Development and validation of a stereoselective liquid chromatography–tandem mass spectrometry assay for quantification of S- and R-metoprolol in human plasma von Jensen, Berit P., Sharp, Caroline F., Gardiner, Sharon J., Begg, Evan J.

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Deep tissue scattering compensation with three-photon F-SHARP von Berlage, Caroline, Tantirigama, Malinda L. S., Babot, Mathias, Di Battista, Diego, Whitmire, Clarissa, Papadopoulos, Ioannis N., Poulet, James F. A., Larkum, Matthew, Judkewitz, Benjamin

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Effectiveness and cost-effectiveness of the GoActive intervention to increase physical activity among UK adolescents: A cluster randomised controlled trial von Corder, Kirsten, Sharp, Stephen J, Jong, Stephanie T, Foubister, Campbell, Brown, Helen Elizabeth, Wells, Emma K, Armitage, Sofie M, Croxson, Caroline H D, Vignoles, Anna, Wilkinson, Paul O, Wilson, Edward C F, van Sluijs, Esther M F

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The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs von Arieti, Fabiana, Gabus, Caroline, Tambalo, Margherita, Huet, Tiphaine, Round, Adam, Thore, Stéphane

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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind st... von Long, Georgina V, Prof, Dummer, Reinhard, Prof, Hamid, Omid, MD, Gajewski, Thomas F, Prof, Caglevic, Christian, MD, Dalle, Stephane, Prof, Arance, Ana, MD, Carlino, Matteo S, PhD, Grob, Jean-Jacques, Prof, Kim, Tae Min, Prof, Demidov, Lev, Prof, Robert, Caroline, Prof, Larkin, James, Prof, Anderson, James R, PhD, Maleski, Janet, BSN, Jones, Mark, MD, Diede, Scott J, MD, Mitchell, Tara C, MD

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Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial von Ribas, Antoni, Prof, Puzanov, Igor, MD, Dummer, Reinhard, Prof, Schadendorf, Dirk, Prof, Hamid, Omid, MD, Robert, Caroline, Prof, Hodi, F Stephen, MD, Schachter, Jacob, Prof, Pavlick, Anna C, MD, Lewis, Karl D, MD, Cranmer, Lee D, MD, Blank, Christian U, MD, O'Day, Steven J, MD, Ascierto, Paolo A, Prof, Salama, April K S, MD, Margolin, Kim A, Prof, Loquai, Carmen, MD, Eigentler, Thomas K, MD, Gangadhar, Tara C, MD, Carlino, Matteo S, MBBS, Agarwala, Sanjiv S, Prof, Moschos, Stergios J, MD, Sosman, Jeffrey A, Prof, Goldinger, Simone M, MD, Shapira-Frommer, Ronnie, MD, Gonzalez, Rene, Prof, Kirkwood, John M, Prof, Wolchok, Jedd D, Prof, Eggermont, Alexander, Prof, Li, Xiaoyun Nicole, PhD, Zhou, Wei, PhD, Zernhelt, Adriane M, BS, Lis, Joy, BSN, Ebbinghaus, Scot, MD, Kang, S Peter, MD, Daud, Adil, Prof

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Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial von Robert, Caroline, Prof, Ribas, Antoni, Prof, Wolchok, Jedd D, Prof, Hodi, F Stephen, MD, Hamid, Omid, MD, Kefford, Richard, Prof, Weber, Jeffrey S, Prof, Joshua, Anthony M, PhD, Hwu, Wen-Jen, Prof, Gangadhar, Tara C, MD, Patnaik, Amita, MD, Dronca, Roxana, MD, Zarour, Hassane, Prof, Joseph, Richard W, MD, Boasberg, Peter, MD, Chmielowski, Bartosz, MD, Mateus, Christine, MD, Postow, Michael A, MD, Gergich, Kevin, MA, Elassaiss-Schaap, Jeroen, PhD, Li, Xiaoyun Nicole, PhD, Iannone, Robert, MD, Ebbinghaus, Scot W, MD, Kang, S Peter, MD, Daud, Adil, Prof

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Increased brain-predicted aging in treated HIV disease von Cole, James H, Underwood, Jonathan, Caan, Matthan W.A, De Francesco, Davide, van Zoest, Rosan A, Leech, Robert, Wit, Ferdinand W.N.M, Portegies, Peter, Geurtsen, Gert J, Schmand, Ben A, Schim van der Loeff, Maarten F, Franceschi, Claudio, Sabin, Caroline A, Majoie, Charles B.L.M, Winston, Alan, Reiss, Peter, Sharp, David J

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Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course von den Dekker, Herman T, Burrows, Kimberley, Felix, Janine F, Salas, Lucas A, Nedeljkovic, Ivana, Yao, Jin, Rifas-Shiman, Sheryl L, Ruiz-Arenas, Carlos, Amin, N, Bustamante, Mariona, DeMeo, Dawn L, Henderson, A John, Howe, Caitlin G, Hivert, Marie-France, Ikram, M Arfan, de Jongste, Johan C, Lahousse, Lies, Mandaviya, Pooja R, van Meurs, Joyce B, Pinart, Mariona, Sharp, Gemma C, Stolk, Lisette, Uitterlinden, André G, Anto, Josep M, Litonjua, Augusto A, Breton, Carrie V, Brusselle, Guy G, Sunyer, Jordi, Smith, George Davey, Relton, Caroline L, Jaddoe, Vincent W V, Duijts, Liesbeth

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No Evidence for Accelerated Aging-Related Brain Pathology in Treated Human Immunodeficiency Virus: Longitudinal Neuroimaging Results From the Comorbidity in Relation to AIDS (COBRA... von Cole, James H, Caan, Matthan W A, Underwood, Jonathan, De Francesco, Davide, van Zoest, Rosan A, Wit, Ferdinand W N M, Mutsaerts, Henk J M M, Leech, Rob, Geurtsen, Gert J, Portegies, Peter, Majoie, Charles B L M, Schim van der Loeff, Maarten F, Sabin, Caroline A, Reiss, Peter, Winston, Alan, Sharp, David J

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CIS is a potent checkpoint in NK cell–mediated tumor immunity von Delconte, Rebecca B, Kolesnik, Tatiana B, Dagley, Laura F, Rautela, Jai, Shi, Wei, Putz, Eva M, Stannard, Kimberley, Zhang, Jian-Guo, Teh, Charis, Firth, Matt, Ushiki, Takashi, Andoniou, Christopher E, Degli-Esposti, Mariapia A, Sharp, Phillip P, Sanvitale, Caroline E, Infusini, Giuseppe, Liau, Nicholas P D, Linossi, Edmond M, Burns, Christopher J, Carotta, Sebastian, Gray, Daniel H D, Seillet, Cyril, Hutchinson, Dana S, Belz, Gabrielle T, Webb, Andrew I, Alexander, Warren S, Li, Shawn S, Bullock, Alex N, Babon, Jeffery J, Smyth, Mark J, Nicholson, Sandra E, Huntington, Nicholas D

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Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers von van Zoest, Rosan A, Underwood, Jonathan, De Francesco, Davide, Sabin, Caroline A, Cole, James H, Wit, Ferdinand W, Caan, Matthan W A, Kootstra, Neeltje A, Fuchs, Dietmar, Zetterberg, Henrik, Majoie, Charles B L M, Portegies, Peter, Winston, Alan, Sharp, David J, Gisslén, Magnus, Reiss, Peter

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Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens von Schlabach, Michael R, Lin, Sharon, Collester, Zachary R, Wrocklage, Christopher, Shenker, Sol, Calnan, Conor, Xu, Tianlei, Gannon, Hugh S, Williams, Leila J, Thompson, Frank, Dunbar, Paul R, LaMothe, Robert A, Garrett, Tracy E, Colletti, Nicholas, Hohmann, Anja F, Tubo, Noah J, Bullock, Caroline P, Le Mercier, Isabelle, Sofjan, Katri, Merkin, Jason J, Keegan, Sean, Kryukov, Gregory V, Dugopolski, Caroline, Stegmeier, Frank, Wong, Karrie, Sharp, Fiona A, Cadzow, Louise, Benson, Micah J

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Dimensional personality pathology and disordered eating in young adults: measuring the DSM-5 alternative model using the PID-5 von Gilmartin, Tanya Louise, Gurvich, Caroline, Dipnall, Joanna F, Sharp, Gemma

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Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis von Neumann, Alexander, Walton, Esther, Alemany, Silvia, Cecil, Charlotte, González, Juan Ramon, Jima, Dereje D., Lahti, Jari, Tuominen, Samuli T., Barker, Edward D., Binder, Elisabeth, Caramaschi, Doretta, Carracedo, Ángel, Czamara, Darina, Evandt, Jorunn, Felix, Janine F., Fuemmeler, Bernard F., Gutzkow, Kristine B., Hoyo, Cathrine, Julvez, Jordi, Kajantie, Eero, Laivuori, Hannele, Maguire, Rachel, Maitre, Léa, Murphy, Susan K., Murcia, Mario, Villa, Pia M., Sharp, Gemma, Sunyer, Jordi, Raikkönen, Katri, Bakermans-Kranenburg, Marian, IJzendoorn, Marinus van, Guxens, Mònica, Relton, Caroline L., Tiemeier, Henning

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Guidance for estimating penetrance of monogenic disease-causing variants in population cohorts von Wright, Caroline F., Sharp, Luke N., Jackson, Leigh, Murray, Anna, Ware, James S., MacArthur, Daniel G., Rehm, Heidi L., Patel, Kashyap A., Weedon, Michael N.

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Rare coding variants in ten genes confer substantial risk for schizophrenia von Singh, Tarjinder, Poterba, Timothy, Curtis, David, Akil, Huda, Al Eissa, Mariam, Barchas, Jack D., Bass, Nicholas, Bigdeli, Tim B., Breen, Gerome, Bromet, Evelyn J., Buckley, Peter F., Bunney, William E., Bybjerg-Grauholm, Jonas, Byerley, William F., Chapman, Sinéad B., Chen, Wei J., Churchhouse, Claire, Craddock, Nicholas, DeLisi, Lynn, Dodge, Sheila, Escamilla, Michael A., Eskelinen, Saana, Fanous, Ayman H., Faraone, Stephen V., Fiorentino, Alessia, Francioli, Laurent, Gabriel, Stacey B., Gage, Diane, Gagliano Taliun, Sarah A., Ganna, Andrea, Genovese, Giulio, Grove, Jakob, Hall, Mei-Hua, Heyne, Henrike O., Holi, Matti, Hougaard, David M., Howrigan, Daniel P., Huang, Hailiang, Hwu, Hai-Gwo, Kahn, René S., Kang, Hyun Min, Karczewski, Konrad J., Knowles, James A., Lee, Francis S., Lehrer, Douglas S., Lescai, Francesco, Marder, Stephen R., McCarroll, Steven A., McIntosh, Andrew M., Milani, Lili, Morley, Christopher P., Morris, Derek W., Mortensen, Preben Bo, Nordentoft, Merete, O’Brien, Niamh L., Olivares, Ana Maria, Ongur, Dost, Ouwehand, Willem H., Palmer, Duncan S., Paunio, Tiina, Quested, Digby, Rapaport, Mark H., Rees, Elliott, Rollins, Brandi, Satterstrom, F. Kyle, Schatzberg, Alan, Scolnick, Edward, Scott, Laura J., Sharp, Sally I., Sklar, Pamela, Smoller, Jordan W., Solomonson, Matthew, Stahl, Eli A., Stevens, Christine R., Suvisaari, Jaana, Watts, Nicholas A., Blackwood, Douglas H., Cohen, Bruce M., Corvin, Aiden P., Esko, Tõnu, Freimer, Nelson B., Glatt, Stephen J., Hultman, Christina M., McQuillin, Andrew, Palotie, Aarno, Pato, Carlos N., Pato, Michele T., Pulver, Ann E., St. Clair, David, Tsuang, Ming T., Vawter, Marquis P., Walters, James T., Werge, Thomas M., Ophoff, Roel A., Sullivan, Patrick F., Owen, Michael J., Boehnke, Michael, O’Donovan, Michael C., Neale, Benjamin M., Daly, Mark J.

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Changes in bodyweight after initiating antiretroviral therapy close to HIV-1 seroconversion: an international cohort collaboration von Pantazis, Nikos, Sabin, Caroline A, Van der Valk, Marc, Jarrin, Inma, van Sighem, Ard, Carlander, Christina, Gill, John, Volny Anne, Alain, Spire, Bruno, Tariq, Shema, Burns, Fiona, Porter, Kholoud, Moreno, Santiago, Burns, Fiona, Mussini, Cristina, Kamel, Moustafa, Porter, Kholoud, Tariq, Shema, Touloumi, Giota, Vannappagari, Vani, Anne, Alain Volny, Gill, John, Barger, Diana, Fitzgerald, Eli, Karakosta, Argyro, Krentz, Hartmut, Nicholls, Emily Jay, Policek, Nicoletta, Ruiz-Burga, Elisa, Spire, Bruno, Suárez-García, Inés, Andriantsoanirina, Valerie, Avettand-Fenoel, Veronique, Bourgeois, Christine, Chaix, Marie-Laure, Cheret, Antoine, Fischer, Hugues, Goujard, Cecile, Lascoux-Combe, Caroline, Le Palec, Annie, Saez-Cirion, Asier, Seng, Remonie, Stefic, Karl, Piet, E, Gagneux-Brunon, A, Lamaury, I, Bazus, H, Robineau, O, Calin, R, Katlama, J, Denis, B, Ghosn, J, Joly, V, Khuong, M A, Rouveix Nordon, E, de Truchis, P, Abgrall, S, Becker, A, Miailhes, P, Abel, S, Unal, G, Makinson, A, Martin-Blondel, G, Morisot, A, Enel, P, Allavena, C, Rabier, V, Vallet, L, Marchand, L, Saïdi, T, Costagliola, D, Grabar, S, Andriantsoanirina, V, Tattevin, Pierre, Fischer, Hughes, Dalmau, David, Navarro, M Luisa, González, M Isabel, Poveda, Eva, Gutiérrez, Félix, Rubio, Rafael, Berenguer, Juan, Muñoz-Fernández, M Ángeles, Adamis, G, Chini, M, Katsarou, O, Metallidis, S, Panagopoulos, P, Psychogiou, M, Sambatakou, H, Fox, Julie, Terry, Louise, Waters, Anele, Uriel, Alison, Fidler, Sarah, Waters, Laura, Fernandez, Thomas, Nugent, Diarmuid, Fong, Tracy, Pangan, Jaydee

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Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma von Robert, Caroline, Hwu, Wen-Jen, Hamid, Omid, Ribas, Antoni, Weber, Jeffrey S., Daud, Adil I., Hodi, F. Stephen, Wolchok, Jedd D., Mitchell, Tara C., Hersey, Peter, Dronca, Roxana, Joseph, Richard W., Boutros, Celine, Min, Le, Long, Georgina V., Schachter, Jacob, Puzanov, Igor, Dummer, Reinhard, Lin, Jianxin, Ibrahim, Nageatte, Diede, Scott J., Carlino, Matteo S., Joshua, Anthony M.

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One size does not fit all: Exploring how the five‐factor model facets predict disordered eating behaviours among adolescent and young adult males and females von Gilmartin, Tanya, Gurvich, Caroline, Dipnall, Joanna F., Sharp, Gemma

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