PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells von Sheshadri, Namratha, Poria, Dipak K., Sharan, Shikha, Hu, Ying, Yan, Chunhua, Koparde, Vishal N., Balamurugan, Kuppusamy, Sterneck, Esta

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Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBPδ Expression and Contributes to Transformation of Breast Tumor Cells von Sarkar, Tapasree Roy, Sharan, Shikha, Wang, Jun, Pawar, Snehalata A., Cantwell, Carrie A., Johnson, Peter F., Morrison, Deborah K., Wang, Ju-Ming, Sterneck, Esta

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C/EBPδ targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression von Pawar, Snehalata A, Sarkar, Tapasree Roy, Balamurugan, Kuppusamy, Sharan, Shikha, Wang, Jun, Zhang, Youhong, Dowdy, Steven F, Huang, A. Mei, Sterneck, Esta

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Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer von Balamurugan, Kuppusamy, Poria, Dipak K, Sehareen, Saadiya W, Krishnamurthy, Savitri, Tang, Wei, McKennett, Lois, Padmanaban, Veena, Czarra, Kelli, Ewald, Andrew J, Ueno, Naoto T, Ambs, Stefan, Sharan, Shikha, Sterneck, Esta

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CCAAT/enhancer binding protein delta (C/EBPδ, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage von Wang, Jun, Sarkar, Tapasree Roy, Zhou, Ming, Sharan, Shikha, Ritt, Daniel A, Veenstra, Timothy D, Morrison, Deborah K, Huang, A. Mei, Sterneck, Esta

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The STAT3 inhibitor Stattic acts independently of STAT3 to decrease histone acetylation and modulate gene expression von Poria, Dipak K., Sheshadri, Namratha, Balamurugan, Kuppusamy, Sharan, Shikha, Sterneck, Esta

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Abstract 2031: The PERK arm of the unfolded protein response induces CXCL8 and CCL20 through C/EBPδ von Poria, Dipak Kumar, Sheshadri, Namratha, Sharan, Shikha, Sterneck, Esta

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Loss of CCAAT/enhancer binding protein δ promotes chromosomal instability von Huang, A-Mei, Montagna, Cristina, Sharan, Shikha, Ni, Yajun, Ried, Thomas, Sterneck, Esta

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Abstract 4501: CEBPD is an early endoplasmic reticulum stress response gene implicated in breast cancer cell survival von Sheshadri, Namratha, Sharan, Shikha, Sterneck, Esta

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CEBPD is an early endoplasmic reticulum stress response gene implicated in breast cancer cell survival von Sheshadri, Namratha, Sharan, Shikha, Sterneck, Esta

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C/EBPδ links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes von Balamurugan, Kuppusamy, Mendoza-Villanueva, Daniel, Sharan, Shikha, Summers, Glenn H., Dobrolecki, Lacey E., Lewis, Michael T., Sterneck, Esta

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The Cebpd (C/EBPdelta) gene is induced by luteinizing hormones in ovarian theca and interstitial cells but is not essential for mouse ovary function von Huang, A-Mei, Rudelius, Martina, Sharan, Shikha, McAllister, Jan M, Raffeld, Mark, Christenson, Lane K, Sterneck, Esta

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Abstract P1-06-03: Promotion of E-cadherin-mediated tumor cell adhesion by COX-2/GSK3β signaling is a targetable mechanism of metastatic breast cancer von Balamurugan, Kuppusamy, Sehareen, Saadiya, Krishnamurthy, Savitri, Sharan, Shikha, Tang, Wei, Ueno, Naoto, Ambs, Stefan, Poria, Dipak, Sterneck, Esta

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The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis von Balamurugan, Kuppusamy, Wang, Ju-Ming, Tsai, Hsin-Hwa, Sharan, Shikha, Anver, Miriam, Leighty, Robert, Sterneck, Esta

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C/EBP[delta] links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes von Balamurugan, Kuppusamy, Mendoza-Villanueva, Daniel, Sharan, Shikha, Summers, Glenn H, Dobrolecki, Lacey E, Lewis, Michael T, Sterneck, Esta

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FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4 von Balamurugan, Kuppusamy, Sharan, Shikha, Klarmann, Kimberly D., Zhang, Youhong, Coppola, Vincenzo, Summers, Glenn H., Roger, Thierry, Morrison, Deborah K., Keller, Jonathan R., Sterneck, Esta

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Comparison of mammary gland involution between 129S1 and C57BL 6 inbred mouse strains: differential regulation of Bcl2a1, Trp53, Cebpb, and Cebpd expression von Thangaraju, Muthusamy, Sharan, Shikha, Sterneck, Esta

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Abstract 1913: C/EBPdelta links hypoxia and inflammation to the promotion of tumor cell stemness through inhibition of FBXW7: A molecular target for HDAC inhibitor action von Balamurugan, Kuppusamy, Summers, Glenn H., Sharan, Shikha, Sterneck, Esta

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The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression and associates with good prognosis in breast cancer von Mendoza-Villanueva, D, Balamurugan, K, Ali, H R, Kim, S-R, Sharan, S, Johnson, R C, Merchant, A S, Caldas, C, Landberg, G, Sterneck, E

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Abstract 2017: The CEBPD transcription factor, a marker of good prognosis in breast cancer, becomes a signaling hub for promotion of cancer cell stemness by hypoxia and interleukin... von Balamurugan, Kuppusamy, Mendoza-Villanueva, Daniel, Rath, Barbara, Tofilon, Philip, Sharan, Shikha, Sterneck, Esta

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