CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data von Serin Harmanci, Akdes, Harmanci, Arif O., Zhou, Xiaobo

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METAP1 mutation is a novel candidate for autosomal recessive intellectual disability von Caglayan, Ahmet Okay, Aktar, Fesih, Bilguvar, Kaya, Baranoski, Jacob F, Akgumus, Gozde Tugce, Harmanci, Akdes Serin, Erson-Omay, Emine Zeynep, Yasuno, Katsuhito, Caksen, Huseyin, Gunel, Murat

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Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation von Curry, Rachel Naomi, Aiba, Isamu, Meyer, Jochen, Lozzi, Brittney, Ko, Yeunjung, McDonald, Malcolm Ford, Rosenbaum, Anna, Cervantes, Alexis, Huang-Hobbs, Emmet, Cocito, Carolina, Greenfield, Jeffrey Peter, Jalali, Ali, Gavvala, Jay, Mohila, Carrie, Serin Harmanci, Akdes, Noebels, Jeffrey, Rao, Ganesh, Deneen, Benjamin

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XCVATR: detection and characterization of variant impact on the Embeddings of single -cell and bulk RNA-sequencing samples von Harmanci, Arif, Harmanci, Akdes Serin, Klisch, Tiemo J, Patel, Akash J

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Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma von Curry, Rachel N., Ma, Qianqian, McDonald, Malcolm F., Ko, Yeunjung, Srivastava, Snigdha, Chin, Pey-Shyuan, He, Peihao, Lozzi, Brittney, Athukuri, Prazwal, Jing, Junzhan, Wang, Su, Harmanci, Arif O., Arenkiel, Benjamin, Jiang, Xiaolong, Deneen, Benjamin, Rao, Ganesh, Serin Harmanci, Akdes

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CXCR4 expression is associated with proneural‐to‐mesenchymal transition in glioblastoma von Khan, A. Basit, Lee, Sungho, Harmanci, Akdes Serin, Patel, Rajan, Latha, Khatri, Yang, Yuhui, Marisetty, Anantha, Lee, Hyun‐Kyoung, Heimberger, Amy B., Fuller, Gregory N., Deneen, Benjamin, Rao, Ganesh

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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma von Rajendran, Sakthi, Hu, Yang, Canella, Alessandro, Peterson, Clayton, Gross, Amy, Cam, Maren, Nazzaro, Matthew, Haffey, Abigail, Serin-Harmanci, Akdes, Distefano, Rosario, Nigita, Giovanni, Wang, Wesley, Kreatsoulas, Daniel, Li, Zihai, Sepeda, Jesse A., Sas, Andrew, Hester, Mark E., Miller, Katherine E., Elemento, Olivier, Roberts, Ryan D., Holland, Eric C., Rao, Ganesh, Mardis, Elaine R., Rajappa, Prajwal

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NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy von Caglayan, Ahmet Okay, Comu, Sinan, Baranoski, Jacob F, Parman, Yesim, Kaymakçalan, Hande, Akgumus, Gozde Tugce, Caglar, Caner, Dolen, Duygu, Erson-Omay, Emine Zeynep, Harmanci, Akdes Serin, Mishra-Gorur, Ketu, Freeze, Hudson H, Yasuno, Katsuhito, Bilguvar, Kaya, Gunel, Murat

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Longitudinal analysis of treatment-induced genomic alterations in gliomas von Erson-Omay, E Zeynep, Henegariu, Octavian, Omay, S Bülent, Harmancı, Akdes Serin, Youngblood, Mark W, Mishra-Gorur, Ketu, Li, Jie, Özduman, Koray, Carrión-Grant, Geneive, Clark, Victoria E, Çağlar, Caner, Bakırcıoğlu, Mehmet, Pamir, M Necmettin, Tabar, Viviane, Vortmeyer, Alexander O, Bilguvar, Kaya, Yasuno, Katsuhito, DeAngelis, Lisa M, Baehring, Joachim M, Moliterno, Jennifer, Günel, Murat

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Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas von Clark, Victoria E, Harmancı, Akdes Serin, Bai, Hanwen, Youngblood, Mark W, Lee, Tong Ihn, Baranoski, Jacob F, Ercan-Sencicek, A Gulhan, Abraham, Brian J, Weintraub, Abraham S, Hnisz, Denes, Simon, Matthias, Krischek, Boris, Erson-Omay, E Zeynep, Henegariu, Octavian, Carrión-Grant, Geneive, Mishra-Gorur, Ketu, Durán, Daniel, Goldmann, Johanna E, Schramm, Johannes, Goldbrunner, Roland, Piepmeier, Joseph M, Vortmeyer, Alexander O, Günel, Jennifer Moliterno, Bilgüvar, Kaya, Yasuno, Katsuhito, Young, Richard A, Günel, Murat

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Integrated genomic analyses of de novo pathways underlying atypical meningiomas von Harmancı, Akdes Serin, Youngblood, Mark W., Clark, Victoria E., Coşkun, Süleyman, Henegariu, Octavian, Duran, Daniel, Erson-Omay, E. Zeynep, Kaulen, Leon D., Lee, Tong Ihn, Abraham, Brian J., Simon, Matthias, Krischek, Boris, Timmer, Marco, Goldbrunner, Roland, Omay, S. Bülent, Baranoski, Jacob, Baran, Burçin, Carrión-Grant, Geneive, Bai, Hanwen, Mishra-Gorur, Ketu, Schramm, Johannes, Moliterno, Jennifer, Vortmeyer, Alexander O., Bilgüvar, Kaya, Yasuno, Katsuhito, Young, Richard A., Günel, Murat

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Integrated genomic characterization of IDH1-mutant glioma malignant progression von Bai, Hanwen, Harmancı, Akdes Serin, Erson-Omay, E Zeynep, Li, Jie, Coşkun, Süleyman, Simon, Matthias, Krischek, Boris, Özduman, Koray, Omay, S Bülent, Sorensen, Eric A, Turcan, Şevin, Bakırcığlu, Mehmet, Carrión-Grant, Geneive, Murray, Phillip B, Clark, Victoria E, Ercan-Sencicek, A Gulhan, Knight, James, Sencar, Leman, Altınok, Selin, Kaulen, Leon D, Gülez, Burcu, Timmer, Marco, Schramm, Johannes, Mishra-Gorur, Ketu, Henegariu, Octavian, Moliterno, Jennifer, Louvi, Angeliki, Chan, Timothy A, Tannheimer, Stacey L, Pamir, M Necmettin, Vortmeyer, Alexander O, Bilguvar, Kaya, Yasuno, Katsuhito, Günel, Murat

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PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans von Barak, Tanyeri, Ristori, Emma, Ercan-Sencicek, A. Gulhan, Miyagishima, Danielle F., Nelson-Williams, Carol, Dong, Weilai, Jin, Sheng Chih, Prendergast, Andrew, Armero, William, Henegariu, Octavian, Erson-Omay, E. Zeynep, Harmancı, Akdes Serin, Guy, Mikhael, Gültekin, Batur, Kilic, Deniz, Rai, Devendra K., Goc, Nükte, Aguilera, Stephanie Marie, Gülez, Burcu, Altinok, Selin, Ozcan, Kent, Yarman, Yanki, Coskun, Süleyman, Sempou, Emily, Deniz, Engin, Hintzen, Jared, Cox, Andrew, Fomchenko, Elena, Jung, Su Woong, Ozturk, Ali Kemal, Louvi, Angeliki, Bilgüvar, Kaya, Connolly, E. Sander, Khokha, Mustafa K., Kahle, Kristopher T., Yasuno, Katsuhito, Lifton, Richard P., Mishra-Gorur, Ketu, Nicoli, Stefania, Günel, Murat

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Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis von Erson-Omay, E Zeynep, Çağlayan, Ahmet Okay, Schultz, Nikolaus, Weinhold, Nils, Omay, S Bülent, Özduman, Koray, Köksal, Yavuz, Li, Jie, Serin Harmancı, Akdes, Clark, Victoria, Carrión-Grant, Geneive, Baranoski, Jacob, Çağlar, Caner, Barak, Tanyeri, Coşkun, Süleyman, Baran, Burçin, Köse, Doğan, Sun, Jia, Bakırcıoğlu, Mehmet, Moliterno Günel, Jennifer, Pamir, M Necmettin, Mishra-Gorur, Ketu, Bilguvar, Kaya, Yasuno, Katsuhito, Vortmeyer, Alexander, Huttner, Anita J, Sander, Chris, Günel, Murat

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Social deprivation induces astrocytic TRPA1-GABA suppression of hippocampal circuits von Cheng, Yi-Ting, Woo, Junsung, Luna-Figueroa, Estefania, Maleki, Ehson, Harmanci, Akdes Serin, Deneen, Benjamin

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EpiSAFARI: sensitive detection of valleys in epigenetic signals for enhancing annotations of functional elements von Harmanci, Arif, Harmanci, Akdes Serin, Swaminathan, Jyothishmathi, Gopalakrishnan, Vidya

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Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas von Youngblood, Mark W., Erson-Omay, Zeynep, Li, Chang, Najem, Hinda, Coșkun, Süleyman, Tyrtova, Evgeniya, Montejo, Julio D., Miyagishima, Danielle F., Barak, Tanyeri, Nishimura, Sayoko, Harmancı, Akdes Serin, Clark, Victoria E., Duran, Daniel, Huttner, Anita, Avşar, Timuçin, Bayri, Yasar, Schramm, Johannes, Boetto, Julien, Peyre, Matthieu, Riche, Maximilien, Goldbrunner, Roland, Amankulor, Nduka, Louvi, Angeliki, Bilgüvar, Kaya, Pamir, M. Necmettin, Özduman, Koray, Kilic, Türker, Knight, James R., Simon, Matthias, Horbinski, Craig, Kalamarides, Michel, Timmer, Marco, Heimberger, Amy B., Mishra-Gorur, Ketu, Moliterno, Jennifer, Yasuno, Katsuhito, Günel, Murat

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CNSC-23. ROLE OF GLIAL PH-DEPENDENT METABOLIC REGULATION IN GLIOMA PROGRESSION von Ye, Qi, Oh, Heavin, Choy, Tiffany, Madamba, Christine, Serin-Harmanci, Akdes, Rao, Ganesh, Lee, Hyun Kyoung

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EXTH-47. ENHANCING GD2.CART THERAPY FOR DIFFUSE MIDLINE GLIOMA WITH LSD1 AND HDAC INHIBITORS von Murdaugh, Rebecca, Shekar, Meghan, Eberl, Brittany, Tremblay, Jack, Richard, Rosemary, Harmanci, Akdes Serin, Omer, Bilal, Anastas, Jamie

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Inhibitory input directs astrocyte morphogenesis through glial GABABR von Cheng, Yi-Ting, Luna-Figueroa, Estefania, Woo, Junsung, Chen, Hsiao-Chi, Lee, Zhung-Fu, Harmanci, Akdes Serin, Deneen, Benjamin

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