Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry von Toporowska, Joanna, Kapoor, Parth, Musgaard, Maria, Gherbi, Karolina, Sengmany, Kathy, Qu, Feng, Soave, Mark, Yen, Hsin-Yung, Hansen, Kjetil, Jazayeri, Ali, Hopper, Jonathan T. S., Politis, Argyris

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Metabotropic glutamate receptor 5 (mGlu5)‐positive allosteric modulators differentially induce or potentiate desensitization of mGlu5 signaling in recombinant cells and neurons von Hellyer, Shane D., Albold, Sabine, Sengmany, Kathy, Singh, Junaid, Leach, Katie, Gregory, Karen J.

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Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery von Sengmany, Kathy, Singh, Junaid, Stewart, Gregory D., Conn, P. Jeffrey, Christopoulos, Arthur, Gregory, Karen J.

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Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding site von Hellyer, Shane D., Sengmany, Kathy, Keller, Andrew N., Christopoulos, Arthur, Leach, Katie, Gregory, Karen J.

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Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism von Sengmany, Kathy, Hellyer, Shane D., Christopoulos, Arthur, Lapinsky, David J., Leach, Katie, Gregory, Karen J.

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Metabotropic glutamate receptor 5 (mGlu 5 )-positive allosteric modulators differentially induce or potentiate desensitization of mGlu 5 signaling in recombinant cells and neurons von Hellyer, Shane D, Albold, Sabine, Sengmany, Kathy, Singh, Junaid, Leach, Katie, Gregory, Karen J

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Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology von Sengmany, Kathy, Hellyer, Shane D., Albold, Sabine, Wang, Taide, Conn, P. Jeffrey, May, Lauren T., Christopoulos, Arthur, Leach, Katie, Gregory, Karen J.

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Allosteric Ligands of Metabotropic Glutamate Receptor 5 Have Biased Agonism and Cooperativity von Gregory, Karen, Sengmany, Kathy, Singh, Junaidjit, Christopoulos, Arthur

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Drugs to Tune Up Glutamatergic Systems: Modulators of Glutamate Metabotropic Receptors von Sengmany, Kathy, Gregory, Karen J.

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