Drugging Undruggable Molecular Cancer Targets von Lazo, John S, Sharlow, Elizabeth R

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Emerging drug discovery ecosystems von Sharlow, Elizabeth R

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Pharmacological profiling identifies divergent chemosensitivities of differentiating and maturing iPSC-derived human cortical neuron populations von Sharlow, Elizabeth R, Llaneza, Danielle C, Tewari, Bhanu P, Mingledorff, Garnett A, Mendelson, Anna J, Sontheimer, Harald, Bloom, George S, Lazo, John S

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The SARS-CoV-2 spike protein subunit S1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells von Colunga Biancatelli, Ruben M L, Solopov, Pavel A, Sharlow, Elizabeth R, Lazo, John S, Marik, Paul E, Catravas, John D

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Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor von Salamoun, Joseph M, McQueeney, Kelley E, Patil, Kalyani, Geib, Steven J, Sharlow, Elizabeth R, Lazo, John S, Wipf, Peter

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Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase von Lazo, John S, Blanco, Isabella K, Tasker, Nikhil R, Rastelli, Ettore J, Burnett, James C, Garrott, Sharon R, Hart, Duncan J, McCloud, Rebecca L, Hsu, Ku-Lung, Wipf, Peter, Sharlow, Elizabeth R

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Potent and Selective Disruption of Protein Kinase D Functionality by a Benzoxoloazepinolone von Sharlow, Elizabeth R., Giridhar, Karthik V., LaValle, Courtney R., Chen, Jun, Leimgruber, Stephanie, Barrett, Rebecca, Bravo-Altamirano, Karla, Wipf, Peter, Lazo, John S., Wang, Q. Jane

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Introduction to the iPS Cells for Ischemic Stroke, Traumatic Brain Injury, and Other Brain-Related Diseases Special Issue von Sharlow, Elizabeth R.

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High content screening miniaturization and single cell imaging of mature human feeder layer-free iPSC-derived neurons von Sharlow, Elizabeth R., Llaneza, Danielle C., Grever, William E., Mingledorff, Garnett A., Mendelson, Anna J., Bloom, George S., Lazo, John S.

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Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer von Lazo, John S., Sharlow, Elizabeth R., Cornelison, Robert, Hart, Duncan J., Llaneza, Danielle C., Mendelson, Anna J., Rastelli, Ettore J., Tasker, Nikhil R., Landen, Charles N., Wipf, Peter

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Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death von Lazo, John S, Sharlow, Elizabeth R, Epperly, Michael W, Lira, Ana, Leimgruber, Stephanie, Skoda, Erin M, Wipf, Peter, Greenberger, Joel S

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Identifying Actives from HTS Data Sets: Practical Approaches for the Selection of an Appropriate HTS Data-Processing Method and Quality Control Review von Shun, Tong Ying, Lazo, John S., Sharlow, Elizabeth R., Johnston, Paul A.

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Revisiting Repurposing von Sharlow, Elizabeth R

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Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen von Sharlow, Elizabeth R, Close, David, Shun, Tongying, Leimgruber, Stephanie, Reed, Robyn, Mustata, Gabriela, Wipf, Peter, Johnson, Jacob, O'Neil, Michael, Grögl, Max, Magill, Alan J, Lazo, John S

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A Phase I Pharmacokinetic and Pharmacodynamic Study of PX-12, a Novel Inhibitor of Thioredoxin-1, in Patients with Advanced Solid Tumors von RAMANATHAN, Ramesh K, KIRKPATRICK, D. Lynn, DRAGOVICH, Tomislav, BELANI, Chandra P, FRIEDLAND, David, GREEN, Sylvan B, CHOW, H-H. Sherry, CORDOVA, Catherine A, STRATTON, Steven P, SHARLOW, Elizabeth R, BAKER, Amanda

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Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity von Sharlow, Elizabeth R, Mustata Wilson, Gabriela, Close, David, Leimgruber, Stephanie, Tandon, Manuj, Reed, Robyn B, Shun, Tong Ying, Wang, Q Jane, Wipf, Peter, Lazo, John S

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A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity von Sharlow, Elizabeth R, Lyda, Todd A, Dodson, Heidi C, Mustata, Gabriela, Morris, Meredith T, Leimgruber, Stephanie S, Lee, Kuo-Hsiung, Kashiwada, Yoshiki, Close, David, Lazo, John S, Morris, James C

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Small molecule targeting of PTPs in cancer von Lazo, John S., McQueeney, Kelley E., Burnett, James C., Wipf, Peter, Sharlow, Elizabeth R.

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Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase von Lazo, John S., Isbell, Kelly N., Rastelli, Ettore J., Wipf, Peter, Sharlow, Elizabeth R.

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Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase von Lazo, John S, Isbell, Kelly N, Vasa, Sai Ashish, Llaneza, Danielle C, Rastelli, Ettore J, Wipf, Peter, Sharlow, Elizabeth R

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