Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes von Majithia, Amit R., Flannick, Jason, Shahinian, Peter, Guo, Michael, Bray, Mark-Anthony, Fontanillas, Pierre, Gabriel, Stacey B., Rosen, Evan D., Altshuler, David

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Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice von Kurtzwald-Josefson, E., Hochhauser, H. E., Hrun-Khun, H. R. S., Bogachenko, B. K., Seidman, J. G. S., Aravot, A. D., Eldar, E. M., Shainberg, S. A., Arad, A. M.

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Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy von Ho, Carolyn Y, López, Begoña, Coelho-Filho, Otavio R, Lakdawala, Neal K, Cirino, Allison L, Jarolim, Petr, Kwong, Raymond, González, Arantxa, Colan, Steven D, Seidman, J.G, Seidman, Christine E, Díez, Javier

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Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis von Delgado-Olguín, Paul, Huang, Yu, Li, Xue, Christodoulou, Danos, Seidman, Christine E, Seidman, J G, Tarakhovsky, Alexander, Bruneau, Benoit G

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Glycogen Storage Diseases Presenting as Hypertrophic Cardiomyopathy von Arad, Michael, Maron, Barry J, Gorham, Joshua M, Johnson, Walter H, Saul, J. Philip, Perez-Atayde, Antonio R, Spirito, Paolo, Wright, Gregory B, Kanter, Ronald J, Seidman, J.G, Seidman, Christine E

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Identifying Sarcomere Gene Mutations in Hypertrophic Cardiomyopathy: A Personal History von Seidman, Christine E, Seidman, J.G

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Shared Genetic Causes of Cardiac Hypertrophy in Children and Adults von Morita, Hiroyuki, Rehm, Heidi L, Menesses, Andres, McDonough, Barbara, Roberts, Amy E, Kucherlapati, Raju, Towbin, Jeffrey A, Seidman, J.G, Seidman, Christine E

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Missense Mutations in the Rod Domain of the Lamin A/C Gene as Causes of Dilated Cardiomyopathy and Conduction-System Disease von Fatkin, Diane, MacRae, Calum, Sasaki, Takeshi, Wolff, Matthew R, Porcu, Maurizio, Frenneaux, Michael, Atherton, John, Vidaillet, Humberto J, Spudich, Serena, De Girolami, Umberto, Seidman, Christine E, Seidman, J.G, Muntoni, Francesco, Müehle, Gerry, Johnson, Wendy, McDonough, Barbara

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Dilated Cardiomyopathy and Heart Failure Caused by a Mutation in Phospholamban von Schmitt, Joachim P., Kamisago, Mitsuhiro, Asahi, Michio, Li, Guo Hua, Ahmad, Ferhaan, Mende, Ulrike, Kranias, Evangelia G., MacLennan, David H., Seidman, J. G., Seidman, Christine E.

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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice von Green, Eric M., Wakimoto, Hiroko, Anderson, Robert L., Evanchik, Marc J., Gorham, Joshua M., Harrison, Brooke C., Henze, Marcus, Kawas, Raja, Oslob, Johan D., Rodriguez, Hector M., Song, Yonghong, Wan, William, Leinwand, Leslie A., Spudich, James A., McDowell, Robert S., Seidman, J. G., Seidman, Christine E.

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Single-Cell Resolution of Temporal Gene Expression during Heart Development von DeLaughter, Daniel M., Bick, Alexander G., Wakimoto, Hiroko, McKean, David, Gorham, Joshua M., Kathiriya, Irfan S., Hinson, John T., Homsy, Jason, Gray, Jesse, Pu, William, Bruneau, Benoit G., Seidman, J.G., Seidman, Christine E.

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Spectrum of somatic mitochondrial mutations in five cancers von Larman, Tatianna C, DePalma, Steven R, Hadjipanayis, Angela G, Protopopov, Alexei, Zhang, Jianhua, Gabriel, Stacey B, Chin, Lynda, Seidman, Christine E, Kucherlapati, Raju, Seidman, J. G

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Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy von Hinson, John T., Chopra, Anant, Nafissi, Navid, Polacheck, William J., Benson, Craig C., Swist, Sandra, Gorham, Joshua, Yang, Luhan, Schafer, Sebastian, Sheng, Calvin C., Haghighi, Alireza, Homsy, Jason, Hubner, Norbert, Church, George, Cook, Stuart A., Linke, Wolfgang A., Chen, Christopher S., Seidman, J. G., Seidman, Christine E.

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Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes von Flannick, Jason, Beer, Nicola L, Bick, Alexander G, Agarwala, Vineeta, Molnes, Janne, Gupta, Namrata, Burtt, Noël P, Florez, Jose C, Meigs, James B, Taylor, Herman, Lyssenko, Valeriya, Irgens, Henrik, Fox, Ervin, Burslem, Frank, Johansson, Stefan, Brosnan, M Julia, Trimmer, Jeff K, Newton-Cheh, Christopher, Tuomi, Tiinamaija, Molven, Anders, Wilson, James G, O'Donnell, Christopher J, Kathiresan, Sekar, Hirschhorn, Joel N, Njølstad, Pål R, Rolph, Tim, Seidman, J G, Gabriel, Stacey, Cox, David R, Seidman, Christine E, Groop, Leif, Altshuler, David

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AMP-Activated Protein Kinase in the Heart: Role During Health and Disease von Arad, Michael, Seidman, Christine E, Seidman, J G

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Paternal-age-related de novo mutations and risk for five disorders von Taylor, Jacob L., Debost, Jean-Christophe P. G., Morton, Sarah U., Wigdor, Emilie M., Heyne, Henrike O., Lal, Dennis, Howrigan, Daniel P., Bloemendal, Alex, Larsen, Janne T., Kosmicki, Jack A., Weiner, Daniel J., Homsy, Jason, Seidman, Jonathan G., Seidman, Christine E., Agerbo, Esben, McGrath, John J., Mortensen, Preben Bo, Petersen, Liselotte, Daly, Mark J., Robinson, Elise B.

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Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly von NIIMURA, Hideshi, PATTON, Kristen K, MCKENNA, William J, SOULTS, Johann, MARON, Barry J, SEIDMAN, J. G, SEIDMAN, Christine E

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poly(UG)-tailed RNAs in genome protection and epigenetic inheritance von Shukla, Aditi, Yan, Jenny, Pagano, Daniel J., Dodson, Anne E., Fei, Yuhan, Gorham, Josh, Seidman, J. G., Wickens, Marvin, Kennedy, Scott

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A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy von Davis, Jennifer, Davis, L. Craig, Correll, Robert N., Makarewich, Catherine A., Schwanekamp, Jennifer A., Moussavi-Harami, Farid, Wang, Dan, York, Allen J., Wu, Haodi, Houser, Steven R., Seidman, Christine E., Seidman, Jonathan G., Regnier, Michael, Metzger, Joseph M., Wu, Joseph C., Molkentin, Jeffery D.

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Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy von Goli, Rahul, Li, Jian, Brandimarto, Jeff, Levine, Lisa D., Riis, Valerie, McAfee, Quentin, DePalma, Steven, Haghighi, Alireza, Seidman, J. G., Seidman, Christine E., Jacoby, Daniel, Macones, George, Judge, Daniel P., Rana, Sarosh, Margulies, Kenneth B., Cappola, Thomas P., Alharethi, Rami, Damp, Julie, Hsich, Eileen, Elkayam, Uri, Sheppard, Richard, Alexis, Jeffrey D., Boehmer, John, Kamiya, Chizuko, Gustafsson, Finn, Damm, Peter, Ersbøll, Anne S., Goland, Sorel, Hilfiker-Kleiner, Denise, McNamara, Dennis M., Arany, Zolt

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