Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction von Jiang, Changtao, Xie, Cen, Lv, Ying, Li, Jing, Krausz, Kristopher W., Shi, Jingmin, Brocker, Chad N., Desai, Dhimant, Amin, Shantu G., Bisson, William H., Liu, Yulan, Gavrilova, Oksana, Patterson, Andrew D., Gonzalez, Frank J.

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Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity von Dong, Fangcong, Hao, Fuhua, Murray, Iain A., Smith, Philip B., Koo, Imhoi, Tindall, Alyssa M., Kris-Etherton, Penny M., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

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Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors von Plano, Daniel, Amin, Shantu, Sharma, Arun K

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Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides von Singh, Amandeep, Raza, Asif, Amin, Shantu, Damodaran, Chendil, Sharma, Arun K

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Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming von Zhou, Xiaoliang, Chakraborty, Debopriya, Murray, Iain A., Coslo, Denise, Kehs, Zoe, Vijay, Anitha, Ton, Carolyn, Desai, Dhimant, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

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Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis von Young, Megan M., Takahashi, Yoshinori, Khan, Osman, Park, Sungman, Hori, Tsukasa, Yun, Jong, Sharma, Arun K., Amin, Shantu, Hu, Chang-Deng, Zhang, Jianke, Kester, Mark, Wang, Hong-Gang

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D1 dopamine receptors intrinsic activity and functional selectivity affect working memory in prefrontal cortex von Yang, Yang, Lee, Sang-Min, Imamura, Fumiaki, Gowda, Krishne, Amin, Shantu, Mailman, Richard B.

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Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia von Song, Chunhua, Gowda, Chandrika, Pan, Xiaokang, Ding, Yali, Tong, Yongqing, Tan, Bi-Hua, Wang, Haijun, Muthusami, Sunil, Ge, Zheng, Sachdev, Mansi, Amin, Shantu G., Desai, Dhimant, Gowda, Krishne, Gowda, Raghavendra, Robertson, Gavin P., Schjerven, Hilde, Muschen, Markus, Payne, Kimberly J., Dovat, Sinisa

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KS18, a Mcl-1 inhibitor, improves the effectiveness of bortezomib and overcomes resistance in refractory multiple myeloma by triggering intrinsic apoptosis von Al-Odat, Omar S, Elbezanti, Weam Othman, Gowda, Krishne, Srivastava, Sandeep K, Amin, Shantu G, Jonnalagadda, Subash C, Budak-Alpdogan, Tulin, Pandey, Manoj K

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Ah receptor antagonism represses head and neck tumor cell aggressive phenotype von DiNatale, Brett C, Smith, Kayla, John, Kaarthik, Krishnegowda, Gowdahalli, Amin, Shantu G, Perdew, Gary H

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Pharmacological agents targeting drug-tolerant persister cells in cancer von Chen, Yu-Chi, Gowda, Krishne, Amin, Shantu, Schell, Todd D., Sharma, Arun K., Robertson, Gavin P.

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Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor von Gowda, Krishne, Raza, Asif, Vangala, Venugopal, Lone, Nazir Ahmad, Lin, Jyh Ming, Singh, Jaikee Kumar, Srivastava, Sandeep Kumar, Schell, Todd D, Robertson, Gavin P, Amin, Shantu, Sharma, Arun K

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Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity von Muku, Gulsum E., Kusnadi, Ann, Kuzu, Guray, Tanos, Rachel, Murray, Iain A., Gowda, Krishne, Amin, Shantu, Perdew, Gary H.

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Selenium-Based Novel Epigenetic Regulators Offer Effective Chemotherapeutic Alternative with Wider Safety Margins in Experimental Colorectal Cancer von Ghanghas, Preety, Sharma, Monika, Desai, Dhimant, Raza, Kaisar, Bhalla, Aman, Kumar, Pramod, Narula, Dipika, Amin, Shantu, Sanyal, Sankar Nath, Kaushal, Naveen

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Crucial role of macrophage selenoproteins in experimental colitis von Kaushal, Naveen, Kudva, Avinash K, Patterson, Andrew D, Chiaro, Christopher, Kennett, Mary J, Desai, Dhimant, Amin, Shantu, Carlson, Bradley A, Cantorna, Margherita T, Prabhu, K Sandeep

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Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5 von Cruz, Linda, Streck, Nicholas T, Ferguson, Kevin, Desai, Trisha, Desai, Dhimant H, Amin, Shantu G, Buchkovich, Nicholas J

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Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways von Pandey, Manoj K, Kale, Vijay P, Song, Chunhua, Sung, Shen-shu, Sharma, Arun K, Talamo, Giampaolo, Dovat, Sinisa, Amin, Shantu G

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Lead optimization of aryl hydrocarbon receptor ligands for treatment of inflammatory skin disorders von Rikken, Gijs, Smith, Kayla J., van den Brink, Noa J.M., Smits, Jos P.H., Gowda, Krishne, Alnemri, Angela, Kuzu, Gulsum E., Murray, Iain A., Lin, Jyh-Ming, Smits, Jos G.A., van Vlijmen-Willems, Ivonne M., Amin, Shantu G., Perdew, Gary H., van den Bogaard, Ellen H.

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Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer von Morad, Samy A.F., Davis, Traci S., MacDougall, Matthew R., Tan, Su-Fern, Feith, David J., Desai, Dhimant H., Amin, Shantu G., Kester, Mark, Loughran, Thomas P., Cabot, Myles C.

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Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice von Jiang, Jie, Ma, Yuandi, Liu, Yameng, Lu, Dasheng, Gao, Xiaoxia, Krausz, Kristopher W., Desai, Dhimant, Amin, Shantu G., Patterson, Andrew D., Gonzalez, Frank J., Xie, Cen

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