GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers von Mermel, Craig H, Schumacher, Steven E, Hill, Barbara, Meyerson, Matthew L, Beroukhim, Rameen, Getz, Gad

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β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis von Rosenbluh, Joseph, Nijhawan, Deepak, Cox, Andrew G., Li, Xingnan, Neal, James T., Schafer, Eric J., Zack, Travis I., Wang, Xiaoxing, Tsherniak, Aviad, Schinzel, Anna C., Shao, Diane D., Schumacher, Steven E., Weir, Barbara A., Vazquez, Francisca, Cowley, Glenn S., Root, David E., Mesirov, Jill P., Beroukhim, Rameen, Kuo, Calvin J., Goessling, Wolfram, Hahn, William C.

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Pan-cancer patterns of somatic copy number alteration von Zack, Travis I, Schumacher, Steven E, Carter, Scott L, Cherniack, Andrew D, Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S, Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H, Sougnez, Carrie, Gabriel, Stacey B, Hernandez, Bryan, Shen, Hui, Laird, Peter W, Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen

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Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy von Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Anderson, Kenneth C., Richardson, Paul, Krishnan, Amrita, Lonial, Sagar, Kaufman, Jonathan, Siegel, David S., Vesole, David H., Roy, Vivek, Rivera, Candido E., Rajkumar, S. Vincent, Kumar, Shaji, Fonseca, Rafael, Ahmann, Greg J., Bergsagel, P. Leif, Stewart, A. Keith, Hofmeister, Craig C., Efebera, Yvonne A., Jagannath, Sundar, Chari, Ajai, Trudel, Suzanne, Reece, Donna, Wolf, Jeffrey, Martin, Thomas, Zimmerman, Todd, Rosenbaum, Cara, Jakubowiak, Andrzej J., Lebovic, Daniel, Vij, Ravi, Stockerl-Goldstein, Keith, Getz, Gad, Golub, Todd R.

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Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition von Wong, Gabrielle S., Zhou, Jin, Liu, Jie Bin, Wu, Zhong, Xu, Xinsen, Li, Tianxia, Xu, David, Schumacher, Steven E., Puschhof, Jens, McFarland, James, Zou, Charles, Dulak, Austin, Henderson, Les, Xu, Peng, O’Day, Emily, Rendak, Rachel, Liao, Wei-li, Cecchi, Fabiola, Hembrough, Todd, Schwartz, Sarit, Szeto, Christopher, Rustgi, Anil K., Wong, Kwok-Kin, Diehl, J. Alan, Jensen, Karin, Graziano, Francesco, Ruzzo, Annamaria, Fereshetian, Shaunt, Mertins, Philipp, Carr, Steven A., Beroukhim, Rameen, Nakamura, Kenichi, Oki, Eiji, Watanabe, Masayuki, Baba, Hideo, Imamura, Yu, Catenacci, Daniel, Bass, Adam J.

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Cancer Vulnerabilities Unveiled by Genomic Loss von Nijhawan, Deepak, Zack, Travis I., Ren, Yin, Strickland, Matthew R., Lamothe, Rebecca, Schumacher, Steven E., Tsherniak, Aviad, Besche, Henrike C., Rosenbluh, Joseph, Shehata, Shyemaa, Cowley, Glenn S., Weir, Barbara A., Goldberg, Alfred L., Mesirov, Jill P., Root, David E., Bhatia, Sangeeta N., Beroukhim, Rameen, Hahn, William C.

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Landscape of Genomic Alterations in Pituitary Adenomas von Bi, Wenya Linda, Horowitz, Peleg, Greenwald, Noah F, Abedalthagafi, Malak, Agarwalla, Pankaj K, Gibson, Wiliam J, Mei, Yu, Schumacher, Steven E, Ben-David, Uri, Chevalier, Aaron, Carter, Scott, Tiao, Grace, Brastianos, Priscilla K, Ligon, Azra H, Ducar, Matthew, MacConaill, Laura, Laws, Jr, Edward R, Santagata, Sandro, Beroukhim, Rameen, Dunn, Ian F

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Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and Oncogenesis von DULAK, Austin M, SCHUMACHER, Steven E, TABERNERO, Josep, BARRETINA, Jordi, ENZINGER, Peter C, CORSO, Giovanni, ROVIELLO, Franco, LIN LIN, BANDLA, Santhoshi, LUKETICH, James D, PENNATHUR, Arjun, MEYERSON, Matthew, LIESHOUT, Jasper Van, OGINO, Shuji, SHIVDASANI, Ramesh A, BEER, David G, GODFREY, Tony E, BEROUKHIM, Rameen, BASS, Adam J, IMAMURA, Yu, FOX, Cameron, SHIM, Byoungyong, RAMOS, Alex H, SAKSENA, Gordon, BACA, Sylvan C, BASELGA, Jose

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Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients von Schumacher, Steven E, Shim, Byoung Yong, Corso, Giovanni, Ryu, Min-Hee, Kang, Yoon-Koo, Roviello, Franco, Saksena, Gordon, Peng, Shouyong, Shivdasani, Ramesh A, Bass, Adam J, Beroukhim, Rameen

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Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background von Elvers, Ingegerd, Turner-Maier, Jason, Swofford, Ross, Koltookian, Michele, Johnson, Jeremy, Stewart, Chip, Zhang, Cheng-Zhong, Schumacher, Steven E, Beroukhim, Rameen, Rosenberg, Mara, Thomas, Rachael, Mauceli, Evan, Getz, Gad, Palma, Federica Di, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin, Alföldi, Jessica

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ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens von Shao, Diane D, Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A, Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E, Zack, Travis I, Beroukhim, Rameen, Garraway, Levi A, Margolin, Adam A, Root, David E, Hahn, William C, Mesirov, Jill P

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Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis von Gong, Yongxing, Schumacher, Steven E, Wu, Wei H, Tang, Fanying, Beroukhim, Rameen, Chan, Timothy A

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Genomic landscape of high-grade meningiomas von Bi, Wenya Linda, Greenwald, Noah F., Abedalthagafi, Malak, Wala, Jeremiah, Gibson, Will J., Agarwalla, Pankaj K., Horowitz, Peleg, Schumacher, Steven E., Esaulova, Ekaterina, Mei, Yu, Chevalier, Aaron, A. Ducar, Matthew, Thorner, Aaron R., van Hummelen, Paul, O. Stemmer-Rachamimov, Anat, Artyomov, Maksym, Al-Mefty, Ossama, Dunn, Gavin P., Santagata, Sandro, Dunn, Ian F., Beroukhim, Rameen

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Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers von Hagerstrand, Daniel, Tong, Alexander, Schumacher, Steven E, Ilic, Nina, Shen, Rhine R, Cheung, Hiu Wing, Vazquez, Francisca, Shrestha, Yashaswi, Kim, So Young, Giacomelli, Andrew O, Rosenbluh, Joseph, Schinzel, Anna C, Spardy, Nicole A, Barbie, David A, Mermel, Craig H, Weir, Barbara A, Garraway, Levi A, Tamayo, Pablo, Mesirov, Jill P, Beroukhim, Rameen, Hahn, William C

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Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias von Dunford, Andrew, Weinstock, David M, Savova, Virginia, Schumacher, Steven E, Cleary, John P, Yoda, Akinori, Sullivan, Timothy J, Hess, Julian M, Gimelbrant, Alexander A, Beroukhim, Rameen, Lawrence, Michael S, Getz, Gad, Lane, Andrew A

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Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene von Shen, Chuan, Beroukhim, Rameen, Schumacher, Steven E, Zhou, Jing, Chang, Michelle, Signoretti, Sabina, Kaelin, Jr, William G

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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity von Dulak, Austin M, Stojanov, Petar, Peng, Shouyong, Lawrence, Michael S, Fox, Cameron, Stewart, Chip, Bandla, Santhoshi, Imamura, Yu, Schumacher, Steven E, Shefler, Erica, McKenna, Aaron, Carter, Scott L, Cibulskis, Kristian, Sivachenko, Andrey, Saksena, Gordon, Voet, Douglas, Ramos, Alex H, Auclair, Daniel, Thompson, Kristin, Sougnez, Carrie, Onofrio, Robert C, Guiducci, Candace, Beroukhim, Rameen, Zhou, Zhongren, Lin, Lin, Lin, Jules, Reddy, Rishindra, Chang, Andrew, Landrenau, Rodney, Pennathur, Arjun, Ogino, Shuji, Luketich, James D, Golub, Todd R, Gabriel, Stacey B, Lander, Eric S, Beer, David G, Godfrey, Tony E, Getz, Gad, Bass, Adam J

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Genomic evolution and chemoresistance in germ-cell tumours von Taylor-Weiner, Amaro, Zack, Travis, O’Donnell, Elizabeth, Guerriero, Jennifer L., Bernard, Brandon, Reddy, Anita, Han, G. Celine, AlDubayan, Saud, Amin-Mansour, Ali, Schumacher, Steven E., Litchfield, Kevin, Turnbull, Clare, Gabriel, Stacey, Beroukhim, Rameen, Getz, Gad, Carter, Scott L., Hirsch, Michelle S., Letai, Anthony, Sweeney, Christopher, Van Allen, Eliezer M

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MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism von Bandopadhayay, Pratiti, Ramkissoon, Lori A, Jain, Payal, Bergthold, Guillaume, Wala, Jeremiah, Zeid, Rhamy, Schumacher, Steven E, Urbanski, Laura, O'Rourke, Ryan, Gibson, William J, Pelton, Kristine, Ramkissoon, Shakti H, Han, Harry J, Zhu, Yuankun, Choudhari, Namrata, Silva, Amanda, Boucher, Katie, Henn, Rosemary E, Kang, Yun Jee, Knoff, David, Paolella, Brenton R, Gladden-Young, Adrianne, Varlet, Pascale, Pages, Melanie, Horowitz, Peleg M, Federation, Alexander, Malkin, Hayley, Tracy, Adam A, Seepo, Sara, Ducar, Matthew, Van Hummelen, Paul, Santi, Mariarita, Buccoliero, Anna Maria, Scagnet, Mirko, Bowers, Daniel C, Giannini, Caterina, Puget, Stephanie, Hawkins, Cynthia, Tabori, Uri, Klekner, Almos, Bognar, Laszlo, Burger, Peter C, Eberhart, Charles, Rodriguez, Fausto J, Hill, D Ashley, Mueller, Sabine, Haas-Kogan, Daphne A, Phillips, Joanna J, Santagata, Sandro, Stiles, Charles D, Bradner, James E, Jabado, Nada, Goren, Alon, Grill, Jacques, Ligon, Azra H, Goumnerova, Liliana, Waanders, Angela J, Storm, Phillip B, Kieran, Mark W, Ligon, Keith L, Beroukhim, Rameen, Resnick, Adam C

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BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma von BANDOPADHAYAY, Pratiti, BERGTHOLD, Guillaume, FURONG YU, NUJSAUBNUSI VUE, GIBSON, William J, PAOLELLA, Brenton R, MITRA, Siddhartha S, CHESHIER, Samuel H, JUN QI, LIU, Kun-Wei, WECHSLER-REYA, Robert, WEISS, William A, NGUYEN, Brian, SWARTLING, Fredrik J, KIERAN, Mark W, BRADNER, James E, BEROUKHIM, Rameen, CHO, Yoon-Jae, SCHUBERT, Simone, GHOLAMIN, Sharareh, YUJIE TANG, BOLIN, Sara, SCHUMACHER, Steven E, ZEID, Rhamy, MASOUD, Sabran

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