Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA von MacLachlan, Ian, Judge, Adam D, Sood, Vandana, Shaw, Janet R, Fang, Dianne, McClintock, Kevin

Volltext

Release of Cytochrome c, Bax Migration, Bid Cleavage, and Activation of Caspases 2, 3, 6, 7, 8, and 9 during Endothelial Cell Apoptosis von Granville, David J., Shaw, Janet R., Leong, Simon, Carthy, Christopher M., Margaron, Philippe, Hunt, David W., McManus, Bruce M.

Volltext

Allergy academy: a novel program for allergy nursing and clinic staff education von DeMuth, Karen A., BSN, MD, Kobrynski, Lisa, MD, MPH, Galina, Morton, MD, Chimento, J. Shannon, MSN, FNP-C, Shaw, Janet, RN, MBA, NE-BC

Volltext

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae von Yorimitsu, Tomohiro, Zaman, Shadia, Broach, James R, Klionsky, Daniel J

Volltext

Acute exacerbation of COPD von Ko, Fanny W., Chan, Ka Pang, Hui, David S., Goddard, John R., Shaw, Janet G., Reid, David W., Yang, Ian A.

Volltext

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score von Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M

Volltext

Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination von SCHACHE, Andrew G, LILOGLOU, Triantafilos, SLOAN, Philip, HARVEY-WOODWORTH, Colin, SISSON, Daniel, SHAW, Richard J, RISK, Janet M, FILIA, Anastasia, JONES, Terence M, SHEARD, Jon, WOOLGAR, Julia A, HELLIWELL, Timothy R, TRIANTAFYLLOU, Asterios, ROBINSON, Max

Volltext

Human innate immunosenescence: causes and consequences for immunity in old age von Panda, Alexander, Arjona, Alvaro, Sapey, Elizabeth, Bai, Fengwei, Fikrig, Erol, Montgomery, Ruth R, Lord, Janet M, Shaw, Albert C

Volltext

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve von Bairey Merz, C Noel, Handberg, Eileen M, Shufelt, Chrisandra L, Mehta, Puja K, Minissian, Margo B, Wei, Janet, Thomson, Louise E J, Berman, Daniel S, Shaw, Leslee J, Petersen, John W, Brown, Garrett H, Anderson, R David, Shuster, Jonathan J, Cook-Wiens, Galen, Rogatko, André, Pepine, Carl J

Volltext

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study von Knight, Stephen R, Holden, Karl A, Merson, Laura, Russell, Clark D, Solomon, Tom, Carson, Gail, Olliaro, Piero, Semple, Malcolm G, Alex, Beatrice, Bach, Benjamin, Dunning, Jake, da Silva Filipe, Ana, Horby, Peter W, Law, Andrew, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Scott, Janet T, de Silva, Thushan, Sigfrid, Louise, Tedder, Richard S, Thwaites, Ryan S, Turtle, Lance CW, Andrikopoulos, Petros, Liggi, Sonia, Sands, Caroline, Fairfield, Cameron J, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Hendry, Ross, Greenhalf, William, McDonald, Sarah E, Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Dincarslan, Oslem, Dyer, Philip, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Khandaker, Shadia, Lefteri, Daniella, Livoti, Lucia A, Middleton, Joanna, Reynolds, Will, Ridley, P. Matthew, Shaw, Victoria E, Tanianis-Hughes, Jolanta, Trochu, Erwan, Flaherty, Lisa, Massey, Hannah, Aldera, Erin L., Alegria, Ana, Barnass, Stella, Barrett, Nicholas, Basude, Sneha, Baxter, David, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Douthwaite, Sam, Fullerton, Duncan, Garg, Atul, Hawcutt, Daniel B, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Koduri, Gouri, Laird, Steven, Leiner, Tamas, Little, Jeff, McEwen, Ruth, Morris, Craig, Moses, Samuel, Norris, Lillian, Panchatsharam, Selva, Pattison, Natalie, Peters, Mark, Price, David, Prout, Rachel, Richardson, Neil, Rousseau, Guy, Ryan, Brendan, Sharma, Anil, Stambach, Tom, Stewart, Richard, Thompson, Robert, Tridente, Ascanio, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Wilson, Lawrence, Wiselka, Martin, Wootton, Daniel G, Workman, Andrew, Young, Peter

Volltext

SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses von Wang, Beibei, Skelly, Donal, Pan, Daniel, Omo-Dare, Nicola, Koeckerling, David, Jenkin, Daniel, Fernandes da Costa, Cristiano, Malik, Tariq, Baillie, J. Kenneth, Klenerman, Paul, Pollard, Andrew J., Conlon, Christopher, Jeffery, Katie, Stafford, Lizzie, Chand, Meera, Green, Christoper A., Harrison, Ewen M., Wai Ho, Antonia Ying, Palmarini, Massimo, Price, Nicholas, Robertson, David L., Sigfrid, Louise, Sriskandan, Shiranee, Stuart, David, Swann, Olivia V., Tedder, Richard S., Turtle, Lance CW, Zambon, Maria, Pius, Riinu, Knight, Stephen R., Harrison, Janet, Jackson, Clare, Gamble, Carrol, Plotkin, Daniel, Lee, James, Wham, Murray, Shaw, Victoria, McDonald, Sarah E., Armstrong, Jane A., Ashworth, Milton, Barlow, Samantha L., Bullock, Katie, Davis, Christopher, Dunn, Chris, King, Katharine, Kiy, Robyn T., Lant, Suzannah, Latawiec, Diane, Mancini, Maria, Metelmann, Soeren, Penrice-Randal, Rebekah, Pilgrim, Jack, van Tonder, Libby, Murphy, Lee, Morrice, Kirstie, Gilchrist, Tammy, Aldera, Erin L., Barnass, Stella, Bernatoniene, Jolanta, Bothma, Pieter, Brittain-Long, Robin, Caruth, Vikki, Collini, Paul, Dawson, Chris, Dervisevic, Samir, Dushianthan, Ahilanadan, Evans, Cariad, Harvey, Daniel, Hawcutt, Daniel B., Hodgson, Luke, Hormis, Anil, Kerrison, Caroline, Larkin, Susan, Little, Jeff, Meda, Manjula, Moon, James, Mortimore, Katherine, Murphy, Michael, O’Shea, Matthew K., Otahal, Igor, Panchatsharam, Selva, Patel, Brij, Pepperell, Justin, Peters, Mark, Price, David, Reschreiter, Henrik, Ruge, Bobby, Saluja, Taranprit, Sizer, Jeremy, Shankar-Hari, Manu, Snelson, Catherine, Staines, Nikki, Twagira, Mary, Vincent-Smith, Lisa, Visuvanathan, Shico, Welters, Ingeborg, Wolverson, Adam, Yates, Bryan, Fry, Elizabeth E., Ren, Jingshan

Volltext

Design tools for MPRA experiments von Ghazi, Andrew R, Chen, Edward S, Henke, David M, Madan, Namrata, Edelstein, Leonard C, Shaw, Chad A

Volltext

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease An International Multicenter Study von Drake, Thomas M., Docherty, Annemarie B., Harrison, Ewen M., Quint, Jennifer K., Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M., Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E., Dosanjh, Davinder, Fiddler, Christine A., Forrest, Ian A., George, Peter M., Gibbons, Michael A., Groom, Katherine, Haney, Sarah, Hart, Simon P., Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K., Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S., Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L., O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C., Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G., Stella, Giulia M., Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U., West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J. Kenneth, Openshaw, Peter J. M., Semple, Malcolm G., Stewart, Iain, Jenkins, R. Gisli

Volltext

Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis von Xiao, Junyu, Chen, Xiao-Wei, Davies, Brian A, Saltiel, Alan R, Katzmann, David J, Xu, Zhaohui

Volltext

Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction von Stub, Dion, Smith, Karen, Bernard, Stephen, Nehme, Ziad, Stephenson, Michael, Bray, Janet E, Cameron, Peter, Barger, Bill, Ellims, Andris H, Taylor, Andrew J, Meredith, Ian T, Kaye, David M

Volltext

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study von Docherty, Annemarie B, Jackson, Clare, Mclean, Kenneth A, Pritchard, Mark G, Russell, Clark D, Semple, Malcolm G, Semple, Malcolm G, Alex, Beatrice, Cooke, Graham S, Green, Christopher A, Ijaz, Samreen, Lim, Wei Shen, Meynert, Alison M, Paxton, William A, Robertson, David L, de Silva, Thushan, Sigfrid, Louise, Thwaites, Ryan S, Turtle, Lance CW, Drake, Tom M, Knight, Stephen, Plotkin, Daniel, Mullaney, Scott, Halpin, Sophie, Wham, Murray, Clohisey, Sara, Scott-Brown, James, Greenhalf, William, Asiimwe, Innocent G, Clark, Jordan J, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Latawiec, Diane, Lefteri, Daniella, Metelmann, Soeren, Middleton, Joanna, Sales, Debby, Shaw, Victoria E, Shears, Rebecca K, Tanianis-Hughes, Jolanta, Thomas, Jordan, Zhang, J. Eunice, Agranoff, Daniel, Agwuh, Ken, Angus, Brian, Bassford, Christopher, Bernatoniene, Jolanta, Berridge, John, Brealey, David, Burtenshaw, Andrew, Caruth, Vikki, Child, Jenny, Clark, Tom, Collini, Paul, Dawson, Chris, Dervisevic, Samir, Gkrania-Klotsas, Effrossyni, Godden, Jo, Goldsmith, Arthur, Hardy, Elaine, Harvey, Daniel, Hodgson, Luke, Jacobs, Michael, Kendall, Jason, Linnett, Vanessa, MacNaughton, Emily, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Morgan, Patrick, Nelson, Mark, Otahal, Igor, Paraiso, Hassan, Patel, Brij, Pattison, Natalie, Pepperell, Justin, Post, Frank, Price, David, Rae, Nikolas, Reynolds, Tim, Roberts, Mark, Sharma, Anil, Shankar-Hari, Manu, Stambach, Tom, Subudhi, Pradeep, Szakmany, Tamas, Thompson, Chris, Twagira, Mary, Ustianowski, Andrew, Vallotton, Nick, Vincent-Smith, Lisa, Welters, Ingeborg, Whitehouse, Tony, Williams, Martin, Wilson, Lawrence, Winchester, Stephen, Wolverson, Adam, Young, Peter

Volltext

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WH... von Bloom, Chloe I, Drake, Thomas M, Lipworth, Brian J, Johnston, Sebastian L, Nguyen-Van-Tam, Jonathan S, Carson, Gail, Semple, Malcolm G, Cullinan, Paul, Openshaw, Peter J M, Bach, Benjamin, Barclay, Wendy S, Chand, Meera, Fletcher, Tom, Khoo, Saye, Meynert, Alison M, Price, Nicholas, Robertson, David L, Sancho-Shimizu, Vanessa, Thomson, Emma C, Hardwick, Hayley, Oosthuyzen, Wilna, Pius, Riinu, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Clohisey, Sara, Hendry, Ross, Scott-Brown, James, Shaw, Victoria, McDonald, Sara, Ahmed, Katie A., Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Khandaker, Shadia, Lant, Suzannah, Lett, Lauren, McDonald, Sarah, McLauchlan, John, Penrice-Randal, Rebekah, Pilgrim, Jack, Wilcock, Eve, Carracedo, Alejandra Doce, Carlucci, Nicola, Holmes, Anthony, Agranoff, Daniel, Atkinson, Dougal, Barnass, Stella, Bassford, Christopher, Baxter, David, Beadsworth, Michael, Bothma, Pieter, Brittain-Long, Robin, Chambler, Duncan, Child, Jenny, Cupitt, Jason, Dark, Paul, Douthwaite, Sam, Dushianthan, Ahilanadan, Fullerton, Duncan, Hawcutt, Daniel B, Hormis, Anil, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kerslake, Ian, Koch, Oliver, Koshy, George, Laha, Shondipon, Limb, James, MacMahon, Michael, Matovu, Elijah, McEwen, Ruth, Mok, Quen, Mortimore, Katherine, Mpenge, Mbiye, Pais, Mark, Pepperell, Justin, Phull, Mandeep, Post, Frank, Reschreiter, Henrik, Roberts, Mark, Roberts, Devender, Rose, Alistair, Ryan, Brendan, Spittle, Nick, Thompson, Robert, Vuylsteke, Alan, Waddy, Sam, Whittaker, Paul, Whittington, Ashley, Wijesinghe, Meme, Wilson, Sarah, Wooton, Daniel G, Yates, Bryan

Volltext

An updated radiocarbon-based ice margin chronology for the last deglaciation of the North American Ice Sheet Complex von Dalton, April S., Margold, Martin, Stokes, Chris R., Tarasov, Lev, Dyke, Arthur S., Adams, Roberta S., Allard, Serge, Arends, Heather E., Atkinson, Nigel, Attig, John W., Barnett, Peter J., Barnett, Robert L., Batterson, Martin, Bernatchez, Pascal, Borns, Harold W., Breckenridge, Andy, Briner, Jason P., Brouard, Etienne, Campbell, Janet E., Carlson, Anders E., Clague, John J., Curry, B. Brandon, Daigneault, Robert-André, Dubé-Loubert, Hugo, Easterbrook, Don J., Franzi, David A., Friedrich, Hannah G., Funder, Svend, Gauthier, Michelle S., Gowan, Angela S., Harris, Ken L., Hétu, Bernard, Hooyer, Tom S., Jennings, Carrie E., Johnson, Mark D., Kehew, Alan E., Kelley, Samuel E., Kerr, Daniel, King, Edward L., Kjeldsen, Kristian K., Knaeble, Alan R., Lajeunesse, Patrick, Lakeman, Thomas R., Lamothe, Michel, Larson, Phillip, Lavoie, Martin, Loope, Henry M., Lowell, Thomas V., Lusardi, Barbara A., Manz, Lorraine, McMartin, Isabelle, Nixon, F. Chantel, Occhietti, Serge, Parkhill, Michael A., Piper, David J.W., Pronk, Antonius G., Richard, Pierre J.H., Ridge, John C., Ross, Martin, Roy, Martin, Seaman, Allen, Shaw, John, Stea, Rudolph R., Teller, James T., Thompson, Woodrow B., Thorleifson, L. Harvey, Utting, Daniel J., Veillette, Jean J., Ward, Brent C., Weddle, Thomas K., Wright, Herbert E.

Volltext

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... von Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

Volltext

Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial von Tauschmann, Martin, Thabit, Hood, Bally, Lia, Allen, Janet M, Hartnell, Sara, Wilinska, Malgorzata E, Ruan, Yue, Sibayan, Judy, Kollman, Craig, Cheng, Peiyao, Beck, Roy W, Acerini, Carlo L, Evans, Mark L, Dunger, David B, Elleri, Daniela, Campbell, Fiona, Bergenstal, Richard M, Criego, Amy, Shah, Viral N, Leelarathna, Lalantha, Hovorka, Roman, Alvarado, B, Ashanti, C, Baggott, J, Balakrishnan, K, Barber, N, Bath, L, Beasley, S, Beatson, C, Borgman, S, Bradshaw, S, Bugielski, B, Carlson, AB, Collett, E, Curtis, J, Demmitt, J, Donahue, D, Exall, J, Forshaw, R, Hayes, J, Heath, S, Hellmann, A, Huegel, V, Hyatt, J, James, L, Joseph, H, Joshee, P, Konerza, W, Lum, J, Madden, M, Martens, T, McCarthy, C, McDonald, M, Mikityuk, V, Miles, H, Miller, D, Mubita, W, Murphy, C, Olson, B, Pad, R, Patibandla, N, Riding, K, Shaju, A, Thomas, LA, Thomson, J, White, D, Yau, S, Yong, J

Volltext