Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery von Stock, Kristin, Estrada, Marta F., Vidic, Suzana, Gjerde, Kjersti, Rudisch, Albin, Santo, Vítor E., Barbier, Michaël, Blom, Sami, Arundkar, Sharath C., Selvam, Irwin, Osswald, Annika, Stein, Yan, Gruenewald, Sylvia, Brito, Catarina, van Weerden, Wytske, Rotter, Varda, Boghaert, Erwin, Oren, Moshe, Sommergruber, Wolfgang, Chong, Yolanda, de Hoogt, Ronald, Graeser, Ralph

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Structure–Activity Relationships of cyclo(l‑Tyrosyl‑l‑tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct... von Rajput, Sunnia, McLean, Kirsty J, Poddar, Harshwardhan, Selvam, Irwin R, Nagalingam, Gayathri, Triccas, James A, Levy, Colin W, Munro, Andrew W, Hutton, Craig A

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A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening app... von Frederickson, Martyn, Selvam, Irwin R., Evangelopoulos, Dimitrios, McLean, Kirsty J., Katariya, Mona M., Tunnicliffe, Richard B., Campbell, Bethany, Kavanagh, Madeline E., Charoensutthivarakul, Sitthivut, Blankley, Richard T., Levy, Colin W., de Carvalho, Luiz Pedro S., Leys, David, Munro, Andrew W., Coyne, Anthony G., Abell, Chris

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Addressing Antimicrobial Resistance in Mycobacterium tuberculosis - A Structure-Guided Campaign Against Cytochrome P450s CYP121A1, CYP141A1 and CYP143A1 von Selvam, Irwin

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The non‐swapped monomeric structure of the arginine‐binding protein from Thermotoga maritima von Smaldone, Giovanni, Ruggiero, Alessia, Balasco, Nicole, Abuhammad, Areej, Autiero, Ida, Caruso, Daniela, Esposito, Davide, Ferraro, Giarita, Gelardi, Edoardo L. M., Moreira, Miguel, Quareshy, Mussa, Romano, Maria, Saaret, Annica, Selvam, Irwin, Squeglia, Flavia, Troisi, Romualdo, Kroon-Batenburg, Loes M. J., Esposito, Luciana, Berisio, Rita, Vitagliano, Luigi

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A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening app... von Frederickson, Martyn, Selvam, Irwin R, Evangelopoulos, Dimitrios, McLean, Kirsty J, Katariya, Mona M, Tunnicliffe, Richard B, Campbell, Bethany, Kavanagh, Madeline E, Charoensutthivarakul, Sitthivut, Blankley, Richard T, Levy, Colin W, de Carvalho, Luiz Pedro S, Leys, David, Munro, Andrew W, Coyne, Anthony G, Abell, Chris

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A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening app... von Frederickson, Martyn, Selvam, Irwin R, Evangelopoulos, Dimitrios, McLean, Kirsty J, Katariya, Mona M, Tunnicliffe, Richard B, Campbell, Bethany, Kavanagh, Madeline E, Charoensutthivarakul, Sitthivut, Blankley, Richard T, Levy, Colin W, de Carvalho, Luiz Pedro S, Leys, David, Munro, Andrew W, Coyne, Anthony G, Abell, Chris

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von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient‐derived endothelial colony‐forming cells von Bowman, Mackenzie, Casey, Lara, Selvam, Soundarya N., Lima, Patricia D. A., Rawley, Orla, Hinds, Megan, Tuttle, Angie, Grabell, Julie, Iorio, Alfonso, Walker, Irwin, Lillicrap, David, James, Paula

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