Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment von Zhao, Yujun, Aguilar, Angelo, Bernard, Denzil, Wang, Shaomeng

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Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy von Shangary, Sanjeev, Wang, Shaomeng

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Targeting Apoptosis Pathways for New Cancer Therapeutics von Bai, Longchuan, Wang, Shaomeng

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Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein von Wang, Mingliang, Lu, Jianfeng, Wang, Mi, Yang, Chao-Yie, Wang, Shaomeng

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Targeting the MDM2-p53 Interaction for Cancer Therapy von SHANGARY, Sanjeev, WANG, Shaomeng

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Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer von Han, Xin, Wang, Chao, Qin, Chong, Xiang, Weiguo, Fernandez-Salas, Ester, Yang, Chao-Yie, Wang, Mi, Zhao, Lijie, Xu, Tianfeng, Chinnaswamy, Krishnapriya, Delproposto, James, Stuckey, Jeanne, Wang, Shaomeng

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Therapeutic Strategies to Activate p53 von Aguilar, Angelo, Wang, Shaomeng

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A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo von Zhao, Lijie, Han, Xin, Lu, Jianfeng, McEachern, Donna, Wang, Shaomeng

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Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumo... von Li, Yangbing, Yang, Jiuling, Aguilar, Angelo, McEachern, Donna, Przybranowski, Sally, Liu, Liu, Yang, Chao-Yie, Wang, Mi, Han, Xin, Wang, Shaomeng

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Elucidation of Resistance Mechanisms to Second-Generation ALK Inhibitors Alectinib and Ceritinib in Non–Small Cell Lung Cancer Cells von Dong, Xuyuan, Fernandez-Salas, Ester, Li, Enxiao, Wang, Shaomeng

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Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer von Asangani, Irfan A., Dommeti, Vijaya L., Wang, Xiaoju, Malik, Rohit, Cieslik, Marcin, Yang, Rendong, Escara-Wilke, June, Wilder-Romans, Kari, Dhanireddy, Sudheer, Engelke, Carl, Iyer, Mathew K., Jing, Xiaojun, Wu, Yi-Mi, Cao, Xuhong, Qin, Zhaohui S., Wang, Shaomeng, Feng, Felix Y., Chinnaiyan, Arul M.

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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Induc... von Qin, Chong, Hu, Yang, Zhou, Bing, Fernandez-Salas, Ester, Yang, Chao-Yie, Liu, Liu, McEachern, Donna, Przybranowski, Sally, Wang, Mi, Stuckey, Jeanne, Meagher, Jennifer, Bai, Longchuan, Chen, Zhuo, Lin, Mei, Yang, Jiuling, Ziazadeh, Danya N, Xu, Fuming, Hu, Jiantao, Xiang, Weiguo, Huang, Liyue, Li, Siwei, Wen, Bo, Sun, Duxin, Wang, Shaomeng

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Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein von Zhou, Haibin, Bai, Longchuan, Xu, Renqi, Zhao, Yujun, Chen, Jianyong, McEachern, Donna, Chinnaswamy, Krishnapriya, Wen, Bo, Dai, Lipeng, Kumar, Praveen, Yang, Chao-Yie, Liu, Zhaomin, Wang, Mi, Liu, Liu, Meagher, Jennifer L, Yi, Han, Sun, Duxin, Stuckey, Jeanne A, Wang, Shaomeng

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On-Wafer Microstrip Meander-Line Slow-Wave Structure at Ka-Band von Wang, Shaomeng, Aditya, Sheel, Xia, Xin, Ali, Zishan, Miao, Jianmin

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Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment von Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.

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The Making of I‑BET762, a BET Bromodomain Inhibitor Now in Clinical Development von Zhao, Yujun, Yang, Chao-Yie, Wang, Shaomeng

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Complex Permittivity Characterization of Liquid Samples Based on a Split Ring Resonator (SRR) von Ma, Jialu, Tang, Jingchao, Wang, Kaicheng, Guo, Lianghao, Gong, Yubin, Wang, Shaomeng

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A Potent Small-Molecule Inhibitor of the MDM2–p53 Interaction (MI-888) Achieved Complete and Durable Tumor Regression in Mice von Zhao, Yujun, Yu, Shanghai, Sun, Wei, Liu, Liu, Lu, Jianfeng, McEachern, Donna, Shargary, Sanjeev, Bernard, Denzil, Li, Xiaoqin, Zhao, Ting, Zou, Peng, Sun, Duxin, Wang, Shaomeng

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Resistance to BET Inhibitor Leads to Alternative Therapeutic Vulnerabilities in Castration-Resistant Prostate Cancer von Pawar, Aishwarya, Gollavilli, Paradesi Naidu, Wang, Shaomeng, Asangani, Irfan A.

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The Ecstasy and Agony of Assay Interference Compounds von Aldrich, Courtney, Bertozzi, Carolyn, Georg, Gunda I, Kiessling, Laura, Lindsley, Craig, Liotta, Dennis, Merz, Jr, Kenneth M, Schepartz, Alanna, Wang, Shaomeng

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