Computational Design of Epitope-Specific Functional Antibodies von Nimrod, Guy, Fischman, Sharon, Austin, Mark, Herman, Asael, Keyes, Feenagh, Leiderman, Olga, Hargreaves, David, Strajbl, Marek, Breed, Jason, Klompus, Shelley, Minton, Kevin, Spooner, Jennifer, Buchanan, Andrew, Vaughan, Tristan J., Ofran, Yanay

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Computational design of antibodies von Fischman, Sharon, Ofran, Yanay

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Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling von Petrey, Donald, Xiang, Zhexin, Tang, Christopher L., Xie, Lei, Gimpelev, Marina, Mitros, Therese, Soto, Cinque S., Goldsmith-Fischman, Sharon, Kernytsky, Andrew, Schlessinger, Avner, Koh, Ingrid Y.Y., Alexov, Emil, Honig, Barry

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Structural genomics: Computational methods for structure analysis von Goldsmith‐Fischman, Sharon, Honig, Barry

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Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening von Kalid, Ori, Mense, Martin, Fischman, Sharon, Shitrit, Alina, Bihler, Hermann, Ben-Zeev, Efrat, Schutz, Nili, Pedemonte, Nicoletta, Thomas, Philip J., Bridges, Robert J., Wetmore, Diana R., Marantz, Yael, Senderowitz, Hanoch

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Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A von Fischman, Sharon, Levin, Itay, Rondeau, Jean-Michel, Štrajbl, Marek, Lehmann, Sylvie, Huber, Thomas, Nimrod, Guy, Cebe, Régis, Omer, Dotan, Kovarik, Jiri, Bernstein, Shmuel, Sasson, Yehezkel, Demishtein, Alik, Shlamkovich, Tomer, Bluvshtein, Olga, Grossman, Noam, Barak-Fuchs, Reut, Zhenin, Michael, Fastman, Yair, Twito, Shir, Vana, Tal, Zur, Nevet, Ofran, Yanay

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704 The computationally designed human antibody, AU-007, mediates human immune activation by endogenous IL-2, while uniquely breaking the IL-2 auto-inhibitory loop and preventing T... von Amit, Inbar, Levin, Itay, Wyant, Timothy, Levitan, Natali, Barak, Reut, Ben-Mayor, May, Bluvshtein, Olga, Grossman, Noam, Sasson, Yehezkel, Nimrod, Guy, Zehnin, Michael, Fischman, Sharon, Štrajbl, Marek, Danielpur, Liron, Knickerbocker, Aron, Vasselli, James, Ofran, Yanay

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Accurate profiling of full-length Fv in highly homologous antibody libraries using UMI tagged short reads von Levin, Itay, Štrajbl, Marek, Fastman, Yair, Baran, Dror, Twito, Shir, Mioduser, Jessica, Keren, Adi, Fischman, Sharon, Zhenin, Michael, Nimrod, Guy, Levitin, Natalie, Mayor, May Ben, Gadrich, Meital, Ofran, Yanay

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NMR structure of the 18 kDa protein CC1736 from Caulobacter crescentus identifies a member of the "START" domain superfamily and suggests residues mediating substrate specificity von Shen, Yang, Goldsmith-Fischman, Sharon, Atreya, Hanudatta S., Acton, Thomas, Ma, LiChung, Xiao, Rong, Honig, Barry, Montelione, Gaetano T., Szyperski, Thomas

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Solution structure of Archaeglobus fulgidis peptidyl‐tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes von Powers, Robert, Mirkovic, Nebojsa, Goldsmith‐Fischman, Sharon, Acton, Thomas B., Chiang, Yiwen, Huang, Yuanpeng J., Ma, Lichung, Rajan, P.K., Cort, John R., Kennedy, Michael A., Liu, Jinfeng, Rost, Burkhard, Honig, Barry, Murray, Diana, Montelione, Gaetano T.

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Characterization of BDG8: An antibody-human IL-2 complex that selectively activates the effector arm of the immune system von Wyant, Timothy, Amit, Inbar, Levin, Itay, Levitan, Natali, Grossman, Noam, Bluvshtein, Olga, Barak, Ruet, Nimrod, Guy, Fischman, Sharon, Strajbl, Marek, Sasson, Yehezkel, Zehnin, Michael, Ofran, Yanay

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The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis von Thibodeau, Patrick H., Richardson, John M., Wang, Wei, Millen, Linda, Watson, Jarod, Mendoza, Juan L., Du, Kai, Fischman, Sharon, Senderowitz, Hanoch, Lukacs, Gergely L., Kirk, Kevin, Thomas, Philip J.

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NMR structure of the hypothetical protein NMA1147 from Neisseria meningitidis Reveals a distinct 5-helix bundle von Liu, Gaohua, Sukumaran, Dinesh K., Xu, Duanxiang, Chiang, Yiwen, Acton, Thomas, Goldsmith-Fischman, Sharon, Honig, Barry, Montelione, Gaetano T., Szyperski, Thomas

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NMR structure of the hypothetical protein AQ-1857 encoded by the Y157 gene from Aquifex aeolicus reveals a novel protein fold von Xu, Duanxiang, Liu, Gaohua, Xiao, Rong, Acton, Tom, Goldsmith-Fischman, Sharon, Honig, Barry, Montelione, Gaetano T., Szyperski, Thomas

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Crystal structures of MTH1187 and its yeast ortholog YBL001c von Tao, Xiao, Khayat, Reza, Christendat, Dinesh, Savchenko, Alexei, Xu, Xiaohui, Goldsmith-Fischman, Sharon, Honig, Barry, Edwards, Aled, Arrowsmith, Cheryl H., Tong, Liang

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Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii von Aramini, James M., Huang, Yuanpeng J., Cort, John R., Goldsmith‐Fischman, Sharon, Xiao, Rong, Shih, Liang‐Yu, Ho, Chi K., Liu, Jinfeng, Rost, Burkhard, Honig, Barry, Kennedy, Michael A., Acton, Thomas B., Montelione, Gaetano T.

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Solution structure of Vibrio cholerae protein VC0424: A variation of the ferredoxin‐like fold von Ramelot, Theresa A., Ni, Shuisong, Goldsmith‐Fischman, Sharon, Cort, John R., Honig, Barry, Kennedy, Michael A.

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Solution NMR Structure of the Iron–Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site von Ramelot, Theresa A., Cort, John R., Goldsmith-Fischman, Sharon, Kornhaber, Gregory J., Xiao, Rong, Shastry, Ritu, Acton, Thomas B., Honig, Barry, Montelione, Gaetano T., Kennedy, Michael A.

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The SufE Sulfur-acceptor Protein Contains a Conserved Core Structure that Mediates Interdomain Interactions in a Variety of Redox Protein Complexes von Goldsmith-Fischman, Sharon, Kuzin, Alexandre, Edstrom, William C., Benach, Jordi, Shastry, Ritu, Xiao, Rong, Acton, Thomas B., Honig, Barry, Montelione, Gaetano T., Hunt, John F.

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COMPUTER ASSISTED ANTIBODY RE-EPITOPING von OFRAN, Yanay, NIMROD, Guy, FISCHMAN, Sharon, HERMAN, Asael

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