P-018 Study of sperm DNA fragmentation in the infertile population before, during and after the SARS-CoV-2 pandemic: a nationwide retrospective cohort study von Lara-Cerrillo, S, Lacruz-Ruiz, T, Rosado-Iglesias, C, Serrano-Berenguer, L, Garcia-Peiro, A

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P-101 Machine and Deep learning models to classify Comet assay tests for sperm DNA fragmentation evaluation von Serrano Berenguer, L, Hincapié Monsalve, S, Lara Cerrillo, S, Rosado Iglesias, C, Vegas Lozano, E, Reverter Comes, F, Ventura, C, García Peiró, A

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Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway von Sebastián, David, Sorianello, Eleonora, Segalés, Jessica, Irazoki, Andrea, Ruiz-Bonilla, Vanessa, Sala, David, Planet, Evarist, Berenguer-Llergo, Antoni, Muñoz, Juan Pablo, Sánchez-Feutrie, Manuela, Plana, Natàlia, Hernández-Álvarez, María Isabel, Serrano, Antonio L, Palacín, Manuel, Zorzano, Antonio

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Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming von Chondronasiou, Dafni, Gill, Diljeet, Mosteiro, Lluc, Urdinguio, Rocio G., Berenguer‐Llergo, Antonio, Aguilera, Mònica, Durand, Sylvere, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Abad, Maria, Martin‐Herranz, Daniel E., Stephan‐Otto Attolini, Camille, Prats, Neus, Kroemer, Guido, Fraga, Mario F., Reik, Wolf, Serrano, Manuel

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Bioprosthetic Valve Thrombosis and Obstruction Secondary to COVID-19 von Llopis Gisbert, Guillem, Vidal Urrutia, Verónica, Moruno Benita, Miguel A., Payá Chaume, Ana, Berenguer Jofresa, Alberto, Cubillos Arango, Andrés M., Pérez Boscá, José L., Payá Serrano, Rafael

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Reply to Güner et al.—Management of Obstructive Heart Valve Thrombosis: Differences Between Biological and Mechanical Prostheses von Llopis Gisbert, Guillem, Vidal Urrutia, Verónica, Moruno Benita, Miguel A., Payá Chaume, Ana, Berenguer Jofresa, Alberto, Cubillos Arango, Andrés M., Pérez Boscá, José L., Payá Serrano, Rafael

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Reinfection by hepatitis C virus following effective all-oral direct-acting antiviral drug therapy in HIV/hepatitis C virus coinfected individuals von Berenguer, Juan, Gil-Martin, Ángela, Jarrin, Inmaculada, Montes, María L, Domínguez, Lourdes, Aldámiz-Echevarría, Teresa, Téllez, María J, Santos, Ignacio, Troya, Jesús, Losa, Juan E, Serrano, Regino, De Guzmán, María T, Calvo, María J, González-García, Juan J

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A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5 von Gamez-Garcia, Andres, Espinosa-Alcantud, Maria, Bueno-Costa, Alberto, Alari-Pahissa, Elisenda, Marazuela-Duque, Anna, Thackray, Joshua K., Ray, Chandni, Berenguer, Clara, Kumari, Poonam, Bech, Joan Josep, Braun, Thomas, Ianni, Alessandro, Tischfield, Jay A., Serrano, Lourdes, Esteller, Manel, Sardina, Jose L., De La Torre, Carolina, Sigvardsson, Mikael, Vazquez, Berta N., Vaquero, Alejandro

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Prognostic value of multiparametric cardiac magnetic resonance after revascularized STEMI von Igual Munoz, B, Ferre Valverdu, M F V, Miro Palau, V M P, Berenguer Jofesa, A B J, Plaza Lopez, D P L, Melero Ferrer, J M F, Vicente Montagud, V M B, Domenech Tort, D D T, Facila Rubio, L F R, Ridocci Soriano, F R S, Paya Serrano, R P S

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Neoadjuvant treatment in borderline resectable pancreatic adenocarcinoma von Secanella, L., Busquets, J., Peláez, N., Laquente, B., Ruiz, S., Serrano, T., Peiró, I., Berenguer, M.A., Álvarez, A., Fabregat, J.

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The natural history of liver cirrhosis in HIV-hepatitis C virus-coinfected patients von LOPEZ-DIEGUEZ, María, MONTES, María L, ARRIBAS, Jose R, PASCUAL-PAREJA, Jose F, QUEREDA, Carmen, VON WICHMANN, Miguel A, BERENGUER, Juan, TURAL, Cristina, HERNANDO, Asuncion, GONZALEZ-CARCIA, Juan, SERRANO, Lucia

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Outcome of HCV/HIV‐Coinfected Liver Transplant Recipients: A Prospective and Multicenter Cohort Study von Miro, J. M., Montejo, M., Castells, L., Rafecas, A., Moreno, S., Agüero, F., Abradelo, M., Miralles, P., Torre‐Cisneros, J., Pedreira, J. D., Cordero, E., de la Rosa, G., Moyano, B., Moreno, A., Perez, I., Rimola, A.

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965P Role of STAT3 (signal transducer and activator of transcription 3) activation and its regulation by PTPRT (protein receptor tyrosine phosphatase type T) and response to paclit... von Cirauqui Cirauqui, B., Bernat Peguera, A., Quer Pi-Sunyer, A., Ramírez Serrano, J.L., Domenech Viñolas, M., Teruel García, I., Quiroga García, V., Margeli Vila, M., Chaib, I., Capdevila Riera, L., Ferrando Diez, A., Plaja Salarich, A., Angelats Company, L., España Fernandez, S., Berenguer Peinado, G., Lezcano Rubio, C., Pollan Guisasola, C., Martinez Cardús, A., Rosell Costa, R., Mesia Nin, R.

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Limitations of a non-invasive model of the estimation of pulmonary vascular resistance by magnetic resonance imaging in patients with heart failure von Vidal Urrutia, V, Cubillos-Arango, A, Garcia-Gonzalez, P, Gradoli-Palmero, J, Nunez-Villota, J, Facila-Rubio, L, Fernandez-Diaz, C, Abdala-Lizarraga, J, Vilar Herrero, JV, Berenguer-Jofresa, A, Paya Serrano, R, Rumiz-Gonzalez, E

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Reinfection by HCV following effective all-oral DAA therapy in HIV/HCV-coinfected individuals von Berenguer, Juan, Gil-Martin, Ángela, Jarrin, Inmaculada, Montes, María L, Domínguez, Lourdes, Aldámiz-Echevarría, Teresa, Téllez, María J, Santos, Ignacio, Troya, Jesús, Losa, Juan E, Serrano, Regino, De Guzmán, María T, Calvo, María J, González-García, Juan J

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Water table depth modulates productivity and biomass across Amazonian forests von Sousa, Thaiane R, Ribeiro, Igor O, Emílio, Thaise, Fernández, Rafael Herrera, ter Steege, Hans, Esquivel-Muelbert, Adriane, Silva, Camila V.J, Silveira, Juliana M, Castro, Wendeson, Mendoza, Abel Monteagudo, Ruschel, Ademir, Prieto, Adriana, Lima, Adriano José Nogueira, Rudas, Agustín, Araujo-Murakami, Alejandro, Gutierrez, Alexander Parada, Roopsind, Anand, Manzatto, Angelo Gilberto, Di Fiore, Anthony, Dourdain, Aurélie, Marimon, Beatriz, Marimon, Ben Hur, van Ulft, Bert, Herault, Bruno, Quesada, Carlos, Mendoza, Casimiro, Stahl, Clement, Bonal, Damien, Neill, David, de Oliveira, Edmar A, Jimenez-Rojas, Eliana, Alvarez-Davila, Esteban, Almeida, Everton, Coelho, Fernanda, Valverde, Fernando Cornejo, Elias, Fernando, Brown, Foster, Bongers, Frans, Arevalo, Freddy Ramirez, Lopez-Gonzalez, Gabriela, van der Heijden, Geertje, Aymard C., Gerardo A, Ramírez-Angulo, Hirma, do Amaral, Iêda Leão, Vieira, Ima Célia Guimarães, Singh, James, Zwerts, Joeri Alexander, Talbot, Joey, Terborgh, John, Ferreira, Joice, Barlow, Jos, Camargo, José Luís, Stropp, Juliana, Peacock, Julie, Serrano, Julio, Ferreira, Leandro V, Blanc, Lilian, Poorter, Lourens, Gamarra, Luis Valenzuela, Aragão, Luiz, Arroyo, Luzmila, Vargas, Mario Percy Núñez, Toledo, Marisol, Disney, Mat, Réjou-Méchain, Maxime, Baisie, Michel, Kalamandeen, Michelle, Camacho, Nadir Pallqui, Cardozo, Nállarett Dávila, Silva, Natalino, Pitman, Nigel, Higuchi, Niro, Graça, Paulo M.L.A, Morandi, Paulo S, van der Meer, Peter J, van der Hout, Peter, Naisso, Pétrus, Camargo, Plínio Barbosa, Salomão, Rafael, Boot, Rene, da Costa Silva, Richarlly, Burnham, Robyn, Zagt, Roderick, Martinez, Rodolfo Vasquez, Brienen, Roel, Ribeiro, Sabina Cerruto, Lewis, Simon L, Vieira, Simone Aparecida, de Almeida Reis, Simone Matias, Fauset, Sophie, Laurance, Susan, Killeen, Timothy, Wortel, Verginia, Moscoso, Victor Chama, Vos, Vincent, Huasco, Walter Huaraca, Laurance, William, Malhi, Yadvinder, Phillips, Oliver L, Costa, Flávia R.C

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Renal function improvement in liver transplant recipients after early everolimus conversion: A clinical practice cohort study in Spain von Bilbao, Itxarone, Salcedo, Magdalena, Gómez, Miguel Angel, Jimenez, Carlos, Castroagudín, Javier, Fabregat, Joan, Almohalla, Carolina, Herrero, Ignacio, Cuervas‐Mons, Valentín, Otero, Alejandra, Rubín, Angel, Miras, Manuel, Rodrigo, Juan, Serrano, Trinidad, Crespo, Gonzalo, Mata, Manuel De la, Bustamante, Javier, Gonzalez‐Dieguez, M. Luisa, Moreno, Antonia, Narvaez, Isidoro, Guilera, Magda

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Control of Blood Pressure in Liver Transplant Recipients von MARTINEZ-SALDIVAR, Belinda, PRIETO, Jhon, LORENTE, Sara, RUBIN, Angel, FRAGA, Enrique, RIMOLA, Antoni, BERENGUER, Marina, DE LA MATA, Manuel, PONS, José-Antonio, SERRANO, Trinidad, RAFAEL-VALDIVIA, Lourdes, AGUILERA, Victoria, BARRERA, Pilar, PARRILLA, Pascual

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P359 Dipyridamole stress cardiac magnetic resonance in the assessment of utility of coronary revascularization in patients with stable angina von Igual Munoz, B, Maryem Ezzitouny, M E, Elena Sanchez Lacuesta, E S L C, Jose Luis Diez Gil, J L D G, Vicente Miro Palau, V M P, Francisco Ten Morro, F T P, Maria Ferre Valverdu, M F V, Alberto Berenguer Jofesa, A B J, Jose Leandro Perez Bosca, J L P B, Rafael Paya Serrano, R P S

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4CPS-068 Sub-therapeutic plasma levels of linezolid in the icu: usual or unusual in this setting? von Tena, I Puértolas, Serrano, B Bonaga, Gómez, P Luque, Mendoza, M Arenere, Torrijo, N Berenguer, Suescun, L Sáez-Benito, Gómez, T Salvador

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