Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity von Huang, Yaoxing, Yu, Jian, Lanzi, Anastasia, Yao, Xin, Andrews, Chasity D., Tsai, Lily, Gajjar, Mili R., Sun, Ming, Seaman, Michael S., Padte, Neal N., Ho, David D.

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Broad and potent neutralization of HIV-1 by human-llama fusion antibodies derived from immunized llamas von McCoy, LE, Rutten, L, Dekkers, G, Blanchetot, C, Strokappe, NM, Forsman-Quigley, A, Seaman, MS, de Haard, H, Verrips, T, Weiss, RA

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Comparison of the depth of vaccine-elicited HIV-1 Env epitope-specific CD8+ T lymphocyte responses von Hulot, SL, Korber, BT, Pantaleo, G, Tartaglia, J, Jacobs, B, Perdiguero, B, Gomez, CE, Esteban, M, Letvin, N, Seaman, MS, Haynes, B, Santra, S

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A method for identification of HIV gp140 binding memory B cells in human blood von Scheid, Johannes F., Mouquet, Hugo, Feldhahn, Niklas, Walker, Bruce D., Pereyra, Florencia, Cutrell, Emily, Seaman, Michael S., Mascola, John R., Wyatt, Richard T., Wardemann, Hedda, Nussenzweig, Michel C.

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Persistent Low-Level Viremia in HIV-1 Elite Controllers and Relationship to Immunologic Parameters von Pereyra, Florencia, Palmer, Sarah, Miura, Toshiyuki, Block, Brian L., Wiegand, Ann, Rothchild, Alissa C., Baker, Brett, Rosenberg, Rachel, Cutrell, Emily, Seaman, Michael S., Coffin, John M., Walker, Bruce D.

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First-in-human phase 1 trial of the safety and immunogenicity of a recombinant adenovirus serotype 5 HVR48 (rAd5HVR48) HIV-1 vaccine von Walsh, SR, Seaman, MS, Johnson, JA, Tucker, RP, Krause, KH, Weijtens, M, Pau, MG, Goudsmit, J, Dolin, R, Barouch, DH, Baden, LR

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Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants von Klein, Florian, Nogueira, Lilian, Nishimura, Yoshiaki, Phad, Ganesh, West, Jr, Anthony P, Halper-Stromberg, Ariel, Horwitz, Joshua A, Gazumyan, Anna, Liu, Cassie, Eisenreich, Thomas R, Lehmann, Clara, Fätkenheuer, Gerd, Williams, Constance, Shingai, Masashi, Martin, Malcolm A, Bjorkman, Pamela J, Seaman, Michael S, Zolla-Pazner, Susan, Karlsson Hedestam, Gunilla B, Nussenzweig, Michel C

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P04-55 LB. Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes von Zolla-Pazner, S, Wrin, T, Seaman, MS, Yu, X, Wood, B, Self, S, Hioe, CE

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P17-09. Immunization with a single HIV-1 envelope sequence can generate CD8+ T lymphocytes capable of recognizing multiple variant forms of envelope von Hulot, S L, Seaman, MS, Dorosh, LA, Korber, B T, Letvin, N L

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P04-10. Neutralization of Tier 1 and Tier 2 pseudoviruses by human anti-V3 monoclonal antibodies von Gorny, MK, Williams, C, O'Neal, T, Choudhary, AK, Luthra, K, Wood, B, Seaman, MS, Nyambi, P, Zolla-Pazner, S

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P04-09. Induction of cross-clade neutralizing antibodies with a prime/boost vaccine strategy focused on a neutralizing epitope von Zolla-Pazner, S, Kong, X, Cardozo, T, Hioe, C, Cohen, S, Jiang, X, Gorny, M K, Totrov, M, Pinter, A, Krachmarov, C, Seaman, MS, Wang, S, Lu, S

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Discovery of O-linked carbohydrate on HIV-1 envelope and its role in shielding against one category of broadly neutralizing antibodies von Silver, ZA, Antonopoulos, A, Haslam, SM, Dell, A, Dickinson, GM, Seaman, MS, Desrosiers, RC

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P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys von Yeh, WW, Rahman, I, Hraber, P, Giri, A, Nevidomskyte, D, Coffey, RT, Asmal, M, Miljkovic, S, Whitney, JB, Keele, BF, Shaw, GM, Korber, BT, Seaman, MS, Letvin, NL

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Replication-Defective Adenovirus Serotype 5 Vectors Elicit Durable Cellular and Humoral Immune Responses in Nonhuman Primates von SANTRA, Sampa, SEAMAN, Michael S, CHAKRABARTI, Bimal K, YUE HUANG, YANG, Zhi-Yong, MASCOLA, John R, NABEL, Gary J, LETVIN, Norman L, LING XU, BAROUCH, Dan H, LORD, Carol I, LIFTON, Michelle A, GORGONE, Darci A, BEAUDRY, Kristin R, SVEHLA, Krisha, WELCHER, Brent

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Pathogenicity of Simian-Human Immunodeficiency Virus SHIV-89.6P and SIVmac Is Attenuated in Cynomolgus Macaques and Associated with Early T-Lymphocyte Responses von REIMANN, Keith A, PARKER, Robert A, NABEL, Gary J, LETVIN, Norman L, SEAMAN, Michael S, BEAUDRY, Kristin, BEDDALL, Margaret, PETERSON, Lauren, WILLIAMS, Kenneth C, VEAZEY, Ronald S, MONTEFIORI, David C, MASCOLA, John R

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Multiclade Human Immunodeficiency Virus Type 1 Envelope Immunogens Elicit Broad Cellular and Humoral Immunity in Rhesus Monkeys von SEAMAN, Michael S, LING XU, KOUP, Richard A, MASCOLA, John R, NABEL, Gary J, LETVIN, Norman L, BEAUDRY, Kristin, MARTIN, Kristi L, BEDDALL, Margaret H, MIURA, Ayako, SAMBOR, Anna, CHAKRABARTI, Bimal K, YUE HUANG, BAILER, Robert

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Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines von Sumida, Shawn M, McKay, Paul F, Truitt, Diana M, Kishko, Michael G, Arthur, Janelle C, Seaman, Michael S, Jackson, Shawn S, Gorgone, Darci A, Lifton, Michelle A, Letvin, Norman L, Barouch, Dan H

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Heterologous Envelope Immunogens Contribute to AIDS Vaccine Protection in Rhesus Monkeys von LETVIN, Norman L, YUE HUANG, MIURA, Ayako, KONG, Wing-Pui, YANG, Zhi-Yong, GELMAN, Rebecca S, GOLUBEVA, Olga G, MONTEFIORI, David C, MASCOLA, John R, NABEL, Gary J, CHAKRABARTI, Bimal K, LING XU, SEAMAN, Michael S, BEAUDRY, Kristin, KORIOTH-SCHMITZ, Birgit, YU, Faye, ROHNE, Daniela, MARTIN, Kristi L

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Enhanced immunogenicity of an HIV-1 DNA vaccine delivered with electroporation via combined intramuscular and intradermal routes von Mann, JFS, Mckay, PF, Fiserova, A, Klein, K, Cope, A, Rogers, P, Swales, J, Seaman, MS, Combadiere, B, Shattock, RJ

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Characterization of a trimeric MPER containing HIV-1 gp41 antigen von Hinz, Andreas, Schoehn, Guy, Quendler, Heribert, Hulsik, David Lutje, Stiegler, Gabi, Katinger, Hermann, Seaman, Michael S, Montefiori, David, Weissenhorn, Winfried

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