila, Curtis, Brian M, Chochinov, Ronald, Chow, Christopher, Cone, Clancy L, Dungan, Kathleen, Gaudiani, Linda, Herandez-Vazquez, Luis, Hsia, Stanley H, Kutner, Mark E, Loy, Juan, Miranda, Francisco G, Oliver, Michael J, Parke, Michael T, Philis-Tsimikas, Athena, Rosenstock, Julio, Sorial, Ehab, Stonesifer, Larry D, Stringam, Stanley, Van, Joanna T, Vazquez-Tanus, Jose B, Reyes, Ramon, Karimjee, Najmuddin, Martin, Earl E, Fraser, Neil J, Bhargava, Anuj, Wynne, Alan G, Billings, Liana, Walsh, Patrick, Shubrook, Jay, Knouse, Albert B, Mayfield, Ronald K, Bitar, Fahed G, de la Cuesta, Carmen, Morales Portillo, Cristobal J, Quesada Charneco, Miguel, Tofe Povedano, Santiago, Vazquez, Luis, Soto Gonzalez, Alfonso, Ciomos, Daniela, Neacsu, Valentina, Stern, Naftali, Sofer, Yael, Sack, Jessica, Tirosh, Amir, Shehadeh, Naim, Darawsha, Mahmud, Skripova, Dasa, Pavleova, Eva, Kubincova, Ludmila, Merciakova, Martina, St-Amour, Eric, Yared, Zeina, Blouin, Francois, Aggarwal, Naresh K, Bajaj, Harpreet, Tailor, Chetna, Egan, Alan, St.Onge, Natasha, Borges, Joao L C, Franco, Denise R, Souza, Filipe D, Russo, Luis Augusto T, Sassone, Sonia A, Steinacher, Andrea, Perez Manghi, Federico C, Orio, Silvia I, Gelersztein, Elizabeth, Fretes, José O, Calella, Pedro R F, Zaidman, Cesar J, Chertkoff, Alejandro, Gonzalez Galvez, Guillermo, Calvo, Cesar G, Sowinski, Dariusz, Jozefowska, Malgorzata, Skokowska, Ewa, Modzelewska, Anna, Gilfillan, Christopher, Morbey, Claire, Kaur, Kamal, Kemp, Laurence, Shea, Antony J, Kunitsyna, Marina A, Ou, Horng-Yih, Chen, Jung-Fu, Hwu, Chii-Min, Doupis, John, Pagkalos, Emmanouil, Mouslech, Zadalla

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