function of RNA-binding proteins at the synapse: implications for neurodegeneration von Sephton, Chantelle F, Yu, Gang

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Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration von Cenik, Basar, Sephton, Chantelle F., Kutluk Cenik, Bercin, Herz, Joachim, Yu, Gang

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Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease von Gelon, Pauline A., Dutchak, Paul A., Sephton, Chantelle F.

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TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor von Dewey, Colleen M., Cenik, Basar, Sephton, Chantelle F., Dries, Daniel R., Mayer, Paul, Good, Shannon K., Johnson, Brett A., Herz, Joachim, Yu, Gang

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Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes von Sephton, Chantelle F., Cenik, Can, Kucukural, Alper, Dammer, Eric B., Cenik, Basar, Han, YuHong, Dewey, Colleen M., Roth, Frederick P., Herz, Joachim, Peng, Junmin, Moore, Melissa J., Yu, Gang

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TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development von Sephton, Chantelle F., Good, Shannon K., Atkin, Stan, Dewey, Colleen M., Mayer, Paul, Herz, Joachim, Yu, Gang

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FUS contributes to mTOR-dependent inhibition of translation von Sévigny, Myriam, Bourdeau Julien, Isabelle, Venkatasubramani, Janani Priya, Hui, Jeremy B., Dutchak, Paul A., Sephton, Chantelle F.

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TDP-43 aggregation in neurodegeneration: Are stress granules the key? von Dewey, Colleen M, Cenik, Basar, Sephton, Chantelle F, Johnson, Brett A, Herz, Joachim, Yu, Gang

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GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1 von Muller, Maéline, Bélanger, Jasmine, Hadj-Aissa, Imane, Zhang, Conghao, Sephton, Chantelle F, Dutchak, Paul A

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis von Sephton, Chantelle F., Tang, Amy A., Kulkarni, Ashwinikumar, West, James, Brooks, Mieu, Stubblefield, Jeremy J., Liu, Yun, Zhang, Michael Q., Green, Carla B., Huber, Kimberly M., Huang, Eric J., Herz, Joachim, Yu, Gang

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Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways von Bittar, Thibault P., Pelaez, Mari Carmen, Hernandez Silva, Jose Cesar, Quessy, Francis, Lavigne, Andrée-Anne, Morency, Daphnée, Blanchette, Léa-Jeanne, Arsenault, Eric, Cherasse, Yoan, Seigneur, Josée, Timofeev, Igor, Sephton, Chantelle F., Proulx, Christophe D., Labonté, Benoit

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TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration von Sephton, Chantelle F., Cenik, Basar, Cenik, Bercin Kutluk, Herz, Joachim, Yu, Gang

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Metabolic Networks Influencing Skeletal Muscle Fiber Composition von Bourdeau Julien, Isabelle, Sephton, Chantelle F, Dutchak, Paul A

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Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD von Ward, Michael E, Taubes, Alice, Chen, Robert, Miller, Bruce L, Sephton, Chantelle F, Gelfand, Jeffrey M, Minami, Sakura, Boscardin, John, Martens, Lauren Herl, Seeley, William W, Yu, Gang, Herz, Joachim, Filiano, Anthony J, Arrant, Andrew E, Roberson, Erik D, Kraft, Timothy W, Farese, Jr, Robert V, Green, Ari, Gan, Li

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Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS von Fernández Comaduran, Mario, Minotti, Sandra, Jacob-Tomas, Suleima, Rizwan, Javeria, Larochelle, Nancy, Robitaille, Richard, Sephton, Chantelle F, Vera, Maria, Nalbantoglu, Josephine N, Durham, Heather D

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Reversal of cognitive deficits in FUSR521G amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction von Pelaez, Mari Carmen, Fiore, Frédéric, Larochelle, Nancy, Dabbaghizadeh, Afrooz, Comaduran, Mario Fernández, Arbour, Danielle, Minotti, Sandra, Marcadet, Laetitia, Semaan, Martine, Robitaille, Richard, Nalbantoglu, Josephine N., Sephton, Chantelle F., Durham, Heather D.

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Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition von Pelaez, Mari Carmen, Desmeules, Antoine, Gelon, Pauline A., Glasson, Bastien, Marcadet, Laetitia, Rodgers, Alicia, Phaneuf, Daniel, Pozzi, Silvia, Dutchak, Paul A., Julien, Jean-Pierre, Sephton, Chantelle F.

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hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated von Gagné, Myriam, Deshaies, Jade-Emmanuelle, Sidibé, Hadjara, Benchaar, Yousri, Arbour, Danielle, Dubinski, Alicia, Litt, Gurleen, Peyrard, Sarah, Robitaille, Richard, Sephton, Chantelle F., Vande Velde, Christine

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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation von Aggarwal, Geetika, Banerjee, Subhashis, Jones, Spencer A., Benchaar, Yousri, Bélanger, Jasmine, Sévigny, Myriam, Smith, Denise M., Niehoff, Michael L., Pavlack, Monica, de Vera, Ian Mitchelle S., Petkau, Terri L., Leavitt, Blair R., Ling, Karen, Jafar-Nejad, Paymaan, Rigo, Frank, Morley, John E., Farr, Susan A., Dutchak, Paul A., Sephton, Chantelle F., Nguyen, Andrew D.

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Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia von Cenik, Basar, Sephton, Chantelle F, Dewey, Colleen M, Xian, Xunde, Wei, Shuguang, Yu, Kimberley, Niu, Wenze, Coppola, Giovanni, Coughlin, Sarah E, Lee, Suzee E, Dries, Daniel R, Almeida, Sandra, Geschwind, Daniel H, Gao, Fen-Biao, Miller, Bruce L, Farese, Jr, Robert V, Posner, Bruce A, Yu, Gang, Herz, Joachim

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