Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV von Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.

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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis von Gralinski, Lisa E, Sheahan, Timothy P, Morrison, Thomas E, Menachery, Vineet D, Jensen, Kara, Leist, Sarah R, Whitmore, Alan, Heise, Mark T, Baric, Ralph S

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Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 von Walls, Alexandra C., Fiala, Brooke, Schäfer, Alexandra, Wrenn, Samuel, Pham, Minh N., Murphy, Michael, Tse, Longping V., Shehata, Laila, O’Connor, Megan A., Chen, Chengbo, Navarro, Mary Jane, Miranda, Marcos C., Pettie, Deleah, Ravichandran, Rashmi, Kraft, John C., Ogohara, Cassandra, Palser, Anne, Chalk, Sara, Lee, E-Chiang, Guerriero, Kathryn, Kepl, Elizabeth, Chow, Cameron M., Sydeman, Claire, Hodge, Edgar A., Brown, Brieann, Fuller, Jim T., Dinnon, Kenneth H., Gralinski, Lisa E., Leist, Sarah R., Gully, Kendra L., Lewis, Thomas B., Guttman, Miklos, Chu, Helen Y., Lee, Kelly K., Fuller, Deborah H., Baric, Ralph S., Kellam, Paul, Carter, Lauren, Pepper, Marion, Sheahan, Timothy P., Veesler, David, King, Neil P.

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Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid von Iserman, Christiane, Roden, Christine A., Boerneke, Mark A., Sealfon, Rachel S.G., McLaughlin, Grace A., Jungreis, Irwin, Fritch, Ethan J., Hou, Yixuan J., Ekena, Joanne, Weidmann, Chase A., Theesfeld, Chandra L., Kellis, Manolis, Troyanskaya, Olga G., Baric, Ralph S., Sheahan, Timothy P., Weeks, Kevin M., Gladfelter, Amy S.

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Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo von Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C C, Leist, Sarah R, Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Maison, Rachel M, Gazumyan, Anna, Martinez, David R, Baric, Ralph S, Robbiani, Davide F, Hatziioannou, Theodora, Ravetch, Jeffrey V, Bieniasz, Paul D, Bowen, Richard A, Nussenzweig, Michel C, Sheahan, Timothy P

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease von Agostini, Maria L, Andres, Erica L, Sims, Amy C, Graham, Rachel L, Sheahan, Timothy P, Lu, Xiaotao, Smith, Everett Clinton, Case, James Brett, Feng, Joy Y, Jordan, Robert, Ray, Adrian S, Cihlar, Tomas, Siegel, Dustin, Mackman, Richard L, Clarke, Michael O, Baric, Ralph S, Denison, Mark R

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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines von Walls, Alexandra C., Miranda, Marcos C., Schäfer, Alexandra, Pham, Minh N., Greaney, Allison, Arunachalam, Prabhu S., Navarro, Mary-Jane, Tortorici, M. Alejandra, Rogers, Kenneth, O’Connor, Megan A., Shirreff, Lisa, Ferrell, Douglas E., Bowen, John, Brunette, Natalie, Kepl, Elizabeth, Zepeda, Samantha K., Starr, Tyler, Hsieh, Ching-Lin, Fiala, Brooke, Wrenn, Samuel, Pettie, Deleah, Sydeman, Claire, Sprouse, Kaitlin R., Johnson, Max, Blackstone, Alyssa, Ravichandran, Rashmi, Ogohara, Cassandra, Carter, Lauren, Tilles, Sasha W., Rappuoli, Rino, Leist, Sarah R., Martinez, David R., Clark, Matthew, Tisch, Roland, O’Hagan, Derek T., Van Der Most, Robbert, Van Voorhis, Wesley C., Corti, Davide, McLellan, Jason S., Kleanthous, Harry, Sheahan, Timothy P., Smith, Kelly D., Fuller, Deborah H., Villinger, Francois, Bloom, Jesse, Pulendran, Bali, Baric, Ralph S., King, Neil P., Veesler, David

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SARS-like WIV1-CoV poised for human emergence von Menachery, Vineet D., Yount, Boyd L., Sims, Amy C., Debbink, Kari, Agnihothram, Sudhakar S., Gralinski, Lisa E., Graham, Rachel L., Scobey, Trevor, Plante, Jessica A., Royal, Scott R., Swanstrom, Jesica, Sheahan, Timothy P., Pickles, Raymond J., Corti, Davide, Randell, Scott H., Lanzavecchia, Antonio, Marasco, Wayne A., Baric, Ralph S.

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Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis von Leist, Sarah R, Jensen, Kara L, Baric, Ralph S, Sheahan, Timothy P

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Facile discovery of surrogate cytokine agonists von Yen, Michelle, Ren, Junming, Liu, Qingxiang, Glassman, Caleb R., Sheahan, Timothy P., Picton, Lora K., Moreira, Fernando R., Rustagi, Arjun, Jude, Kevin M., Zhao, Xiang, Blish, Catherine A., Baric, Ralph S., Su, Leon L., Garcia, K. Christopher

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Modeling hepatitis C virus infection using human induced pluripotent stem cells von Schwartz, Robert E, Trehan, Kartik, Andrus, Linda, Sheahan, Timothy P, Ploss, Alexander, Duncan, Stephen A, Rice, Charles M, Bhatia, Sangeeta N

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Hypergraph models of biological networks to identify genes critical to pathogenic viral response von Feng, Song, Heath, Emily, Jefferson, Brett, Joslyn, Cliff, Kvinge, Henry, Mitchell, Hugh D., Praggastis, Brenda, Eisfeld, Amie J., Sims, Amy C., Thackray, Larissa B., Fan, Shufang, Walters, Kevin B., Halfmann, Peter J., Westhoff-Smith, Danielle, Tan, Qing, Menachery, Vineet D., Sheahan, Timothy P., Cockrell, Adam S., Kocher, Jacob F., Stratton, Kelly G., Heller, Natalie C., Bramer, Lisa M., Diamond, Michael S., Baric, Ralph S., Waters, Katrina M., Kawaoka, Yoshihiro, McDermott, Jason E., Purvine, Emilie

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Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice von Martinez, David R., Schäfer, Alexandra, Leist, Sarah R., Li, Dapeng, Gully, Kendra, Yount, Boyd, Feng, Joy Y., Bunyan, Elaine, Porter, Danielle P., Cihlar, Tomas, Montgomery, Stephanie A., Haynes, Barton F., Baric, Ralph S., Nussenzweig, Michel C., Sheahan, Timothy P.

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Disparate SARS-CoV-2 infection outcomes abound, but what makes SARS-CoV-2 bound for rebound? von Sheahan, Timothy P

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A nano-luciferase expressing human coronavirus OC43 for countermeasure development von Diefenbacher, Meghan V., Baric, Thomas J., Martinez, David R., Baric, Ralph S., Catanzaro, Nicholas J., Sheahan, Timothy P.

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Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection von Powers, John M., Leist, Sarah R., Mallory, Michael L., Yount, Boyd L., Gully, Kendra L., Zweigart, Mark R., Bailey, Alexis B., Sheahan, Timothy P., Harkema, Jack R., Baric, Ralph S.

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An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo von Zhou, Nian E., Tang, Su, Bian, Xuelin, Parai, Maloy K., Krieger, Inna V., Flores, Armando, Jaiswal, Pradeep K., Bam, Radha, Wood, Jeremy L., Shi, Zhe, Stevens, Laura J., Scobey, Trevor, Diefenbacher, Meghan V., Moreira, Fernando R., Baric, Thomas J., Acharya, Arjun, Shin, Joonyoung, Rathi, Manish M., Wolff, Karen C., Riva, Laura, Bakowski, Malina A., McNamara, Case W., Catanzaro, Nicholas J., Graham, Rachel L., Schultz, David C., Cherry, Sara, Kawaoka, Yoshihiro, Halfmann, Peter J., Baric, Ralph S., Denison, Mark R., Sheahan, Timothy P., Sacchettini, James C.

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Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication von Adams, Lily E, Dinnon, 3rd, Kenneth H, Hou, Yixuan J, Sheahan, Timothy P, Heise, Mark T, Baric, Ralph S

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Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury von Sims, Amy C, Mitchell, Hugh D, Gralinski, Lisa E, Kyle, Jennifer E, Burnum-Johnson, Kristin E, Lam, Mariam, Fulcher, M Leslie, West, Ande, Smith, Richard D, Randell, Scott H, Metz, Thomas O, Sheahan, Timothy P, Waters, Katrina M, Baric, Ralph S

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A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans von Hanafin, Patrick O., Jermain, Brian, Hickey, Anthony J., Kabanov, Alexander V., Kashuba, Angela DM, Sheahan, Timothy P., Rao, Gauri G.

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