Stem and progenitor cell alterations in myelodysplastic syndromes von Shastri, Aditi, Will, Britta, Steidl, Ulrich, Verma, Amit

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IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells von Schinke, Carolina, Giricz, Orsolya, Li, Weijuan, Shastri, Aditi, Gordon, Shanisha, Barreyro, Laura, Bhagat, Tushar, Bhattacharyya, Sanchari, Ramachandra, Nandini, Bartenstein, Matthias, Pellagatti, Andrea, Boultwood, Jacqueline, Wickrema, Amittha, Yu, Yiting, Will, Britta, Wei, Sheng, Steidl, Ulrich, Verma, Amit

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ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine von Rahmani, Nora E., Ramachandra, Nandini, Sahu, Srabani, Gitego, Nadege, Lopez, Andrea, Pradhan, Kith, Bhagat, Tushar D., Gordon-Mitchell, Shanisha, Pena, Bianca Rivera, Kazemi, Mohammad, Rao, Keshav, Giricz, Orsi, Maqbool, Shahina Bano, Olea, Raul, Zhao, Yongmei, Zhang, Jinghang, Dolatshad, Hamid, Tittrea, Vickram, Tatwavedi, Dharamveer, Singh, Shalini, Lee, Juseong, Sun, Tianyu, Steidl, Ulrich, Shastri, Aditi, Inoue, Daichi, Abdel-Wahab, Omar, Pellagatti, Andrea, Gavathiotis, Evripidis, Boultwood, Jacqueline, Verma, Amit

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North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies von Shah, Urvi A., Chung, Elaine Y., Giricz, Orsi, Pradhan, Kith, Kataoka, Keisuke, Gordon-Mitchell, Shanisha, Bhagat, Tushar D., Mai, Yun, Wei, Yongqiang, Ishida, Elise, Choudhary, Gaurav S., Joseph, Ancy, Rice, Ronald, Gitego, Nadege, Parrish, Crystall, Bartenstein, Matthias, Goel, Swati, Mantzaris, Ioannis, Shastri, Aditi, Derman, Olga, Binder, Adam, Gritsman, Kira, Kornblum, Noah, Braunschweig, Ira, Bhagat, Chirag, Hall, Jeff, Graber, Armin, Ratner, Lee, Wang, Yanhua, Ogawa, Seishi, Verma, Amit, Ye, B. Hilda, Janakiram, Murali

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Therapeutic targeting of the inflammasome in myeloid malignancies von Chakraborty, Samarpana, Shapiro, Lauren C., de Oliveira, Sofia, Rivera-Pena, Bianca, Verma, Amit, Shastri, Aditi

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Impact of race and ethnicity on early mortality in multiple myeloma: a SEER analysis von Wei, John X, Shastri, Aditi, Sica, R Alejandro, Mantzaris, Ioannis, Kornblum, Noah, Shah, Urvi, Janakiram, Murali, Gritsman, Kira, Verma, Amit, Goldfinger, Mendel, Cooper, Dennis, Shah, Nishi

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Axicabtagene ciloleucel CD19 CAR-T cell therapy results in high rates of systemic and neurologic remissions in ten patients with refractory large B cell lymphoma including two with... von Abbasi, Ahmed, Peeke, Stephen, Shah, Nishi, Mustafa, Jennat, Khatun, Fariha, Lombardo, Amanda, Abreu, Michelly, Elkind, Richard, Fehn, Karen, de Castro, Alyssa, Wang, Yanhua, Derman, Olga, Nelson, Randin, Uehlinger, Joan, Gritsman, Kira, Sica, R. Alejandro, Kornblum, Noah, Mantzaris, Ioannis, Shastri, Aditi, Janakiram, Murali, Goldfinger, Mendel, Verma, Amit, Braunschweig, Ira, Bachier-Rodriguez, Lizamarie

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Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations von Choudhary, Gaurav S, Pellagatti, Andrea, Agianian, Bogos, Smith, Molly A, Bhagat, Tushar D, Gordon-Mitchell, Shanisha, Sahu, Srabani, Pandey, Sanjay, Shah, Nishi, Aluri, Srinivas, Aggarwal, Ritesh, Aminov, Sarah, Schwartz, Leya, Steeples, Violetta, Booher, Robert N, Ramachandra, Murali, Samson, Maria, Carbajal, Milagros, Pradhan, Kith, Bowman, Teresa V, Pillai, Manoj M, Will, Britta, Wickrema, Amittha, Shastri, Aditi, Bradley, Robert K, Martell, Robert E, Steidl, Ulrich G, Gavathiotis, Evripidis, Boultwood, Jacqueline, Starczynowski, Daniel T, Verma, Amit

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High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster von Jasra, Sakshi, Giricz, Orsi, Zeig-Owens, Rachel, Pradhan, Kith, Goldfarb, David G., Barreto-Galvez, Angelica, Silver, Alexander J., Chen, Jiahao, Sahu, Srabani, Gordon-Mitchell, Shanisha, Choudhary, Gaurav S., Aluri, Srinivas, Bhagat, Tushar D., Shastri, Aditi, Bejan, Cosmin A., Stockton, Shannon S., Spaulding, Travis P., Thiruthuvanathan, Victor, Goto, Hiroki, Gerhardt, Jeannine, Haider, Syed Hissam, Veerappan, Arul, Bartenstein, Matthias, Nwankwo, George, Landgren, Ola, Weiden, Michael D., Lekostaj, Jacqueline, Bender, Ryan, Fletcher, Frederick, Greenberger, Lee, Ebert, Benjamin L., Steidl, Ulrich, Will, Britta, Nolan, Anna, Madireddy, Advaitha, Savona, Michael R., Prezant, David J., Verma, Amit

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Myelodysplastic syndromes and the risk of cardiovascular disease in older adults: A SEER-medicare analysis von Adrianzen Herrera, Diego, Pradhan, Kith, Snyder, Rose, Karanth, Siddharth, Janakiram, Murali, Mantzaris, Ioannis, Braunschweig, Ira, Budhathoki, Anjali, Shah, Urvi A., Verma, Amit K., Murthy, Santosh B., Shastri, Aditi

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A case series of Monoclonal Gammopathy of Undetermined Significance and COVID‐19 von Gonzalez‐Lugo, Jesus D., Bachier‐Rodriguez, Lizamarie, Goldfinger, Mendel, Shastri, Aditi, Sica, R. Alejandro, Gritsman, Kira, Mehta, Vikas, Kabarriti, Rafi, Goel, Sanjay, Verma, Amit, Braunschweig, Ira, Kornblum, Noah, Mantzaris, Ioannis

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Autologous stem cell transplantation in an older adult population von Fedorov, Kateryna, Jain, Tanim, Pradhan, Kith, Mustafa, Jennat, Lombardo, Amanda, Khatun, Fariha, Joseph, Felisha, Gillick, Kailyn, Naik, Anjali, Elkind, Richard, Fehn, Karen, De Castro, Alyssa, Browne, Roy, Abreu, Michelly, Binakaj, Donika, Paroder, Monika, Palesi, Carlo, Gritsman, Kira, Sica, R Alejandro, Kornblum, Noah, Shastri, Aditi, Mantzaris, Ioannis, Shah, Nishi, Verma, Amit, Braunschweig, Ira, Goldfinger, Mendel

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Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer von Zhang, Yang, Chen, Xiaoyi, Wang, Huamin, Gordon-Mitchell, Shanisha, Sahu, Srabani, Bhagat, Tushar D, Choudhary, Gaurav, Aluri, Srinivas, Pradhan, Kith, Sahu, Plabani, Carbajal, Milagros, Zhang, Hui, Agarwal, Beamon, Shastri, Aditi, Martell, Robert, Starczynowski, Daniel, Steidl, Ulrich, Maitra, Anirban, Verma, Amit

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Safety of axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma in an elderly intercity population von Shapiro, Lauren C., Mustafa, Jennat, Lombardo, Amanda, Khatun, Fariha, Joseph, Felisha, Gillick, Kailyn, Naik, Anjali, Elkind, Richard, Abreu, Michelly, Fehn, Karen, de Castro, Alyssa, Pradhan, Kith, Binakaj, Donika, Nelson, Randin, Paroder, Monika, Uehlinger, Joan, Gritsman, Kira, Alejandro Sica, R., Kornblum, Noah, Shastri, Aditi, Mantzaris, Ioannis, Bachier-Rodriguez, Lizamarie, Verma, Amit, Braunschweig, Ira, Goldfinger, Mendel

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Elevated LDH greater than 400 U/L portends poorer overall survival in diffuse large B-cell lymphoma patients treated with CD19 CAR-T cell therapy in a real world multi-ethnic cohor... von Rabinovich, Emma, Pradhan, Kith, Sica, R. Alejandro, Bachier-Rodriguez, Lizamarie, Mantzaris, Ioannis, Kornblum, Noah, Shastri, Aditi, Gritsman, Kira, Goldfinger, Mendel, Verma, Amit, Braunschweig, Ira

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Correction: Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer von Zhang, Yang, Chen, Xiaoyi, Wang, Huamin, Gordon-Mitchell, Shanisha, Sahu, Srabani, Bhagat, Tushar D, Choudhary, Gaurav, Aluri, Srinivas, Pradhan, Kith, Sahu, Plabani, Carbajal, Milagros, Zhang, Hui, Agarwal, Beamon, Shastri, Aditi, Martell, Robert, Starczynowski, Daniel, Steidl, Ulrich, Maitra, Anirban, Verma, Amit

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Neural Mechanisms of Positive Mood Induced Modulation of Reality Monitoring von Subramaniam, Karuna, Gill, Jeevit, Slattery, Patrick, Shastri, Aditi, Mathalon, Daniel H, Nagarajan, Srikantan, Vinogradov, Sophia

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Role of innate immunological/inflammatory pathways in myelodysplastic syndromes and AML: a narrative review von Vegivinti, Charan Thej Reddy, Keesari, Praneeth Reddy, Veeraballi, Sindhusha, Martins Maia, Catarina Maria Pina, Mehta, Ansh Krishnachandra, Lavu, Rohit Reddy, Thakur, Rahul Kumar, Tella, Sri Harsha, Patel, Riya, Kakumani, Venkata Kiranmayi, Pulakurthi, Yashwitha Sai, Aluri, Srinivas, Aggarwal, Ritesh Kumar, Ramachandra, Nandini, Zhao, Rongbao, Sahu, Srabani, Shastri, Aditi, Verma, Amit

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P488: SAFETY AND EFFICACY OF VENETOCLAX PLUS “7 + 3” CHEMOTHERAPY IN NEWLY DIAGNOSED AML von Mantzaris, Ioannis, Goldfinger, Mendel, Levitz, David, Fedorov, Kateryna, Munoz, Annemarie, Chambers, Nicole, Fehn, Karen, Dhawan, Aradhika, Victor, Joel, Shah, Nishi, Shastri, Aditi, Kornblum, Noah, Sica, Alejandro, Gritsman, Kira, Cooper, Dennis, Kim, Mimi, Verma, Amit K., Steidl, Ulrich, Feldman, Eric, Konopleva, Marina

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P697: DISTINCT SPLICING ALTERATIONS ASSOCIATED WITH CLINICAL RESPONSE TO LUSPATERCEPT IN PATIENTS WITH LOWER‑RISK MYELODYSPLASTIC SYNDROMES FROM THE MEDALIST STUDY von Aluri, Srinivas, Ahsan, Aarif, Hayati, Sheida, Ugidos, Manuel, Shah, Punit, Lizotte, Kate, Chakraborty, Samarpana, Pradhan, Kith, Sahu, Srabani, Maqbool, Shahina, Shastri, Aditi, Dongre, Ashok, Platzbecker, Uwe, Gandhi, Anita, Nvs Suragani, Rajasekhar, Vodala, Sadanand, Verma, Amit

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