Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B von Collins, Ian, Caldwell, John, Fonseca, Tatiana, Donald, Alastair, Bavetsias, Vassilios, Hunter, Lisa-Jane K., Garrett, Michelle D., Rowlands, Martin G., Aherne, G. Wynne, Davies, Thomas G., Berdini, Valerio, Woodhead, Steven J., Davis, Deborah, Seavers, Lisa C.A., Wyatt, Paul G., Workman, Paul, McDonald, Edward

Volltext

Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors von Howard, Nigel, Abell, Chris, Blakemore, Wendy, Chessari, Gianni, Congreve, Miles, Howard, Steven, Jhoti, Harren, Murray, Christopher W, Seavers, Lisa C. A, van Montfort, Rob L. M

Volltext

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation von Gill, Adrian L, Frederickson, Martyn, Cleasby, Anne, Woodhead, Steven J, Carr, Maria G, Woodhead, Andrew J, Walker, Margaret T, Congreve, Miles S, Devine, Lindsay A, Tisi, Dominic, O'Reilly, Marc, Seavers, Lisa C. A, Davis, Deborah J, Curry, Jayne, Anthony, Rachel, Padova, Alessandro, Murray, Christopher W, Carr, Robin A. E, Jhoti, Harren

Volltext