Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers von Hu, Jiancheng, Stites, Edward C., Yu, Haiyang, Germino, Elizabeth A., Meharena, Hiruy S., Stork, Philip J.S., Kornev, Alexandr P., Taylor, Susan S., Shaw, Andrey S.

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Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury von Chung, Jun-Jae, Goldstein, Leonard, Chen, Ying-Jiun J, Lee, Jiyeon, Webster, Joshua D, Roose-Girma, Merone, Paudyal, Sharad C, Modrusan, Zora, Dey, Anwesha, Shaw, Andrey S

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Podocyte Aging: Why and How Getting Old Matters von Shankland, Stuart J, Wang, Yuliang, Shaw, Andrey S, Vaughan, Joshua C, Pippin, Jeffrey W, Wessely, Oliver

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Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling von Goncharov, Tatiana, Hedayati, Stefanie, Mulvihill, Melinda M., Izrael-Tomasevic, Anita, Zobel, Kerry, Jeet, Surinder, Fedorova, Anna V., Eidenschenk, Celine, deVoss, Jason, Yu, Kebing, Shaw, Andrey S., Kirkpatrick, Donald S., Fairbrother, Wayne J., Deshayes, Kurt, Vucic, Domagoj

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Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2 von Foster, Scott A., Whalen, Daniel M., Özen, Ayşegül, Wongchenko, Matthew J., Yin, JianPing, Yen, Ivana, Schaefer, Gabriele, Mayfield, John D., Chmielecki, Juliann, Stephens, Philip J., Albacker, Lee A., Yan, Yibing, Song, Kyung, Hatzivassiliou, Georgia, Eigenbrot, Charles, Yu, Christine, Shaw, Andrey S., Manning, Gerard, Skelton, Nicholas J., Hymowitz, Sarah G., Malek, Shiva

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An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development von Bagadia, Prachi, Huang, Xiao, Liu, Tian-Tian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschké, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M.

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The adaptor molecule CD2AP in CD4 T cells modulates differentiation of follicular helper T cells during chronic LCMV infection von Raju, Saravanan, Kometani, Kohei, Kurosaki, Tomohiro, Shaw, Andrey S, Egawa, Takeshi

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Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation von Blasius, Amanda L, Giurisato, Emanuele, Cella, Marina, Schreiber, Robert D, Shaw, Andrey S, Colonna, Marco

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Rac1 Activation in Podocytes Induces Rapid Foot Process Effacement and Proteinuria von Yu, Haiyang, Suleiman, Hani, Kim, Alfred H. J., Miner, Jeffrey H., Dani, Adish, Shaw, Andrey S., Akilesh, Shreeram

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Neonatal FcR Expression in Bone Marrow-Derived Cells Functions to Protect Serum IgG from Catabolism von Akilesh, Shreeram, Christianson, Gregory J, Roopenian, Derry C, Shaw, Andrey S

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Intravital and Kidney Slice Imaging of Podocyte Membrane Dynamics von Brähler, Sebastian, Yu, Haiyang, Suleiman, Hani, Krishnan, Gokul M, Saunders, Brian T, Kopp, Jeffrey B, Miner, Jeffrey H, Zinselmeyer, Bernd H, Shaw, Andrey S

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i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists von Romei, Matthew G., Leonard, Brandon, Katz, Zachary B., Le, Daniel, Yang, Yanli, Day, Eric S., Koo, Christopher W., Sharma, Preeti, Bevers III, Jack, Kim, Ingrid, Dai, Huiguang, Farahi, Farzam, Lin, May, Shaw, Andrey S., Nakamura, Gerald, Sockolosky, Jonathan T., Lazar, Greg A.

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Nanoscale protein architecture of the kidney glomerular basement membrane von Suleiman, Hani, Zhang, Lei, Roth, Robyn, Heuser, John E, Miner, Jeffrey H, Shaw, Andrey S, Dani, Adish

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New Lamp Posts Allow for New Views of the Immunological Synapse von Raju, Saravanan, Shaw, Andrey S.

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Albumin-associated free fatty acids induce macropinocytosis in podocytes von Chung, Jun-Jae, Huber, Tobias B, Gödel, Markus, Jarad, George, Hartleben, Björn, Kwoh, Christopher, Keil, Alexander, Karpitskiy, Aleksey, Hu, Jiancheng, Huh, Christine J, Cella, Marina, Gross, Richard W, Miner, Jeffrey H, Shaw, Andrey S

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Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade von Cruz Tleugabulova, Mayra, Melo, Sandra P., Wong, Aaron, Arlantico, Alexander, Liu, Meizi, Webster, Joshua D., Lau, Julia, Lechner, Antonie, Corak, Basak, Hodgins, Jonathan J., Garlapati, Venkata S., De Simone, Marco, Korin, Ben, Avraham, Shimrit, Lund, Jessica, Jeet, Surinder, Reiss, Alexander, Bender, Hannah, Austin, Cary D., Darmanis, Spyros, Modrusan, Zora, Brightbill, Hans, Durinck, Steffen, Diamond, Michael S., Schneider, Christoph, Shaw, Andrey S., Nitschké, Maximilian

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The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier von Schell, Christoph, Rogg, Manuel, Suhm, Martina, Helmstädter, Martin, Sellung, Dominik, Yasuda-Yamahara, Mako, Kretz, Oliver, Küttner, Victoria, Suleiman, Hani, Kollipara, Laxmikanth, Zahedi, René P., Sickmann, Albert, Eimer, Stefan, Shaw, Andrey S., Kramer-Zucker, Albrecht, Hirano-Kobayashi, Mariko, Abe, Takaya, Aizawa, Shinichi, Grahammer, Florian, Hartleben, Björn, Dengjel, Jörn, Huber, Tobias B.

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Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF von Hu, Jiancheng, Yu, Haiyang, Kornev, Alexandr P, Zhao, Jianping, Filbert, Erin L, Taylor, Susan S, Shaw, Andrey S

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Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W von Davies, Christopher W., Vidal, Simon E., Phu, Lilian, Sudhamsu, Jawahar, Hinkle, Trent B., Chan Rosenberg, Scott, Schumacher, Frances-Rose, Zeng, Yi Jimmy, Schwerdtfeger, Carsten, Peterson, Andrew S., Lill, Jennie R., Rose, Christopher M., Shaw, Andrey S., Wertz, Ingrid E., Kirkpatrick, Donald S., Koerber, James T.

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Podocytes use FcRn to clear IgG from the glomerular basement membrane von Akilesh, Shreeram, Huber, Tobias B, Wu, Hui, Wang, Gary, Hartleben, Björn, Kopp, Jeffrey B, Miner, Jeffrey H, Roopenian, Derry C, Unanue, Emil R, Shaw, Andrey S

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