Somatic mosaicism: implications for disease and transmission genetics von Campbell, Ian M, Shaw, Chad A, Stankiewicz, Pawel, Lupski, James R

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Host Transcriptional Response to Influenza and Other Acute Respiratory Viral Infections--A Prospective Cohort Study von Zhai, Yijie, Franco, Luis M, Atmar, Robert L, Quarles, John M, Arden, Nancy, Bucasas, Kristine L, Wells, Janet M, Niño, Diane, Wang, Xueqing, Zapata, Gladys E, Shaw, Chad A, Belmont, John W, Couch, Robert B

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation von Chambers, Stuart M, Shaw, Chad A, Gatza, Catherine, Fisk, C Joseph, Donehower, Lawrence A, Goodell, Margaret A

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MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome von Chen, Lin, Chen, Kaifu, Lavery, Laura A., Baker, Steven Andrew, Shaw, Chad A., Li, Wei, Zoghbi, Huda Y.

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Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B von Hause, Anne M, Henke, David M, Avadhanula, Vasanthi, Shaw, Chad A, Tapia, Lorena I, Piedra, Pedro A

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Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation von Posey, Jennifer E, Harel, Tamar, Liu, Pengfei, Rosenfeld, Jill A, James, Regis A, Coban Akdemir, Zeynep H, Walkiewicz, Magdalena, Bi, Weimin, Xiao, Rui, Ding, Yan, Xia, Fan, Beaudet, Arthur L, Muzny, Donna M, Gibbs, Richard A, Boerwinkle, Eric, Eng, Christine M, Sutton, V. Reid, Shaw, Chad A, Plon, Sharon E, Yang, Yaping, Lupski, James R

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Parent of Origin, Mosaicism, and Recurrence Risk: Probabilistic Modeling Explains the Broken Symmetry of Transmission Genetics von Campbell, Ian M., Stewart, Jonathan R., James, Regis A., Lupski, James R., Stankiewicz, Paweł, Olofsson, Peter, Shaw, Chad A.

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MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression von Teruel-Montoya, Raul, Kong, Xianguo, Abraham, Shaji, Ma, Lin, Kunapuli, Satya P, Holinstat, Michael, Shaw, Chad A, McKenzie, Steven E, Edelstein, Leonard C, Bray, Paul F

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Mus81 and converging forks limit the mutagenicity of replication fork breakage von Mayle, Ryan, Campbell, Ian M., Beck, Christine R., Yu, Yang, Wilson, Marenda, Shaw, Chad A., Bjergbaek, Lotte, Lupski, James R., Ira, Grzegorz

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A joint modeling approach for longitudinal microbiome data improves ability to detect microbiome associations with disease von Luna, Pamela N., Mansbach, Jonathan M., Shaw, Chad A.

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EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells von Neelakantan, Deepika, Zhou, Hengbo, Oliphant, Michael U. J., Zhang, Xiaomei, Simon, Lukas M., Henke, David M., Shaw, Chad A., Wu, Meng-Fen, Hilsenbeck, Susan G., White, Lisa D., Lewis, Michael T., Ford, Heide L.

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Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis von Crespo-Barreto, Juan, Fryer, John D, Shaw, Chad A, Orr, Harry T, Zoghbi, Huda Y

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A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis von Kessler, Jessica D., Kahle, Kristopher T., Sun, Tingting, Meerbrey, Kristen L., Schlabach, Michael R., Schmitt, Earlene M., Skinner, Samuel O., Xu, Qikai, Li, Mamie Z., Hartman, Zachary C., Rao, Mitchell, Yu, Peng, Dominguez-Vidana, Rocio, Liang, Anthony C., Solimini, Nicole L., Bernardi, Ronald J., Yu, Bing, Hsu, Tiffany, Golding, Ido, Luo, Ji, Osborne, C. Kent, Creighton, Chad J., Hilsenbeck, Susan G., Schiff, Rachel, Shaw, Chad A., Elledge, Stephen J., Westbrook, Thomas F.

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Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles von Coban-Akdemir, Zeynep, White, Janson J., Song, Xiaofei, Jhangiani, Shalini N., Fatih, Jawid M., Gambin, Tomasz, Bayram, Yavuz, Chinn, Ivan K., Karaca, Ender, Punetha, Jaya, Poli, Cecilia, Boerwinkle, Eric, Shaw, Chad A., Orange, Jordan S., Gibbs, Richard A., Lappalainen, Tuuli, Lupski, James R., Carvalho, Claudia M.B.

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A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models von XIAOMEI ZHANG, CLAERHOUT, Sofie, HELEN WONG, FUQUA, Suzanne W, CONTRERAS, Alejandro, GUTIERREZ, Carolina, JIAN HUANG, SUFENG MAO, PAVLICK, Anne C, FROEHLICH, Amber M, WU, Meng-Fen, TSIMELZON, Anna, PRATT, Aleix, HILSENBECK, Susan G, CHEN, Edward S, ZULOAGA, Pavel, SHAW, Chad A, RIMAWI, Mothaffar F, PEROU, Charles M, MILLS, Gordon B, CHANG, Jenny C, LEWIS, Michael T, DOBROLECKI, Lacey E, PETROVIC, Ivana, QING LAI, LANDIS, Melissa D, WIECHMANN, Lisa, SCHIFF, Rachel, GIULIANO, Mario

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A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection von Saxena, Kapil, Simon, Lukas M., Zeng, Xi-Lei, Blutt, Sarah E., Crawford, Sue E., Sastri, Narayan P., Karandikar, Umesh C., Ajami, Nadim J., Zachos, Nicholas C., Kovbasnjuk, Olga, Donowitz, Mark, Conner, Margaret E., Shaw, Chad A., Estes, Mary K.

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Respiratory syncytial virus and rhinovirus severe bronchiolitis are associated with distinct nasopharyngeal microbiota von Mansbach, Jonathan M., MD, MPH, Hasegawa, Kohei, MD, MPH, Henke, David M., MPH, Ajami, Nadim J., PhD, Petrosino, Joseph F., PhD, Shaw, Chad A., PhD, Piedra, Pedro A., MD, Sullivan, Ashley F., MS, MPH, Espinola, Janice A., MPH, Camargo, Carlos A., MD, DrPH, FAAAAI

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Non-invasive prenatal sequencing for multiple Mendelian monogenic disorders using circulating cell-free fetal DNA von Zhang, Jinglan, Li, Jianli, Saucier, Jennifer B., Feng, Yanming, Jiang, Yanjun, Sinson, Jefferson, McCombs, Anne K., Schmitt, Eric S., Peacock, Sandra, Chen, Stella, Dai, Hongzheng, Ge, Xiaoyan, Wang, Guoli, Shaw, Chad A., Mei, Hui, Breman, Amy, Xia, Fan, Yang, Yaping, Purgason, Anne, Pourpak, Alan, Chen, Zhao, Wang, Xia, Wang, Yue, Kulkarni, Shashikant, Choy, Kwong Wai, Wapner, Ronald J., Van den Veyver, Ignatia B., Beaudet, Arthur, Parmar, Sheetal, Wong, Lee-Jun, Eng, Christine M.

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Association of nasopharyngeal microbiota profiles with bronchiolitis severity in infants hospitalised for bronchiolitis von Hasegawa, Kohei, Mansbach, Jonathan M, Ajami, Nadim J, Espinola, Janice A, Henke, David M, Petrosino, Joseph F, Piedra, Pedro A, Shaw, Chad A, Sullivan, Ashley F, Camargo, Jr, Carlos A

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Identification of de novo copy number variants associated with human disorders of sexual development von Tannour-Louet, Mounia, Han, Shuo, Corbett, Sean T, Louet, Jean-Francois, Yatsenko, Svetlana, Meyers, Lindsay, Shaw, Chad A, Kang, Sung-Hae L, Cheung, Sau Wai, Lamb, Dolores J

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