Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease von Tufarelli, Cristina, Stanley, Jackie A Sloane, Garrick, David, Sharpe, Jackie A, Ayyub, Helena, Wood, William G, Higgs, Douglas R

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Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues von Garrick, David, Sharpe, Jackie A, Arkell, Ruth, Dobbie, Lorraine, Smith, Andrew J H, Wood, William G, Higgs, Douglas R, Gibbons, Richard J

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Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence von Wallace, Helen A.C., Marques-Kranc, Fatima, Richardson, Melville, Luna-Crespo, Francisco, Sharpe, Jackie A., Hughes, Jim, Wood, William G., Higgs, Douglas R., Smith, Andrew J.H.

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A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype von PRITCHARD, Lynn, SLOANE-STANLEY, Jackie A, JING ZHOU, WOOD, William G, HARRIS, Peter C, SHARPE, Jackie A, ASPINWALL, Richard, WEINING LU, BUCKLE, Veronica, STRMECKI, Lana, WALKER, Denise, WARD, Christopher J, ALPERS, Charles E

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Safer Prescribing for Hospitalized Older Adults with an Electronic Health Records‐Based Prescribing Context von Drago, Kathleen, Sharpe, Jackie, De Lima, Bryanna, Alhomod, Abdulaziz, Eckstrom, Elizabeth

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In Pursuit of the Quadruple Aim: A Geriatric Prescribing Context’s Impact on Clinician Workflows and Alert Fatigue von Drago, Kathleen, De Lima, Bryanna, Sharpe, Jackie, Eckstrom, Elizabeth

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An intronic Runx1 enhancer directs transcription to the emerging hematopoietic system of the mouse embryo von Nottingham, Wade, Burgess, Matthew, Speck, Caroline, Barton, Debbie, Kong-a-san, John, Li, Pik-Shan, Sloane-Stanley, Jackie, Sharpe, Jackie, de Bruijn, Marella

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The mechanism of alpha-globin activation during erythropoiesis von Higgs, Doug, Vernimmen, Doug, Ayyub, Helena, De Gobbi, Marco, Hughes, Jim, Dunham, Ian, Koch, Christoph, Buckle, Veronica, Iborra, Francisco, Brown, Jill, Sharpe, Jackie, Sloane-Stanley, Jackie, Gibbons, Richard, Wood, Bill

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Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues von David Garrick, Jackie A Sharpe, Ruth Arkell, Lorraine Dobbie, Andrew J H Smith, William G Wood, Douglas R Higgs, Richard J Gibbons

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Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia von Mettananda, Sachith, Fisher, Chris A., Hay, Deborah, Badat, Mohsin, Quek, Lynn, Clark, Kevin, Hublitz, Philip, Downes, Damien, Kerry, Jon, Gosden, Matthew, Telenius, Jelena, Sloane-Stanley, Jackie A., Faustino, Paula, Coelho, Andreia, Doondeea, Jessica, Usukhbayar, Batchimeg, Sopp, Paul, Sharpe, Jacqueline A., Hughes, Jim R., Vyas, Paresh, Gibbons, Richard J., Higgs, Douglas R.

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The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats von Nguyen, Diu TT, Voon, Hsiao Phin J, Xella, Barbara, Scott, Caroline, Clynes, David, Babbs, Christian, Ayyub, Helena, Kerry, Jon, Sharpe, Jacqueline A, Sloane‐Stanley, Jackie A, Butler, Sue, Fisher, Chris A, Gray, Nicki E, Jenuwein, Thomas, Higgs, Douglas R, Gibbons, Richard J

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A Randomized Trial of Progesterone in Women with Recurrent Miscarriages von Coomarasamy, Arri, Williams, Helen, Truchanowicz, Ewa, Seed, Paul T, Small, Rachel, Quenby, Siobhan, Gupta, Pratima, Dawood, Feroza, Koot, Yvonne E.M, Bender Atik, Ruth, Bloemenkamp, Kitty W.M, Brady, Rebecca, Briley, Annette L, Cavallaro, Rebecca, Cheong, Ying C, Chu, Justin J, Eapen, Abey, Ewies, Ayman, Hoek, Annemieke, Kaaijk, Eugenie M, Koks, Carolien A.M, Li, Tin-Chiu, MacLean, Marjory, Mol, Ben W, Moore, Judith, Ross, Jackie A, Sharpe, Lisa, Stewart, Jane, Vaithilingam, Nirmala, Farquharson, Roy G, Kilby, Mark D, Khalaf, Yacoub, Goddijn, Mariette, Regan, Lesley, Rai, Rajendra

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PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicen... von Coomarasamy, Arri, Williams, Helen, Truchanowicz, Ewa, Seed, Paul T, Small, Rachel, Quenby, Siobhan, Gupta, Pratima, Dawood, Feroza, Koot, Yvonne E, Atik, Ruth Bender, Bloemenkamp, Kitty Wm, Brady, Rebecca, Briley, Annette, Cavallaro, Rebecca, Cheong, Ying C, Chu, Justin, Eapen, Abey, Essex, Holly, Ewies, Ayman, Hoek, Annemieke, Kaaijk, Eugenie M, Koks, Carolien A, Li, Tin-Chiu, MacLean, Marjory, Mol, Ben W, Moore, Judith, Parrott, Steve, Ross, Jackie A, Sharpe, Lisa, Stewart, Jane, Trépel, Dominic, Vaithilingam, Nirmala, Farquharson, Roy G, Kilby, Mark David, Khalaf, Yacoub, Goddijn, Mariëtte, Regan, Lesley, Rai, Rajendra

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Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom von Török, M Estée, Underwood, Benjamin R, Toshner, Mark, Waddington, Claire, Sidhom, Emad, Sharrocks, Katherine, Bousfield, Rachel, Summers, Charlotte, Saunders, Caroline, McIntyre, Zoe, Morris, Helen, Piper, Jo, Calderon, Gloria, Dennis, Sarah, Assari, Tracy, de Rotrou, Anita Marguerie, Shaw, Ashley, Bradley, John, O’Brien, John, Rintoul, Robert C, Smith, Ian, Bullmore, Ed, Chatterjee, Krishna, Ribeiro, Carla, Pickup, Lorinda, de Jesus, Ranalie, Brookes, Karen, Vargas, Phoebe, McMahon, Caroline, Macor, Chiara, Pasquale, Ciro, Bermperi, Areti, Kourampa, Evgenia, Fabiculcana, Marivic, Zerudo, Julie Ann, Mendoza, Vivien, Fuller, Stewart, Glemas, Claire, Baker, Sharon, Lyons, Greta, Bishop, Marina, Coleman, Siobhan, Thomas, Naomi, Mlilo, Vince, Stanton, Edward, Michel, Rachel, Philips, Julie, Rice, Heidi, Garner, Lucie, Rosa, Francesca, Victor, Saji, Zamikula, Julie, Mepham, Sue, Hajee, Fatima, Quijano-Campos, Juan Carlos, Watson, Laura, Georgiou, Christopher, Worsley, Jieniean, Shamtally-Amode, Djamilla, Rahimi, Ferishta, Jones, Heather, Cruz, Isabel, Lindsay, Gayle, Sparke, Christian, Chapman, Anna, Keating-Fedders, Katie, Fahey, Codie, Johnson, Danielle, Worboys, Lucy, Hargreaves, Simone, Bucke, Ashlea, Carr, Lindsay, Hampshire, Jackie, Richardson, Tracy, Sharpe, Jenny, Whitehead, Lynne, Vyse, Naval, Kelleher, Stephen, Sherwood, Mary-Beth, Hughes, Vicki, Giraud, Kim

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A Randomized Trial of Progesterone in Women with Recurrent Miscarriages von Coomarasamy, Arri, Williams, Helen, Truchanowicz, Ewa, Seed, Paul T, Small, Rachel, Quenby, Siobhan, Gupta, Pratima, Dawood, Feroza, Koot, Yvonne E M, Bender Atik, Ruth, Bloemenkamp, Kitty W M, Brady, Rebecca, Briley, Annette L, Cavallaro, Rebecca, Cheong, Ying C, Chu, Justin J, Eapen, Abey, Ewies, Ayman, Hoek, Annemieke, Kaaijk, Eugenie M, Koks, Carolien A M, Li, Tin-Chiu, MacLean, Marjory, Mol, Ben W, Moore, Judith, Ross, Jackie A, Sharpe, Lisa, Stewart, Jane, Vaithilingam, Nirmala, Farquharson, Roy G, Kilby, Mark D, Khalaf, Yacoub, Goddijn, Mariette, Regan, Lesley, Rai, Rajendra

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PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicen... von Coomarasamy, Arri, Williams, Helen, Truchanowicz, Ewa, Seed, Paul T, Small, Rachel, Quenby, Siobhan, Gupta, Pratima, Dawood, Feroza, Koot, Yvonne E, Atik, Ruth Bender, Bloemenkamp, Kitty Wm, Brady, Rebecca, Briley, Annette, Cavallaro, Rebecca, Cheong, Ying C, Chu, Justin, Eapen, Abey, Essex, Holly, Ewies, Ayman, Hoek, Annemieke, Kaaijk, Eugenie M, Koks, Carolien A, Li, Tin-Chiu, MacLean, Marjory, Mol, Ben W, Moore, Judith, Parrott, Steve, Ross, Jackie A, Sharpe, Lisa, Stewart, Jane, Trépel, Dominic, Vaithilingam, Nirmala, Farquharson, Roy G, Kilby, Mark David, Khalaf, Yacoub, Goddijn, Mariëtte, Regan, Lesley, Rai, Rajendra

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Assessment of the Robustness of a Serendipitous Zinc Binding Fold: Mutagenesis and Protein Grafting von Sharpe, Belinda K., Liew, Chu Kong, Kwan, Ann H., Wilce, Jackie A., Crossley, Merlin, Matthews, Jacqueline M., Mackay, Joel P.

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Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia von Mettananda, Sachith, Fisher, Chris A., Hay, Deborah, Badat, Mohsin, Quek, Lynn, Clark, Kevin, Hublitz, Philip, Downes, Damien, Kerry, Jon, Gosden, Matthew, Telenius, Jelena, Sloane-Stanley, Jackie A., Faustino, Paula, Coelho, Andreia, Doondeea, Jessica, Usukhbayar, Batchimeg, Sopp, Paul, Sharpe, Jacqueline A., Hughes, Jim R., Vyas, Paresh, Gibbons, Richard J., Higgs, Douglas R.

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Analysis of DNA Methylation at the Human Alpha Globin Cluster during Hematopoiesis von Ekwattanakit, Supachai, Ayyub, Helena, Clark, Kevin, Marques-Kranc, Fatima, Butler, Sue, Sloane-Stanley, Jackie, Sharpe, Jacqueline A, Colella, Stefano, Ragoussis, Jiannis, Viprakasit, Vip, Gibbons, Richard J, Higgs, Douglas R

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PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicen... von Coomarasamy, Arri, Williams, Helen, Truchanowicz, Ewa, Seed, Paul T, Small, Rachel, Quenby, Siobhan, Gupta, Pratima, Dawood, Feroza, Koot, Yvonne E, Atik, Ruth Bender, Bloemenkamp, Kitty Wm, Brady, Rebecca, Briley, Annette, Cavallaro, Rebecca, Cheong, Ying C, Chu, Justin, Eapen, Abey, Essex, Holly, Ewies, Ayman, Hoek, Annemieke, Kaaijk, Eugenie M, Koks, Carolien A, Li, Tin-Chiu, MacLean, Marjory, Mol, Ben W, Moore, Judith, Parrott, Steve, Ross, Jackie A, Sharpe, Lisa, Stewart, Jane, Trépel, Dominic, Vaithilingam, Nirmala, Farquharson, Roy G, Kilby, Mark David, Khalaf, Yacoub, Goddijn, Mariëtte, Regan, Lesley, Rai, Rajendra

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