Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future von UNEMO, Magnus, SHAFER, William M

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Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future von Unemo, Magnus, Shafer, William M.

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Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution von Golparian, Daniel, Harris, Simon R., Sanchez-Buso, Leonor, Hoffmann, Steen, Shafer, William M., Bentley, Stephen D., Jensen, Jorgen S., Unemo, Magnus

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Importance of Multidrug Efflux Pumps in the Antimicrobial Resistance Property of Clinical Multidrug-Resistant Isolates of Neisseria gonorrhoeae von GOLPARIAN, Daniel, SHAFER, William M, OHNISHI, Makoto, UNEMO, Magnus

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Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines von Alirol, Emilie, Wi, Teodora E, Bala, Manju, Bazzo, Maria Luiza, Chen, Xiang-Sheng, Deal, Carolyn, Dillon, Jo-Anne R, Kularatne, Ranmini, Heim, Jutta, Hooft van Huijsduijnen, Rob, Hook, Edward W, Lahra, Monica M, Lewis, David A, Ndowa, Francis, Shafer, William M, Tayler, Liz, Workowski, Kimberly, Unemo, Magnus, Balasegaram, Manica

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The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae von Leduc, Isabelle, Connolly, Kristie L., Begum, Afrin, Underwood, Knashka, Darnell, Stephen, Shafer, William M., Balthazar, Jacqueline T., Macintyre, Andrew N., Sempowski, Gregory D., Duncan, Joseph A., Little, Marguerite B., Rahman, Nazia, Garges, Eric C., Jerse, Ann E.

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Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation von Ayala, Julio C, Balthazar, Jacqueline T, Shafer, William M

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Transcriptional regulation of a gonococcal gene encoding a virulence factor (L-lactate permease) von Ayala, Julio C, Shafer, William M

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Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance von Lyu, Meinan, Moseng, Mitchell A., Reimche, Jennifer L., Holley, Concerta L., Dhulipala, Vijaya, Su, Chih-Chia, Shafer, William M., Yu, Edward W.

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Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations von Beggs, Grace A, Ayala, Julio C, Kavanaugh, Logan G, Read, Timothy D, Hooks, Grace M, Schumacher, Maria A, Shafer, William M, Brennan, Richard G

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Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR von Holley, Concerta L, Dhulipala, Vijaya, Maurakis, Stavaros A, Greenawalt, Ashley Nicole, Read, Timothy D, Cornelissen, Cynthia N, Shafer, William M

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Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR von Hooks, Grace M., Ayala, Julio C., Holley, Concerta L., Dhulipala, Vijaya, Beggs, Grace A., Perfect, John R., Schumacher, Maria A., Shafer, William M., Brennan, Richard G.

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A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch von Sanchez-Buso, Leonor, Yeats, Corin A., Taylor, Benjamin, Goater, Richard J., Underwood, Anthony, Abudahab, Khalil, Argimon, Silvia, Ma, Kevin C., Mortimer, Tatum D., Golparian, Daniel, Cole, Michelle J., Grad, Yonatan H., Martin, Irene, Raphael, Brian H., Shafer, William M., Town, Katy, Wi, Teodora, Harris, Simon R., Unemo, Magnus, Aanensen, David M.

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Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump von Bolla, Jani Reddy, Su, Chih-Chia, Do, Sylvia V, Radhakrishnan, Abhijith, Kumar, Nitin, Long, Feng, Chou, Tsung-Han, Delmar, Jared A, Lei, Hsiang-Ting, Rajashankar, Kanagalaghatta R, Shafer, William M, Yu, Edward W

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Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages von Zughaier, Susu M, Kandler, Justin L, Shafer, William M

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Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter M... von Ayala, Julio C, Schmerer, Matthew W, Kersh, Ellen N, Unemo, Magnus, Shafer, William M

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Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel von Lei, Hsiang-Ting, Chou, Tsung-Han, Su, Chih-Chia, Bolla, Jani Reddy, Kumar, Nitin, Radhakrishnan, Abhijith, Long, Feng, Delmar, Jared A, Do, Sylvia V, Rajashankar, Kanagalaghatta R, Shafer, William M, Yu, Edward W

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Polyamines Can Increase Resistance of Neisseria gonorrhoeae to Mediators of the Innate Human Host Defense von Goytia, Maira, Shafer, William M

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Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development von Rice, Peter A, Shafer, William M, Ram, Sanjay, Jerse, Ann E

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Drug Targeting a Gonococcal Virulence Factor Exploits Host Antimicrobial Peptides in Clearance of Infection von Shafer, William M

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