Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group von Mandelker, D., Donoghue, M., Talukdar, S., Bandlamudi, C., Srinivasan, P., Vivek, M., Jezdic, S., Hanson, H., Snape, K., Kulkarni, A., Hawkes, L., Douillard, J.-Y, Wallace, S.E., Rial-Sebbag, E., Meric-Bersntam, F., George, A., Chubb, D., Loveday, C., Ladanyi, M., Berger, M.F., Taylor, B.S., Turnbull, C.

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Trends in ethical and legal frameworks for the use of human biobanks von Cambon-Thomsen, A, Rial-Sebbag, E, Knoppers, B. M

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Erratum to ‘Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group’: [Annals of Oncology 30 (2019) 1221–1231] von Mandelker, D., Donoghue, M., Talukdar, S., Bandlamudi, C., Srinivasan, P., Vivek, M., Jezdic, S., Hanson, H., Snape, K., Kulkarni, A., Hawkes, L., Douillard, J.-Y., Wallace, S.E., Rial-Sebbag, E., Meric-Bersntam, F., George, A., Chubb, D., Loveday, C., Ladanyi, M., Berger, M.F., Taylor, B.S., Turnbull, C.

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The humanitarian and outreach ethics charter in ENT. Ethics at the heart of missions von Mom, T., Gardini, B., Rial-Sebbag, E., Fraysse, B.

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Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape von Kalokairinou, L., Howard, H. C., Slokenberga, S., Fisher, E., Flatscher-Thöni, M., Hartlev, M., van Hellemondt, R., Juškevičius, J., Kapelenska-Pregowska, J., Kováč, P., Lovrečić, L., Nys, H., de Paor, A., Phillips, A., Prudil, L., Rial-Sebbag, E., Romeo Casabona, C. M., Sándor, J., Schuster, A., Soini, S., Søvig, K. H., Stoffel, D., Titma, T., Trokanas, T., Borry, P.

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Accreditation and regulations in cell therapy von Chabannon, C., Caunday-Rigot, O., Faucher, C., Slaper-Cortenbach, I., Calmels, B., Lemarie, C., Mahalatchimy, A., McGrath, E., Rial-Sebbag, E.

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One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans von Howard, Heidi C, van El, Carla G, Forzano, Francesca, Radojkovic, Dragica, Rial-Sebbag, Emmanuelle, de Wert, Guido, Borry, Pascal, Cornel, Martina C

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2179P Prospective monitoring of autoimmune events in cancer immunotherapy patients: A report on the first 658 patients in the PRAISE study von Sebbag, E., Cloarec, N., Monnet, I., Najem, A., Rajpar, S.L., San, T., Porneuf, M., Barthelemy, P., Rizzo, C., Meunier, J., Hamamouche, N., Servy, H., Desjeux, G., Arnold, C., Sauleau, E-A., Chouaid, C., Sedmak, N., Gottenberg, J-E.

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Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study von van der Wouden, Cathelijne H., Bohringer, Stefan, Cecchin, Erika, Cheung, Ka-Chun, Lucia Davila-Fajardo, Cristina, Deneer, Vera H. M., Dolzan, Vita, Ingelman-Sundberg, Magnus, Jonsson, Siv, Karlsson, Mats, Kriek, Marjolein, Mitropoulou, Christina, Patrinos, George P., Pirmohamed, Munir, Rial-Sebbag, Emmanuelle, Samwald, Matthias, Schwab, Matthias, Steinberger, Daniela, Stingl, Julia, Sunder-Plassmann, Gere, Toffoli, Giuseppe, Turner, Richard M., van Rhenen, Mandy H., van Zwet, Erik, Swen, Jesse J., Guchelaar, Henk-Jan

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European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death von Fellmann, Florence, van El, Carla G, Charron, Philippe, Michaud, Katarzyna, Howard, Heidi C, Boers, Sarah N, Clarke, Angus J, Duguet, Anne-Marie, Forzano, Francesca, Kauferstein, Silke, Kayserili, Hülya, Lucassen, Anneke, Mendes, Álvaro, Patch, Christine, Radojkovic, Dragica, Rial-Sebbag, Emmanuelle, Sheppard, Mary N, Tassé, Anne-Marie, Temel, Sehime G, Sajantila, Antti, Basso, Cristina, Wilde, Arthur A M, Cornel, Martina C

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Toward a common language for biobanking von Fransson, Martin N, Rial-Sebbag, Emmanuelle, Brochhausen, Mathias, Litton, Jan-Eric

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Pharmacogenomics decision support in the U-PGx project: Results and advice from clinical implementation across seven European countries von Blagec, Kathrin, Swen, Jesse J, Koopmann, Rudolf, Cheung, Ka-Chun, Crommentuijn-van Rhenen, Mandy, Holsappel, Inge, Konta, Lidija, Ott, Simon, Steinberger, Daniela, Xu, Hong, Cecchin, Erika, Dolžan, Vita, Dávila-Fajardo, Cristina Lucía, Patrinos, George P, Sunder-Plassmann, Gere, Turner, Richard M, Pirmohamed, Munir, Guchelaar, Henk-Jan, Samwald, Matthias

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2182P Patient involvement to improve prospective follow-up: Quality of life data after cancer immunotherapy from the PRAISE study von Sebbag, E., Gottenberg, J-E., Chouaid, C., Cloarec, N., Najem, A., Rajpar, S.L., San, T., Porneuf, M., Barthelemy, P., Rizzo, C., Chauvenet, L., Meunier, J., Jouve, A. Darut, Falkowski, S., Paitel, J-F., Geoffrois, L., Oudard, S., Braithwaite, B., Hamamouche, N., Servy, H.

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Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE von De Wert, Guido, Heindryckx, Björn, Pennings, Guido, Clarke, Angus, Eichenlaub-Ritter, Ursula, van El, Carla G, Forzano, Francesca, Goddijn, Mariëtte, Howard, Heidi C, Radojkovic, Dragica, Rial-Sebbag, Emmanuelle, Dondorp, Wybo, Tarlatzis, Basil C, Cornel, Martina C

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Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group (vol 30, pg 1221, 2019) von Mandelker, D., Donoghue, M., Talukdar, S., Bandlamudi, C., Srinivasan, P., Vivek, M., Jezdic, S., Hanson, H., Snape, K., Kulkarni, A., Hawkes, L., Douillard, J. -Y., Wallace, S. E., Rial-Sebbag, E., Meric-Bersntam, F., George, A., Chubb, D., Loveday, C., Ladanyi, M., Berger, M. F., Taylor, B. S., Turnbull, C.

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Erratum to ‘Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group’: Annals of Oncology 30 (2019) 1221–1231 von Mandelker, D., Donoghue, M., Talukdar, S., Bandlamudi, C., Srinivasan, P., Vivek, M., Jezdic, S., Hanson, H., Snape, K., Kulkarni, A., Hawkes, L., Douillard, J.-Y., Wallace, S.E., Rial-Sebbag, E., Meric-Bersntam, F., George, A., Chubb, D., Loveday, C., Ladanyi, M., Berger, M.F., Taylor, B.S., Turnbull, C.

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Optimisation de la prise en charge de l’ostéoporose après repérage des patients traités par vertébroplastie non néoplasique : expérience strasbourgeoise Parcours Os von Javier, R.M., Sebbag, E., Bastian, I., Garnon, J., Gangi, A.

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MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine von Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon‐Thomsen, A., Keil, T., Haahtela, T., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi‐Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev‐Jensen, C., Brunekreef, B., Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Forastiere, F., Garcia‐Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Kowalski, M. L., Lau, S., Lodrup‐Carlsen, K. C., Lopez‐Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial‐Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., van Cauwenberge, P., van Oosterhout, A. J. M., Varraso, R., von Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J., Zuberbier, T.

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Épidémiologie de l’incidence des fractures chez les patients traités par dénosumab : données sur 271 295 patients issues du système national d’information de santé français... von Laurent, D., Yamdjieu Ngadeu, C., Javier, R.M., Confavreux, C., Gottenberg, J.E., Sebbag, E.

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Blinatumomab : un anti-CD3/CD19 en alternative aux CAR-T cell dans la sclérodermie systémique ? von Scherlinger, M., Chatelus, E., Sebbag, E., Martin, T., Simand, C., El Aatmani, A., Gottenberg, J.E., Sibilia, J.

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