The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma von Tian, Erming, Zhan, Fenghuang, Walker, Ronald, Rasmussen, Erik, Ma, Yupo, Barlogie, Bart, Shaughnessy, John D

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Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma von HOSE, Dirk, REME, Thierry, HILLENGASS, Jens, BERTSCH, Uta, NEBEN, Kai, MÖHLER, Thomas, ROSSI, Jean Francois, JAUCH, Anna, KLEIN, Bernard, GOLDSCHMIDT, Hartmut, HIELSCHER, Thomas, MOREAUX, Jérôme, MESSNER, Tobias, SECKINGER, Anja, BENNER, Axel, SHAUGHNESSY, John D, BARLOGIE, Bart, YIMING ZHOU

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CS1, a Potential New Therapeutic Antibody Target for the Treatment of Multiple Myeloma von Hsi, Eric D, Steinle, Roxanne, Balasa, Balaji, Szmania, Susann, Draksharapu, Aparna, Shum, Benny P, Huseni, Mahrukh, Powers, David, Nanisetti, Amulya, Zhang, Yin, Rice, Audie G, van Abbema, Anne, Wong, Melanie, Liu, Gao, Zhan, Fenghuang, Dillon, Myles, Chen, Shihao, Rhodes, Susan, Fuh, Franklin, Tsurushita, Naoya, Kumar, Shankar, Vexler, Vladimir, Shaughnessy, Jr, John D, Barlogie, Bart, van Rhee, Frits, Hussein, Mohamad, Afar, Daniel E H, Williams, Marna B

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The molecular characterization and clinical management of multiple myeloma in the post-genome era von Zhou, Y, Barlogie, B, Shaughnessy, J D

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F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma von Bartel, Twyla B., Haessler, Jeff, Brown, Tracy L.Y., Shaughnessy, John D., van Rhee, Frits, Anaissie, Elias, Alpe, Terri, Angtuaco, Edgardo, Walker, Ronald, Epstein, Joshua, Crowley, John, Barlogie, Bart

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Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo von Yaccoby, Shmuel, Ling, Wen, Zhan, Fenghuang, Walker, Ronald, Barlogie, Bart, Shaughnessy, John D.

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Inhibiting Dickkopf‐1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma von Heath, Deborah J, Chantry, Andrew D, Buckle, Clive H, Coulton, Les, Shaughnessy, John D, Evans, Holly R, Snowden, John A, Stover, David R, Vanderkerken, Karin, Croucher, Peter I

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The role of Dickkopf-1 in bone development, homeostasis, and disease von Pinzone, Joseph J., Hall, Brett M., Thudi, Nanda K., Vonau, Martin, Qiang, Ya-Wei, Rosol, Thomas J., Shaughnessy, John D.

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Magnetic Resonance Imaging in Multiple Myeloma: Diagnostic and Clinical Implications von WALKER, Ronald, BARLOGIE, Bart, CROWLEY, John, FERRIS, Ernest, HOLLMIG, Klaus, VAN RHEE, Frits, ZANGARI, Maurizio, PINEDA-ROMAN, Mauricio, MOHIUDDIN, Abid, YACCOBY, Shmuel, SAWYER, Jeffrey, ANGTUACO, Edgardo J, HAESSLER, Jeffrey, TRICOT, Guido, ANAISSIE, Elias, SHAUGHNESSY, John D, EPSTEIN, Joshua, VAN HEMERT, Rudy, ERDEM, Eren, HOERING, Antje

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Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma von Qiang, Ya-Wei, Barlogie, Bart, Rudikoff, Stuart, Shaughnessy, John D

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Infusion of haplo‐identical killer immunoglobulin‐like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation von Shi, Jumei, Tricot, Guido, Szmania, Susann, Rosen, Nancy, Garg, Tarun K., Malaviarachchi, Priyangi A., Moreno, Amberly, DuPont, Bo, Hsu, Katharine C., Baxter‐Lowe, Lee Ann, Cottler‐Fox, Michele, Shaughnessy Jr, John D., Barlogie, Bart, Van Rhee, Frits

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High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2 von Zhou, Yiming, Chen, Lijuan, Barlogie, Bart, Stephens, Owen, Wu, Xiaosong, Williams, David R, Cartron, Marie-Astrid, van Rhee, Frits, Nair, Bijay, Waheed, Sarah, Pineda-Roman, Mauricio, Alsayed, Yazan, Anaissie, Elias, Shaughnessy, John D. Jr

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Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outco... von Mohan, Meera, Gong, Zimu, Ashby, Timothy Cody, Al Hadidi, Samer, Thanendrarajan, Sharmilan, Schinke, Carolina, Alapat, Daisy, Shaughnessy, John D., Zhan, Fenghuang, Rhee, Frits, Sawyer, Jeffery R., Tian, Erming, Zangari, Maurizio

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Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth von Sun, Fumou, Cheng, Yan, Wanchai, Visanu, Guo, Wancheng, Mery, David, Xu, Hongwei, Gai, Dongzheng, Siegel, Eric, Bailey, Clyde, Ashby, Cody, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Ma, Yupo, Yi, Qing, Orlowski, Robert Z., Zangari, Maurizio, van Rhee, Frits, Janz, Siegfried, Bishop, Gail, Tricot, Guido, Shaughnessy, John D., Zhan, Fenghuang

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BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions von Sun, Fumou, Cheng, Yan, Chen, Jin-Ran, Wanchai, Visanu, Mery, David E, Xu, Hongwei, Gai, Dongzheng, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Tricot, Guido, Shaughnessy, Jr, John D, Zhan, Fenghuang

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The molecular classification of multiple myeloma von Zhan, Fenghuang, Huang, Yongsheng, Colla, Simona, Stewart, James P., Hanamura, Ichiro, Gupta, Sushil, Epstein, Joshua, Yaccoby, Shmuel, Sawyer, Jeffrey, Burington, Bart, Anaissie, Elias, Hollmig, Klaus, Pineda-Roman, Mauricio, Tricot, Guido, van Rhee, Frits, Walker, Ronald, Zangari, Maurizio, Crowley, John, Barlogie, Bart, Shaughnessy, John D.

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CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation von Gai, Dongzheng, Chen, Jin-Ran, Stewart, James P, Nookaew, Intawat, Habelhah, Hasem, Ashby, Cody, Sun, Fumou, Cheng, Yan, Li, Can, Xu, Hongwei, Peng, Bailu, Garg, Tarun K, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, Chen, Fangping, Barlogie, Bart, van Rhee, Frits, Tricot, Guido, Shaughnessy Jr., John D, Zhan, Fenghuang

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Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway von Knobloch, Jürgen, Shaughnessy, John D. Jr, Rüther, Ulrich

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High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients von Carrasco, Daniel R., Tonon, Giovanni, Huang, Yongsheng, Zhang, Yunyu, Sinha, Raktim, Feng, Bin, Stewart, James P., Zhan, Fenghuang, Khatry, Deepak, Protopopova, Marina, Protopopov, Alexei, Sukhdeo, Kumar, Hanamura, Ichiro, Stephens, Owen, Barlogie, Bart, Anderson, Kenneth C., Chin, Lynda, Shaughnessy, John D., Brennan, Cameron, DePinho, Ronald A.

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A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1 von Shaughnessy, John D., Zhan, Fenghuang, Burington, Bart E., Huang, Yongsheng, Colla, Simona, Hanamura, Ichiro, Stewart, James P., Kordsmeier, Bob, Randolph, Christopher, Williams, David R., Xiao, Yan, Xu, Hongwei, Epstein, Joshua, Anaissie, Elias, Krishna, Somashekar G., Cottler-Fox, Michele, Hollmig, Klaus, Mohiuddin, Abid, Pineda-Roman, Mauricio, Tricot, Guido, van Rhee, Frits, Sawyer, Jeffrey, Alsayed, Yazan, Walker, Ronald, Zangari, Maurizio, Crowley, John, Barlogie, Bart

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