In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase von CHUNG-FAYE, G. A, CHEN, M. J, GREEN, N. K, BURTON, A, ANDERSON, D, MAUTNER, V, SEARLE, P. F, KERR, D. J

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Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer : Construction and testing of a tissue-specific adenovirus vector von LATHAM, J. P. F, SEARLE, P. F, MAUTNER, V, JAMES, N. D

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Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle von GUISE, C. P, GROVE, J. I, HYDE, E. I, SEARLE, P. F

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Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector von CHEN, M-J, GREEN, N. K, REYNOLDS, G. M, FLAVELL, J. R, MAUTNER, V, KERR, D. J, YOUNG, L. S, SEARLE, P. F

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Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo von White, C L, Menghistu, T, Twigger, K R, Searle, P F, Bhide, S A, Vile, R G, Melcher, A A, Pandha, H S, Harrington, K J

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E. coli NfsA: an alternative nitroreductase for prodrug activation gene therapy in combination with CB1954 von Vass, S O, Jarrom, D, Wilson, W R, Hyde, E I, Searle, P F

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Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954 von MCNEISH, I. A, GREEN, N. K, GILLIGAN, M. G, FORD, M. J, MAUTNER, V, YOUNG, L. S, KERR, D. J, SEARLE, P. F

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Inhibition of NF-κB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy von PALMER, D. H, CHEN, M.-J, SEARLE, P. F, KERR, D. J, YOUNG, L. S

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Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector‐mediated expression of E. coli nitroreductase von Weedon, Sarah J., Green, Nicola K., McNeish, Iain A., Gilligan, Moira G., Mautner, Vivien, Wrighton, Christopher J., Mountain, Andrew, Young, Lawrence S., Kerr, David J., Searle, Peter F.

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Vectors based on reducible polycations facilitate intracellular release of nucleic acids von Read, Martin L., Bremner, K. Helen, Oupický, David, Green, Nicola K., Searle, Peter F., Seymour, Leonard W.

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Tumour-specific therapeutic adenovirus vectors : repression of transgene expression in healthy cells by endogenous p53 von LIPINSKI, K. S, DJEHA, A. H, KRAUSZ, E, LANE, D. P, SEARLE, P. F, MOUNTAIN, A, WRIGHTON, C. J

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Production of Retroviral Vectors for Gene Therapy with the Human Packaging Cell Line FLYRD18 von Gerin, Patrick A., Searle, Peter F., Al-Rubeai, Mohamed

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A 12-Base-Pair DNA Motif That is Repeated Several Times in Metallothionein Gene Promoters Confers Metal Regulation to a Heterologous Gene von Stuart, Gary W., Searle, Peter F., Chen, Howard Y., Brinster, Ralph L., Palmiter, Richard D.

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Building a metal-responsive promoter with synthetic regulatory elements von SEARLE, P. F, STUART, G. W, PALMITER, R. D

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Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences von Stuart, Gary W, Searle, Peter F, Palmiter, Richard D

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Improved titers of retroviral vectors from the human FLYRD18 packaging cell line in serum- and protein-free medium von GERIN, P. A, GILLIGAN, M. G, SEARLE, P. F, AL-RUBEAI, M

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Adenoviral vectors: not to be sneezed at von Searle, P F, Mautner, V

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Gene directed enzyme prodrug therapy for cancer von McNeish, I.A, Searle, P.F, Young, L.S, Kerr, D.J

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Regulation, linkage, and sequence of mouse metallothionein I and II genes von Searle, P F, Davison, B L, Stuart, G W, Wilkie, T M, Norstedt, G, Palmiter, R D

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Stomach Cancer in Transgenic Mice Expressing Human Papillomavirus Type 16 Early Region Genes From a Keratin Promoter von Searle, Peter F, Thomas, David P, Faulkner, Karen B, Tinsley, Jonathon M

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