472P Homologous-recombination deficiency (HRD) in gastroesophageal adenocarcinoma (GEA): Clinical and molecular features von Acosta Eyzaguirre, D., Castillo, G., Aguilar Izquierdo, S., Cruellas Lapena, M., Herencia Ropero, A., Landolfi, S., Palma, H., Tian, T., Vivancos, A., Serra Elizalde, V., Macarulla Mercade, T.

Volltext

779P Assessment of the RAD51 test to determine homologous recombination deficiency (HRD) in patients (pts) with newly diagnosed advanced high-grade epithelial ovarian cancer carcin... von Garcia Duran, C., Domenech, H., Villacampa Javierre, G., Fariñas Madrid, L., Simonetti, S., Illescas, D.G., Serra Elizalde, V., Grau Béjar, J.F., Mazzeo, R., Llop-Guevara, A., Oaknin, A.

Volltext

57TiP SOLTI-1910: Predicting olaparib sensitivity in patients with unresectable locally advanced/metastatic HER2-negative breast cancer with BRCA1/2, PALB2, RAD51C/D mutations or H... von Balmana, J., Pascual, T., Llop-Guevara, A., Tolosa, P., Blancas López-Barajas, I., Perez Lopez, M.E., Adamo, B., Teruel-Garcia, I., Ponce, J., González-Cordero, M., Viñas Villaro, G., Lema Roso, L., Salvador Bofill, F.J., M. Martinez, M.T., Guerrero, A.N.E., Prat, A., Serra Elizalde, V.

Volltext

12P Prevalence of functional and genomic homologous recombination deficiency (HRD) in germline RAD51C/D patients von Llop-Guevara, A., Torres-Esquius, S., Romey, M., Gutierrez-Enriquez, S., Nuciforo, P.G., Diez, O., Llort Pursals, G., Teule, A., Vallmajó, A., Diaz De Corcuera, I., Chirivella Gonzalez, I., Gonzalez Santiago, S., Sanchez Henarejos, P., Sanz Buxo, J., Guillen Ponce, C., Sanchez, A.B., Brunet Vidal, J.M., Denkert, C., Serra Elizalde, V., Balmaña, J.

Volltext

Dissecting the antitumor immune response upon PARP inhibition in homologous recombination repair (HRR)-deficient tumors von Pellegrino, B., Llop-Guevara, A., Cruz, C., Castroviejo, M., Cedro-Tanda, A., Fasani, R., Nuciforo, P.G., Gros, A., Balmaña, J., O'Connor, M.J., Serra Elizalde, V.

Volltext

18PDissecting the antitumor immune response upon PARP inhibition in homologous recombination repair (HRR)-deficient tumors von Pellegrino, B, Llop-Guevara, A, Cruz, C, Castroviejo, M, Cedro-Tanda, A, Fasani, R, Nuciforo, P G, Gros, A, Balmaña, J, O'Connor, M J, Serra Elizalde, V

Volltext

1O Detection of homologous recombination repair deficiency (HRD) in treatment-naive early triple-negative breast cancer (TNBC) by RAD51 foci and comparison with DNA-based tests von Serra Elizalde, V., Llop-Guevara, A., Pearson, A., Cruz, C., Castroviejo-Bermejo, M., Chopra, N., Tovey, H., Toms, C., Kriplani, D., Gevensleben, H., Roylance, R., Chan, S., Tutt, A., Skene, A., Evans, A., Davies, H.R., Bliss, J., Nik-Zainal, S., Balmaña, J., Turner, N.

Volltext

1873O - PARP inhibition increases immune infiltration in homologous recombination repair (HRR)-deficient tumors von Pellegrino, B., Llop-Guevara, A., Pedretti, F., Cruz, C., Castroviejo, M., Cedro-Tanda, A., Fasani, R., Mateo, F., Musolino, A., Pujana, M.A., Nuciforo, P.G., Gros, A., Balmana, J., O’Connor, M.J., Serra Elizalde, V.

Volltext

1873OPARP inhibition increases immune infiltration in homologous recombination repair (HRR)-deficient tumors von Pellegrino, B, Llop-Guevara, A, Pedretti, F, Cruz, C, Castroviejo, M, Cedro-Tanda, A, Fasani, R, Mateo, F, Musolino, A, Pujana, M A, Nuciforo, P G, Gros, A, Balmana, J, O’Connor, M J, Serra Elizalde, V

Volltext

PARP inhibition increases immune infiltration in homologous recombination repair (HRR)-deficient tumors von Pellegrino, B., Llop-Guevara, A., Pedretti, F., Cruz, C., Castroviejo, M., Cedro-Tanda, A., Fasani, R., Mateo, F., Musolino, A., Pujana, M.A., Nuciforo, P.G., Gros, A., Balmana, J., O’Connor, M.J., Serra Elizalde, V.

Volltext

94P Biological effects of a pre-operative radiotherapy boost in early-stage breast cancer: Primary results of the YOUNGSTER unicentric single-arm clinical trial von Gomà, C., Brasó-Maristany, F., Oses, G., Torres, E. Sanfeliu, Hernandez, A. Rodriguez, Gonzalez-Farre, B., Llop-Guevara, A., Elizalde, V. Serra, Ganau, S., Úbeda, B., Bargalló, X., Prat, A., Mollá, M.

Volltext

GDF15 is an Eribulin Response Biomarker also required for Survival of DTP Breast Cancer Cells von Bellio, Chiara, Emperador, Marta, Castellano, Pol, Gris-Oliver, Albert, Canals, Francesc, Sànchez, Àlex (Sànchez Pla), Zamora, Esther, Arribas, Joaquín V. (Vicente), Saura, Cristina, Serra Elizalde, Violeta, Tabernero Caturla, Josep, Littlefield, Bruce A, Villanueva i Cardús, Josep

Volltext

Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago von Petracca, GL, Teixeira Gonzaga, RA, Pereira, BM, Augustin, G, De Simone, B, Panis, Y, Roulet, M, Merabishvili, G, Doudakmanis, C, Margaris, I, Bourbouteli, E, Kavalieratos, G, Anestiadou, E, Martines, G, Trigiante, G, Lantone, G, Lovisetto, F, Perrone, F, Picciariello, A, Visconti, D, D'Alessio, R, Musa, N, D'Acapito, F, Solaini, L, Borghi, F, Sena, G, Portale, G, Isernia, RM, Bernardi, DT, Bonilauri, S, Biloslavo, A, Chahrour, AC, Fransvea, P, Bianchi, V, Gattulli, D, Cannavera, A, Spampinato, M, Rampini, A, Totaro, L, Capolupo, GT, Scheiterle, M, Ceresoli, M, Balla, A, Lepiane, P, Ambrosi, A, Bertoli, P, Spolini, A, Kryzauskas, M, Zakaria, AD, Cruz, DR, Hernandez, EEL, Latorraca, J, Pedziwiatr, M, Kwiatkowski, A, Pereira, B, Carneiro, C, Perez, DP, Goulart, A, Pereira, RG, Miron, A, Gachabayov, M, Abdullaev, A, Nechay, T, Morales-Sevillano, X, Mingoli, A, Del Pozo, EP, Dos Barbeito, S, Rahy-Martin, AC, Mendoza-Moreno, F, Gonzalez-Castillo, AM, Ruiz Moreno, C, Rubio Garcia, JJ, Santamaria Gomez, M, Mestres Petit, N, Sebastian-Tomas, JC, Jimenez-Vega, J, Blanco Antona, F, Lora Cumplido, P, Duran Martinez, M, Cloquell, MM, Mongkhonsupphawan, A, Ayed, K, Zribi, I, Koylu, ZA, Mantoglu, B, Isik, A, Kara, Y, Kocatas, A, Kaya, T, Altinel, Y, Meric, S, Rana, M, Delgado, E, Edwards, S, Coffua, LS, McClure, A, Cairl, N, Biffl, WL, Schaffer, K, Reames, S

Volltext

Cancer network activity associated with therapeutic response and synergism von Serra-Musach, Jordi, Mateo González, Francesca, Capdevila Busquets, Eva, Ruiz de Garibay, Gorka, Zhang, Xiaohu, Guha, Raj, Thomas, Craig J, Grueso, Judit, Villanueva Garatachea, Alberto, Jaeger, Samira, Heyn, Holger, Vizoso, Miguel, Pérez-Montoyo, Hector, Cordero, Alex, González Suárez, Eva, Esteller, Manel, Moreno-Bueno, Gema, Tjärnberg, Andreas, Lázaro García, Conxi, Serra Elizalde, Violeta, Arribas, Joaquín V. (Vicente), Benson, Mikael, Gustafsson, Mika, Ferrer, Marc, Aloy, Patrick, 1972, Pujana Genestar, M. Ángel

Volltext

BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance von Wang, Yifan, Bernhardy, Andrea J, Nacson, Joseph, Krais, John J, Tan, Yin-Fei, Nicolas, Emmanuelle, Llop Guevara, Alba, Balmaña Gelpí, Judith, Serra Elizalde, Violeta

Volltext bestellen

Interrogating open issues in cancer precision medicine with patient-derived xenografts von Byrne, Annette T, Alférez, Denis G, Amant, Frédéric, Annibali, Daniela, Arribas, Joaquín V. (Vicente), Biankin, Andrew V, Bruna, Alejandra, Budinská, Eva, Caldas, Carlos, Chang, David K, Clarke, Robert B, Clevers, Hans, Coukos, George, Dangles Marie, Virginie, Eckhardt, S. Gail, González Suárez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A, Jong, Steven de, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Mælandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean-Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Héctor G, Peeper, Daniel S, Pelicci, Pier Giuseppe, Piris Gimenez, Alejandro, Roman Roman, Sergio, Rueda, Oscar M, Seoane Suárez, Joan, Serra Elizalde, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva Garatachea, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio

Volltext bestellen