Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues von Tjhin, Erick T, Spry, Christina, Sewell, Alan L, Hoegl, Annabelle, Barnard, Leanne, Sexton, Anna E, Siddiqui, Ghizal, Howieson, Vanessa M, Maier, Alexander G, Creek, Darren J, Strauss, Erick, Marquez, Rodolfo, Auclair, Karine, Saliba, Kevin J

Volltext

Metabolomics-Based Elucidation of Active Metabolic Pathways in Erythrocytes and HSC-Derived Reticulocytes von Srivastava, Anubhav, Evans, Krystal J, Sexton, Anna E, Schofield, Louis, Creek, Darren J

Volltext

Post-Genomic Approaches to Understanding Malaria Parasite Biology: Linking Genes to Biological Functions von Sexton, Anna E, Doerig, Christian, Creek, Darren J, Carvalho, Teresa G

Volltext

A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum–infected red blood cell proteome von Siddiqui, Ghizal, De Paoli, Amanda, MacRaild, Christopher A, Sexton, Anna E, Boulet, Coralie, Shah, Anup D, Batty, Mitchell B, Schittenhelm, Ralf B, Carvalho, Teresa G, Creek, Darren J

Volltext

A high parasite density environment induces transcriptional changes and cell death in Plasmodium falciparum blood stages von Chou, Evelyn S., Abidi, Sabia Z., Teye, Marian, Leliwa‐Sytek, Aleksandra, Rask, Thomas S., Cobbold, Simon A., Tonkin‐Hill, Gerry Q., Subramaniam, Krishanthi S., Sexton, Anna E., Creek, Darren J., Daily, Johanna P., Duffy, Michael F., Day, Karen P.

Volltext

Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor von Leach, Katie, Gregory, Karen J, Kufareva, Irina, Khajehali, Elham, Cook, Anna E, Abagyan, Ruben, Conigrave, Arthur D, Sexton, Patrick M, Christopoulos, Arthur

Volltext

Supporting data for "A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum-infected red blood cell proteome" von Ghizal, Siddiqui, De Paoli Amanda, Christopher, MacRaild A, Anna, Sexton E, Coralie, Boulet, Anup, Shah D, Mitchell, Batty B, Ralf, Schittenhelm B, Teresa, Carvalho G, Darren, Creek J

Volltext bestellen

Toxoplasma gondii exploits the host ESCRT machinery for parasite uptake of host cytosolic proteins von Rivera-Cuevas, Yolanda, Mayoral, Joshua, Di Cristina, Manlio, Lawrence, Anna-Lisa E., Olafsson, Einar B., Patel, Romir K., Thornhill, Dishari, Waldman, Benjamin S., Ono, Akira, Sexton, Jonathan Z., Lourido, Sebastian, Weiss, Louis M., Carruthers, Vern B.

Volltext

Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor von Davey, Anna E, Leach, Katie, Valant, Celine, Conigrave, Arthur D, Sexton, Patrick M, Christopoulos, Arthur

Volltext

Impact of Clinically Relevant Mutations on the Pharmacoregulation and Signaling Bias of the Calcium-Sensing Receptor by Positive and Negative Allosteric Modulators von Leach, Katie, Wen, Adriel, Cook, Anna E, Sexton, Patrick M, Conigrave, Arthur D, Christopoulos, Arthur

Volltext

Divergent effects of strontium and calcium‐sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity von Diepenhorst, Natalie A, Leach, Katie, Keller, Andrew N, Rueda, Patricia, Cook, Anna E, Pierce, Tracie L, Nowell, Cameron, Pastoureau, Philippe, Sabatini, Massimo, Summers, Roger J, Charman, William N, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

Volltext

Nrf2 Amplifies Oxidative Stress via Induction of Klf9 von Zucker, Shoshanna N., Fink, Emily E., Bagati, Archis, Mannava, Sudha, Bianchi-Smiraglia, Anna, Bogner, Paul N., Wawrzyniak, Joseph A., Foley, Colleen, Leonova, Katerina I., Grimm, Melissa J., Moparthy, Kalyana, Ionov, Yurij, Wang, Jianmin, Liu, Song, Sexton, Sandra, Kandel, Eugene S., Bakin, Andrei V., Zhang, Yuesheng, Kaminski, Naftali, Segal, Brahm H., Nikiforov, Mikhail A.

Volltext

Identification of Molecular Phenotypes and Biased Signaling Induced by Naturally Occurring Mutations of the Human Calcium-Sensing Receptor von Leach, Katie, Wen, Adriel, Davey, Anna E, Sexton, Patrick M, Conigrave, Arthur D, Christopoulos, Arthur

Volltext

Detection of Tickborne Relapsing Fever Spirochete, Austin, Texas, USA von Bissett, Jack D, Ledet, Suzanne, Krishnavajhala, Aparna, Armstrong, Brittany A, Klioueva, Anna, Sexton, Christopher, Replogle, Adam, Schriefer, Martin E, Lopez, Job E

Volltext

Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H 3 receptor antagonists von Riddy, Darren M, Cook, Anna E, Shackleford, David M, Pierce, Tracie L, Mocaer, Elisabeth, Mannoury la Cour, Clotilde, Sors, Aurore, Charman, William N, Summers, Roger J, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

Volltext

Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists von Riddy, Darren M., Cook, Anna E., Shackleford, David M., Pierce, Tracie L., Mocaer, Elisabeth, Mannoury la Cour, Clotilde, Sors, Aurore, Charman, William N., Summers, Roger J., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J.

Volltext

The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy von Jonsson, Maria Karolina, Hensvold, Aase Haj, Hansson, Monika, Aga, Anna-Birgitte, Sexton, Joseph, Mathsson-Alm, Linda, Cornillet, Martin, Serre, Guy, Lillegraven, Siri, Fevang, Bjørg-Tilde Svanes, Catrina, Anca Irinel, Haavardsholm, Espen Andre

Volltext

Isoform-Specific Biased Agonism of Histamine H3 Receptor Agonists von Riddy, Darren M, Cook, Anna E, Diepenhorst, Natalie A, Bosnyak, Sanja, Brady, Ryan, Mannoury la Cour, Clotilde, Mocaer, Elisabeth, Summers, Roger J, Charman, William N, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

Volltext

Inhibition of somatosensory mechanotransduction by annexin A6 von Raouf, Ramin, Lolignier, Stéphane, Sexton, Jane E, Millet, Queensta, Santana-Varela, Sonia, Biller, Anna, Fuller, Alice M, Pereira, Vanessa, Choudhary, Jyoti S, Collins, Mark O, Moss, Stephen E, Lewis, Richard, Tordo, Julie, Henckaerts, Els, Linden, Michael, Wood, John N

Volltext

Heritable DNA methylation marks associated with susceptibility to breast cancer von Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C.

Volltext