Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus von Green, N K, Herbert, C W, Hale, S J, Hale, A B, Mautner, V, Harkins, R, Hermiston, T, Ulbrich, K, Fisher, K D, Seymour, L W

Volltext

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery von DASH, P. R, READ, M. L, BARRETT, L. B, WOLFERT, M. A, SEYMOUR, L. W

Volltext

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies von FISHER, K. D, STALLWOOD, Y, GREEN, N. K, ULBRICH, K, MAUTNER, V, SEYMOUR, L. W

Volltext

Laterally Stabilized Complexes of DNA with Linear Reducible Polycations:  Strategy for Triggered Intracellular Activation of DNA Delivery Vectors von Oupický, David, Parker, Alan L, Seymour, Leonard W

Volltext

Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin von Mulholland, P. J., Ferry, D. R., Anderson, D., Hussain, S. A., Young, A. M., Cook, J. E., Hodgkin, E., Seymour, L. W., Kerr, D. J.

Volltext

Factors influencing retention of adenovirus within tumours following direct intratumoural injection von Bazan-Peregrino, M, Carlisle, R C, Purdie, L, Seymour, L W

Volltext

DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers von Oupický, D., Koňák, Č., Ulbrich, K., Wolfert, M.A., Seymour, L.W.

Volltext

Nanotherapeutics Shielded With a pH Responsive Polymeric Layer von KOSTKA, L., ŠUBR, V., LAGA, R., CHYTIL, P., ULBRICH, K., SEYMOUR, L. W., ETRYCH, T.

Volltext

Comparison of Molecular Strategies for Breast Cancer Virotherapy Using Oncolytic Adenovirus von BAZAN-PEREGRINO, M, CARLISLE, R. C, HERNANDEZ-ALCOCEBA, R, IGGO, R, HOMICSKO, K, FISHER, K. D, HALLDEN, G, MAUTNER, V, SHEN, Y, SEYMOUR, L. W

Volltext

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo von OUPICKY, D, CARLISLE, R. C, SEVMOUR, L. W

Volltext

Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via α6-integrins von Stevenson, M, Hale, A B H, Hale, S J, Green, N K, Black, G, Fisher, K D, Ulbrich, K, Fabra, A, Seymour, L W

Volltext

A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression von FISHER, K. D, ULBRICH, K, SUBR, V, WARD, C. M, MAUTNER, V, BLAKEY, D, SEYMOUR, L. W

Volltext

Chloroquine and amphipathic peptide helices show synergistic transfection in vitro von WOLFERT, M. A, SEYMOUR, L. W

Volltext

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data von Arriagada, R, Auperin, A, Burdett, S, Higgins, J P, Johnson, D H, Le Chevalier, T, Le Pechoux, C, Parmar, M K B, Pignon, J P, Souhami, R L, Stephens, R J, Stewart, L A, Tierney, J F, Tribodet, H, van Meerbeeck, J

Volltext

Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier von Seymour, L.W., Miyamoto, Y., Maeda, H., Brereton, M., Strohalm, J., Ulbrich, K., Duncan, R.

Volltext

Poly- l-glutamic acid derivatives as vectors for gene therapy von Dekie, Luc, Toncheva, Veska, Dubruel, Peter, Schacht, Etienne H., Barrett, Lee, Seymour, Leonard W.

Volltext

Hepatic Drug Targeting: Phase I Evaluation of Polymer-Bound Doxorubicin von Seymour, L. W.

Volltext

Key issues in non-viral gene delivery von Pouton, Colin W, Seymour, Leonard W

Volltext

Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine von Julyan, Peter J, Seymour, Leonard W, Ferry, David R, Daryani, Sunil, Boivin, Christopher M, Doran, Jayne, David, Marilyn, Anderson, David, Christodoulou, Christos, Young, Annie M, Hesslewood, Stuart, Kerr, David J

Volltext

Combining virotherapy and angiotherapy for the treatment of breast cancer von Bazan-Peregrino, M, Sainson, R C A, Carlisle, R C, Thoma, C, Waters, R A, Arvanitis, C, Harris, A L, Hernandez-Alcoceba, R, Seymour, L W

Volltext