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    Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer von Ferreira, Manuel A., Andrulis, Irene L., Anton-Culver, Hoda, Aronson, Kristan J., Barnes, Daniel R., Beckmann, Matthias W., Behrens, Sabine, Bermisheva, Marina, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Brauch, Hiltrud, Campa, Daniele, Campbell, Ian, Canzian, Federico, Carter, Jonathan, Castelao, Jose E., Chang-Claude, Jenny, Couch, Fergus J., Cox, Angela, Cross, Simon S., de la Hoya, Miguel, Dennis, Joe, Devilee, Peter, Dörk, Thilo, Ejlertsen, Bent, Engel, Christoph, Eriksson, Mikael, Fletcher, Olivia, Flyger, Henrik, Frost, Debra, Gabrielson, Marike, Gapstur, Susan M., Garber, Judy, García-Sáenz, José A., Giles, Graham G., Glendon, Gord, Godwin, Andrew K., González-Neira, Anna, Gronwald, Jacek, Guénel, Pascal, Hall, Per, Hamann, Ute, He, Wei, Hulick, Peter J., Humphreys, Keith, Isaacs, Claudine, Jakimovska, Milena, Jakubowska, Anna, James, Paul A., John, Esther M., Johnson, Nichola, Karlan, Beth Y., Khusnutdinova, Elza, Kiiski, Johanna I., Jones, Michael E., Konstantopoulou, Irene, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Lindström, Sara, Manoochehri, Mehdi, Margolin, Sara, McGuffog, Lesley, Michailidou, Kyriaki, Montagna, Marco, Moreno, Fernando, Moserle, Lidia, Nevelsteen, Ines, Nussbaum, Robert L., Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I., Osorio, Ana, Park-Simon, Tjoung-Won, Pedersen, Inge Sokilde, Peixoto, Ana, Peterlongo, Paolo, Poppe, Bruce, Presneau, Nadege, Risch, Harvey A., Saloustros, Emmanouil, Sanden, Kristin, Simard, Jacques, Singer, Christian F., Soucy, Penny, Spinelli, John J., Spurdle, Amanda B., Taylor, Jack A., Thöne, Kathrin, Toland, Amanda E., Tung, Nadine, Vachon, Celine M., van Asperen, Christi J., van Rensburg, Elizabeth J., Weitzel, Jeffrey N., Winqvist, Robert, Yannoukakos, Drakoulis, Zheng, Wei, Beesley, Jonathan

    Veröffentlicht in NATURE COMMUNICATIONS

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    The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA... von Lakeman, Inge M. M., Vos, Juliën A. M., Barnes, Daniel R., Adlard, Julian, Andrulis, Irene L., Arason, Adalgeir, Arnold, Norbert, Arun, Banu K., Balmaña, Judith, Barrowdale, Daniel, Benitez, Javier, Borg, Ake, Caldés, Trinidad, Caligo, Maria A., Chung, Wendy K., Claes, Kathleen B. M., Collée, J. Margriet, Couch, Fergus J., Daly, Mary B., Dennis, Joe, Dhawan, Mallika, Domchek, Susan M., Eeles, Ros, Engel, Christoph, Evans, D. Gareth, Feliubadaló, Lidia, Foretova, Lenka, Friedman, Eitan, Frost, Debra, Ganz, Patricia A., Gayther, Simon A., Gerdes, Anne-Marie, Godwin, Andrew K., Goldgar, David E., Hahnen, Eric, Hake, Christopher R., Hamann, Ute, Hogervorst, Frans B. L., Hooning, Maartje J., Hopper, John L., Hulick, Peter J., Imyanitov, Evgeny N., Isaacs, Claudine, Izatt, Louise, Jakubowska, Anna, James, Paul A., Janavicius, Ramunas, Jensen, Uffe Birk, Jiao, Yue, John, Esther M., Karlan, Beth Y., Kets, Carolien M., Kwong, Ava, Legrand, Clémentine, Leslie, Goska, Lesueur, Fabienne, Loud, Jennifer T., Manoukian, Siranoush, McGuffog, Lesley, Miller, Austin, Gomes, Denise Molina, Montagna, Marco, Mouret-Fourme, Emmanuelle, Neuhausen, Susan L., Nevanlinna, Heli, Yie, Joanne Ngeow Yuen, Olah, Edith, Olopade, Olufunmilayo I., Park, Sue K., Parsons, Michael T., Peterlongo, Paolo, Radice, Paolo, Rantala, Johanna, Rennert, Gad, Schmutzler, Rita K., Sharma, Priyanka, Simard, Jacques, Singer, Christian F., Stadler, Zsofia, Stoppa-Lyonnet, Dominique, Sutter, Christian, Tan, Yen Yen, Teixeira, Manuel R., Teo, Soo Hwang, Teulé, Alex, Thomassen, Mads, Thull, Darcy L., Tischkowitz, Marc, Toland, Amanda E., Tung, Nadine, Vega, Ana, Wappenschmidt, Barbara, Devilee, Peter, van Asperen, Christi J., Bernstein, Jonine L., Offit, Kenneth, Easton, Douglas F., Rookus, Matti A., Chenevix-Trench, Georgia, Schmidt, Marjanka K.

    Veröffentlicht in Genetics in medicine

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    Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium von Milne, Roger L, Burwinkel, Barbara, Michailidou, Kyriaki, Arias-Perez, Jose-Ignacio, Zamora, M Pilar, Menéndez-Rodríguez, Primitiva, Hardisson, David, Mendiola, Marta, González-Neira, Anna, Pita, Guillermo, Alonso, M Rosario, Dennis, Joe, Wang, Qin, Bolla, Manjeet K, Swerdlow, Anthony, Ashworth, Alan, Orr, Nick, Schoemaker, Minouk, Ko, Yon-Dschun, Brauch, Hiltrud, Hamann, Ute, Andrulis, Irene L, Knight, Julia A, Glendon, Gord, Tchatchou, Sandrine, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Li, Jingmei, Brand, Judith S, Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Stegmaier, Christa, Lambrechts, Diether, Peuteman, Gilian, Christiaens, Marie-Rose, Smeets, Ann, Jakubowska, Anna, Lubinski, Jan, Jaworska-Bieniek, Katarzyna, Durda, Katazyna, Hartman, Mikael, Hui, Miao, Yen Lim, Wei, Wan Chan, Ching, Marme, Federick, Yang, Rongxi, Bugert, Peter, Lindblom, Annika, Margolin, Sara, García-Closas, Montserrat, Chanock, Stephen J, Lissowska, Jolanta, Figueroa, Jonine D, Bojesen, Stig E, Nordestgaard, Børge G, Flyger, Henrik, Hooning, Maartje J, Kriege, Mieke, van den Ouweland, Ans M W, Koppert, Linetta B, Fletcher, Olivia, Johnson, Nichola, dos-Santos-Silva, Isabel, Peto, Julian, Zheng, Wei, Deming-Halverson, Sandra, Shrubsole, Martha J, Long, Jirong, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Cox, Angela, Cross, Simon S, Reed, Malcolm W R, Schmidt, Marjanka K, Broeks, Annegien, Cornelissen, Sten, Braaf, Linde, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K, Noh, Dong-Young, Simard, Jacques, Dumont, Martine, Goldberg, Mark S, Labrèche, France, Fasching, Peter A, Hein, Alexander, Ekici, Arif B, Beckmann, Matthias W, Radice, Paolo, Peterlongo, Paolo

    Veröffentlicht in Human molecular genetics

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    Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer von Gaudet, Mia M, Kirchhoff, Tomas, Green, Todd, Vijai, Joseph, Korn, Joshua M, Guiducci, Candace, Segrè, Ayellet V, McGee, Kate, McGuffog, Lesley, Kartsonaki, Christiana, Morrison, Jonathan, Healey, Sue, Sinilnikova, Olga M, Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Gauthier-Villars, Marion, Sobol, Hagay, Longy, Michel, Frenay, Marc, GEMO Study Collaborators, Hogervorst, Frans B L, Rookus, Matti A, Collée, J Margriet, Hoogerbrugge, Nicoline, van Roozendaal, Kees E P, Piedmonte, Marion, Rubinstein, Wendy, Nerenstone, Stacy, Van Le, Linda, Blank, Stephanie V, Caldés, Trinidad, de la Hoya, Miguel, Nevanlinna, Heli, Aittomäki, Kristiina, Lazaro, Conxi, Blanco, Ignacio, Arason, Adalgeir, Johannsson, Oskar T, Barkardottir, Rosa B, Devilee, Peter, Olopade, Olofunmilayo I, Neuhausen, Susan L, Wang, Xianshu, Fredericksen, Zachary S, Peterlongo, Paolo, Manoukian, Siranoush, Barile, Monica, Viel, Alessandra, Radice, Paolo, Phelan, Catherine M, Narod, Steven, Rennert, Gad, Lejbkowicz, Flavio, Flugelman, Anath, Andrulis, Irene L, Glendon, Gord, Ozcelik, Hilmi, Toland, Amanda E, Montagna, Marco, D'Andrea, Emma, Friedman, Eitan, Laitman, Yael, Borg, Ake, Beattie, Mary, Ramus, Susan J, Domchek, Susan M, Nathanson, Katherine L, Rebbeck, Tim, Spurdle, Amanda B, Chen, Xiaoqing, Holland, Helene, John, Esther M, Hopper, John L, Buys, Saundra S, Daly, Mary B, Southey, Melissa C, Terry, Mary Beth, Tung, Nadine, Overeem Hansen, Thomas V, Nielsen, Finn C, Greene, Mark H, Greene, Mark I, Mai, Phuong L, Osorio, Ana, Durán, Mercedes, Andres, Raquel, Benítez, Javier, Weitzel, Jeffrey N, Garber, Judy, Hamann, Ute, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Platte, Radka, Evans, D Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Walker, Lisa

    Veröffentlicht in PLoS genetics

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    Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers von Antoniou, Antonis C., Sinilnikova, Olga M., McGuffog, Lesley, Healey, Sue, Nevanlinna, Heli, Chen, Xiaoqing, Neuhausen, Susan L., Ding, Yuan C., Couch, Fergus J., Wang, Xianshu, Fredericksen, Zachary, Peterlongo, Paolo, Peissel, Bernard, Viel, Alessandra, Radice, Paolo, Szabo, Csilla I., Foretova, Lenka, Zikan, Michal, Claes, Kathleen, Greene, Mark H., Mai, Phuong L., Ozcelik, Hilmi, Thomassen, Mads, Sunde, Lone, Caligo, Maria A., Laitman, Yael, Kontorovich, Tair, Kaufman, Bella, Dagan, Efrat, Baruch, Ruth Gershoni, Harbst, Katja, Barbany-Bustinza, Gisela, Rantala, Johanna, Domchek, Susan M., Nathanson, Katherine L., Osorio, Ana, Blanco, Ignacio, Lasa, Adriana, Hamann, Ute, Rookus, Matti A., Collee, J. Margriet, Devilee, Peter, van der Luijt, Rob B., Waisfisz, Quinten, Wijnen, Juul, van Roozendaal, Cornelis E.P., Peock, Susan, Cook, Margaret, Frost, Debra, Oliver, Clare, Platte, Radka, Evans, D. Gareth, Eeles, Rosalind, Izatt, Louise, Eccles, Diana, Cole, Trevor, Hodgson, Shirley, Buecher, Bruno, Léoné, Mélanie, Remenieras, Audrey, Caron, Olivier, Lenoir, Gilbert M., Sevenet, Nicolas, Longy, Michel, Ferrer, Sandra Fert, Prieur, Fabienne, Goldgar, David, Miron, Alexander, John, Esther M., Daly, Mary B., Hopper, John L., Gschwantler-Kaulich, Daphne, Staudigl, Christine, Hansen, Thomas v. O., Barkardottir, Rosa Bjork, Kirchhoff, Tomas, Pal, Prodipto, Kosarin, Kristi, Offit, Kenneth, Piedmonte, Marion, Rodriguez, Gustavo C., Wakeley, Katie, Boggess, John F., Schwartz, Peter E., Montagna, Marco, Imyanitov, Evgeny N., Allavena, Anna, Schmutzler, Rita K., Versmold, Beatrix, Engel, Christoph, Ditsch, Nina, Niederacher, Dieter, Deißler, Helmut, Fiebig, Britta, Suttner, Christian, Schönbuchner, Ines, Gadzicki, Dorothea, Caldes, Trinidad, Pooley, Karen A., Chenevix-Trench, Georgia

    Veröffentlicht in Human molecular genetics

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    Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 von Kirchhoff, Tomas, Gaudet, Mia M, Antoniou, Antonis C, McGuffog, Lesley, Humphreys, Manjeet K, Dunning, Alison M, Bojesen, Stig E, Nordestgaard, Børge G, Flyger, Henrik, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Dork, Thilo, Schürmann, Peter, Karstens, Johann H, Hillemanns, Peter, Couch, Fergus J, Olson, Janet, Vachon, Celine, Wang, Xianshu, Cox, Angela, Brock, Ian, Elliott, Graeme, Reed, Malcolm W R, Burwinkel, Barbara, Meindl, Alfons, Brauch, Hiltrud, Hamann, Ute, Ko, Yon-Dschun, Broeks, Annegien, Schmidt, Marjanka K, Van 't Veer, Laura J, Braaf, Linde M, Johnson, Nichola, Fletcher, Olivia, Gibson, Lorna, Peto, Julian, Turnbull, Clare, Seal, Sheila, Renwick, Anthony, Rahman, Nazneen, Wu, Pei-Ei, Yu, Jyh-Cherng, Hsiung, Chia-Ni, Shen, Chen-Yang, Southey, Melissa C, Hopper, John L, Hammet, Fleur, Van Dorpe, Thijs, Dieudonne, Anne-Sophie, Hatse, Sigrid, Lambrechts, Diether, Andrulis, Irene L, Bogdanova, Natalia, Antonenkova, Natalia, Rogov, Juri I, Prokofieva, Daria, Bermisheva, Marina, Khusnutdinova, Elza, van Asperen, Christi J, Tollenaar, Robert A E M, Hooning, Maartje J, Devilee, Peter, Margolin, Sara, Lindblom, Annika, Milne, Roger L, Arias, José Ignacio, Zamora, M Pilar, Benítez, Javier, Severi, Gianluca, Baglietto, Laura, Giles, Graham G, Spurdle, Amanda B, Beesley, Jonathan, Chen, Xiaoqing, Holland, Helene, Healey, Sue, Wang-Gohrke, Shan, Chang-Claude, Jenny, Mannermaa, Arto, Kosma, Veli-Matti, Kauppinen, Jaana, Kataja, Vesa, Agnarsson, Bjarni A, Caligo, Maria A, Godwin, Andrew K, Nevanlinna, Heli, Heikkinen, Tuomas, Fredericksen, Zachary, Lindor, Noralane, Nathanson, Katherine L, Domchek, Susan M, Loman, Niklas, Karlsson, Per, Stenmark Askmalm, Marie, Melin, Beatrice, von Wachenfeldt, Anna, Hogervorst, Frans B L, Verheus, Martijn

    Veröffentlicht in PloS one

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    Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers o... von Osorio, A, Milne, R L, Simard, J, Chenevix-Trench, G, Spurdle, A B, Beesley, J, Chen, X, Neuhausen, S L, Ding, Y C, Lindor, N, Manoukian, S, Barile, M, Tizzoni, L, Szabo, C I, Foretova, L, Claes, K, Greene, M H, Mai, P, Lejbkowicz, F, Andrulis, I L, Gerdes, A-M, Cruger, D G, Caligo, M A, Kaufman, B, Cohen, S, Gershoni-Baruch, R, Dagan, E, Jernström, H, Askmalm, M S, Arver, B, Malmer, B, Domchek, S M, Nathanson, K L, Brunet, J, Ramón y Cajal, T, Yannoukakos, D, Hamann, U, Verhoef, S, García, EB Gómez, Wijnen, J T, van den Ouweland, A, Easton, D F, Peock, S, Cook, M, Frost, D, Luccarini, C, Evans, D G, Lalloo, F, Eeles, R, Pichert, G, Cook, J, Hodgson, S, Morrison, P J, Douglas, F, Sinilnikova, O M, Barjhoux, L, Cassini, C, Révillion, F, Peyrat, J-P, Muller, D, Fricker, J-P, Lynch, H T, John, E M, Buys, S, Daly, M, Hopper, J L, Terry, M B, Goldgar, D, Singer, C F, Pfeiler, G, Hansen, Thomas v O, Johannsson, O T, Kirchhoff, T, Offit, K, Kosarin, K, Piedmonte, M, Wakeley, K, Boggess, J F, Basil, J, Blank, S V, Toland, A E, Imyanitov, E N, Schmutzler, R K, Engel, C, Meindl, A, Ditsch, N, Arnold, N, Niederacher, D, Deißler, H, Fiebig, B, Varon-Mateeva, R, Schaefer, D, Froster, U G, Caldes, T, de la Hoya, M, McGuffog, L, Antoniou, A C, Nevanlinna, H, Radice, P, Benítez, J

    Veröffentlicht in British journal of cancer

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