High-Throughput and Multiplexed LC/MS/MRM Method for Targeted Metabolomics von Wei, Ru, Li, Guodong, Seymour, Albert B

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siRNA off-target effects can be reduced at concentrations that match their individual potency von Caffrey, Daniel R, Zhao, Juan, Song, Zhili, Schaffer, Michael E, Haney, Steven A, Subramanian, Romesh R, Seymour, Albert B, Hughes, Jason D

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Relation of Increased Prebeta-1 High-Density Lipoprotein Levels to Risk of Coronary Heart Disease von Guey, Lin T., PhD, Pullinger, Clive R., PhD, Ishida, Brian Y., PhD, O'Connor, Patricia M., MD, Zellner, Christian, MD, Francone, Omar L., PhD, Laramie, Jason M., PhD, Naya-Vigne, Josefina M., MD, Siradze, Ketevan A., MD, Deedwania, Prakash, MD, Redberg, Rita F., MD, Frost, Philip H., MD, Seymour, Albert B., PhD, Kane, John P., MD, PhD, Malloy, Mary J., MD

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Natural variations in AAVHSC16 significantly reduce liver tropism and maintain broad distribution to periphery and CNS von Smith, Laura J., Schulman, Lindsay A., Smith, Samantha, Van Lieshout, Laura, Barnes, Carmen M., Behmoiras, Liana, Scarpitti, Meghan, Kivaa, Monicah, Duong, Khanh L., Benard, Ludo O., Ellsworth, Jeff L., Avila, Nancy, Faulkner, Deiby, Hayes, April, Lotterhand, Jason, Rivas, Jose Israel, Sengooba, Arnold V., Tzianabos, Alec, Seymour, Albert B., Francone, Omar L.

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Single Systemic Administration of a Gene Therapy Leading to Disease Treatment in Metachromatic Leukodystrophy Arsa Knock-Out Mice von St Martin, Thia, Seabrook, Tania A, Gall, Katherine, Newman, Jenn, Avila, Nancy, Hayes, April, Kivaa, Monicah, Lotterhand, Jason, Mercaldi, Michael, Patel, Kruti, Rivas, Israel J, Woodcock, Stephen, Wright, Teresa L, Seymour, Albert B, Francone, Omar L, Gingras, Jacinthe

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Frequent somatic mutations and homozygous deletions of the p16 ( MTS1 ) gene in pancreatic adenocarcinoma von Caldas, Carlos, Hahn, Stephan A, da Costa, Luis T, Redston, Mark S, Schutte, Mieke, Seymour, Albert B, Weinstein, Craig L, Hruban, Ralph H, Yeo, Charles J, Kern, Scott E

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Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels von Mank-Seymour, Amy R., Durham, Kathryn L., Thompson, John F., Seymour, Albert B., Milos, Patrice M.

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Multiplexed, Quantitative, and Targeted Metabolite Profiling by LC-MS/MRM von Wei, Ru, Li, Guodong, Seymour, Albert B.

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Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants von Guey, Lin T., Kravic, Jasmina, Melander, Olle, Burtt, Noël P., Laramie, Jason M., Lyssenko, Valeriya, Jonsson, Anna, Lindholm, Eero, Tuomi, Tiinamaija, Isomaa, Bo, Nilsson, Peter, Almgren, Peter, Kathiresan, Sekar, Groop, Leif, Seymour, Albert B., Altshuler, David, Voight, Benjamin F.

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Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD) von Bentivegna, Steven, Zheng, Jianbiao, Namsaraev, Eugeni, Carlton, Victoria E.H, Pavlicek, Adam, Moorhead, Martin, Siddiqui, Farooq, Wang, Zhiyong, Lee, Liana, Ireland, James S, Suyenaga, Kent, Willis, Thomas D, Faham, Malek, Seymour, Albert B

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Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis von Meulenbelt, Ingrid, Min, Josine L., Bos, Steffan, Riyazi, Naghmeh, Houwing-Duistermaat, Jeanine J., van der Wijk, Henk-Jan, Kroon, Herman M., Nakajima, Masahiro, Ikegawa, Shiro, Uitterlinden, André G., van Meurs, Joyce B.J., van der Deure, Wendy M., Visser, Theo J., Seymour, Albert B., Lakenberg, Nico, van der Breggen, Ruud, Kremer, Dennis, van Duijn, Cornelia M., Kloppenburg, Margreet, Loughlin, John, Slagboom, P. Eline

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A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype von Malfait, Anne-Marie, Seymour, Albert B, Gao, Feng, Tortorella, Micky D, Le Graverand-Gastineau, Marie-Pierre Hellio, Wood, Linda S, Doherty, Michael, Doherty, Sally, Zhang, Weiya, Arden, Nigel K, Vaughn, Frances L, Leaverton, Paul E, Spector, Tim D, Hart, Deborah J, Maciewicz, Rose A, Muir, Kenneth R, Das, Rosalina, Sorge, Robert E, Sotocinal, Susanna G, Schorscher-Petcu, Ara, Valdes, Ana M, Mogil, Jeffrey S

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Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels von Hinds, David A, Seymour, Albert B, Durham, L Kathryn, Banerjee, Poulabi, Ballinger, Dennis G, Milos, Patrice M, Cox, David R, Thompson, John F, Frazer, Kelly A

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The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder von Durham, L Kathryn, Webb, Suzin M, Milos, Patrice M, Clary, Cathryn M, Seymour, Albert B

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Emerging strategies and applications of pharmacogenomics von Milos, Patrice M, Seymour, Albert B

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p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions von REDSTON, M. S, CALDAS, C, SEYMOUR, A. B, HRUBAN, R. H, DA COSTA, L, YEO, C. J, KERN, S. E

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Homozygous deletion map at 18q21.1 in pancreatic cancer von HAHN, S. A, HOQUE, A. T. M. S, KERN, S. E, MOSKALUK, C. A, DA COSTA, L. T, SCHUTTE, M, ROZENBLUM, E, SEYMOUR, A. B, WEINSTEIN, C. L, YEO, C. J, HRUBAN, R. H

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Allelotype of pancreatic adenocarcinoma von SEYMOUR, A. B, HRUBAN, R. H, REDSTON, M, CALDAS, C, POWELL, S. M, KINZLER, K. W, YEO, C. J, KERN, S. E

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Abnormal Expression and Subcellular Distribution of Subunit Proteins of the AP-3 Adaptor Complex Lead to Platelet Storage Pool Deficiency in the Pearl Mouse von Zhen, Lijie, Jiang, Shelley, Feng, Lijun, Bright, Nicholas A., Peden, Andrew A., Seymour, Albert B., Novak, Edward K., Elliott, Rosemary, Gorin, Michael B., Robinson, Margaret S., Swank, Richard T.

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The β3A Subunit Gene (Ap3B1) of the Ap-3 Adaptor Complex Is Altered in the Mouse Hypopigmentation Mutant Pearl, a Model for Hermansky-Pudlak Syndrome and Night Blindness von Feng, Lijun, Seymour, Albert B., Jiang, Shelley, To, Agnes, Peden, Andrew A., Novak, Edward K., Zhen, Lijie, Rusiniak, Michael E., Eicher, Eva M., Robinson, Margaret S., Gorin, Michael B., Swank, Richard T.

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