Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins von Ali, Youssif M., Ferrari, Matteo, Lynch, Nicholas J., Yaseen, Sadam, Dudler, Thomas, Gragerov, Sasha, Demopulos, Gregory, Heeney, Jonathan L., Schwaeble, Wilhelm J.

Volltext

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection von Ali, Youssif M, Lynch, Nicholas J, Haleem, Kashif S, Fujita, Teizo, Endo, Yuichi, Hansen, Soren, Holmskov, Uffe, Takahashi, Kazue, Stahl, Gregory L, Dudler, Thomas, Girija, Umakhanth V, Wallis, Russell, Kadioglu, Aras, Stover, Cordula M, Andrew, Peter W, Schwaeble, Wilhelm J

Volltext

Paths reunited: Initiation of the classical and lectin pathways of complement activation von Wallis, Russell, Mitchell, Daniel A, Schmid, Ralf, Schwaeble, Wilhelm J, Keeble, Anthony H

Volltext

Mannan‐binding lectin‐associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4... von Asgari, Elham, Farrar, Conrad A., Lynch, Nicholas, Ali, Youssif M., Roscher, Silke, Stover, Cordula, Zhou, Wuding, Schwaeble, Wilhelm J., Sacks, Steven H.

Volltext

Structure of the C1r–C1s interaction of the C1 complex of complement activation von Almitairi, Jamal O. M., Girija, Umakhanth Venkatraman, Furze, Christopher M., Simpson-Gray, Xanthe, Badakshi, Farah, Marshall, Jamie E., Schwaeble, Wilhelm J., Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell

Volltext

Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury von Farrar, Conrad A, Tran, David, Li, Ke, Wu, Weiju, Peng, Qi, Schwaeble, Wilhelm, Zhou, Wuding, Sacks, Steven H

Volltext

The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface von Haleem, Kashif S, Ali, Youssif M, Yesilkaya, Hasan, Kohler, Thomas, Hammerschmidt, Sven, Andrew, Peter W, Schwaeble, Wilhelm J, Lynch, Nicholas J

Volltext

The complement system in ischemia–reperfusion injuries von Gorsuch, William B, Chrysanthou, Elvina, Schwaeble, Wilhelm J, Stahl, Gregory L

Volltext

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury von Schwaeble, Wilhelm J, Lynch, Nicholas J, Clark, James E, Marber, Michael, Samani, Nilesh J, Ali, Youssif Mohammed, Dudler, Thomas, Parent, Brian, Lhotta, Karl, Wallis, Russell, Farrar, Conrad A, Sacks, Steven, Lee, Haekyung, Zhang, Ming, Iwaki, Daisuke, Takahashi, Minoru, Fujita, Teizo, Tedford, Clark E, Stover, Cordula M

Volltext

Lectin pathway effector enzyme mannan‐binding lectin‐associated serine protease‐2 can activate native complement C3 in absence of C4 and/or C2 von Yaseen, Sadam, Demopulos, Gregory, Dudler, Thomas, Yabuki, Munehisa, Wood, Christi L., Cummings, W. Jason, Tjoelker, Larry W., Fujita, Teizo, Sacks, Steven, Garred, Peter, Andrew, Peter, Sim, Robert B., Lachmann, Peter J., Wallis, Russell, Lynch, Nicholas, Schwaeble, Wilhelm J.

Volltext

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation von Girija, Umakhanth Venkatraman, Gingras, Alexandre R., Marshall, Jamie E., Panchal, Roshni, Sheikh, Md. Arif, Gál, Péter, Schwaeble, Wilhelm J., Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell

Volltext

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice von Ali, Youssif M, Lynch, Nicholas J, Shaaban, Ahmed A, Rizk, Dina E, Abdel-Rahman, Shaymaa H, Khatri, Priyanka, Yabuki, Munehisa, Yaseen, Sadam, Dudler, Thomas, Demopulos, Gregory, Schwaeble, Wilhelm J

Volltext

Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury von Alghadban, Samy, Kenawy, Hany I, Dudler, Thomas, Schwaeble, Wilhelm J, Brunskill, Nigel J

Volltext

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q von Nauta, Alma J., Bottazzi, Barbara, Mantovani, Alberto, Salvatori, Giovanni, Kishore, Uday, Schwaeble, Wilhelm J., Gingras, Alexandre R., Tzima, Sotiria, Vivanco, Fernando, Egido, Jesús, Tijsma, Odette, Hack, Erik C., Daha, Mohamed R., Roos, Anja

Volltext

Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot von Gulla, Krishana C, Gupta, Kshitij, Krarup, Anders, Gal, Peter, Schwaeble, Wilhelm J, Sim, Robert B, O'Connor, C. David, Hajela, Krishnan

Volltext

Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae von Ali, Youssif M, Kenawy, Hany I, Muhammad, Adnan, Sim, Robert B, Andrew, Peter W, Schwaeble, Wilhelm J

Volltext

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases? von Poppelaars, Felix, Faria, Bernardo, Schwaeble, Wilhelm, Daha, Mohamed R.

Volltext

Loss of Properdin Exacerbates C3 Glomerulopathy Resulting from Factor H Deficiency von RUSEVA, Marieta M, VERNON, Katherine A, LESHER, Allison M, SCHWAEBLE, Wilhelm J, ALI, Youssif M, BOTTO, Marina, COOK, Terence, WENCHAO SONG, STOVER, Cordula M, CALEB PICKERING, Matthew

Volltext

Properdin binds independent of complement activation in an in vivo model of anti–glomerular basement membrane disease von O’Flynn, Joseph, Kotimaa, Juha, Faber-Krol, Ria, Koekkoek, Karin, Klar-Mohamad, Ngaisah, Koudijs, Angela, Schwaeble, Wilhelm J., Stover, Cordula, Daha, Mohamed R., van Kooten, Cees

Volltext

The lectin pathway of complement activation contributes to protection from West Nile virus infection von Fuchs, Anja, Pinto, Amelia K, Schwaeble, Wilhelm J, Diamond, Michael S

Volltext