DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance von Ermolaeva, Maria A., Segref, Alexandra, Dakhovnik, Alexander, Ou, Hui-Ling, Schneider, Jennifer I., Utermöhlen, Olaf, Hoppe, Thorsten, Schumacher, Björn

Volltext

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors von Jachimowicz, Ron D., Beleggia, Filippo, Isensee, Jörg, Velpula, Bhagya Bhavana, Goergens, Jonas, Bustos, Matias A., Doll, Markus A., Shenoy, Anjana, Checa-Rodriguez, Cintia, Wiederstein, Janica Lea, Baranes-Bachar, Keren, Bartenhagen, Christoph, Hertwig, Falk, Teper, Nizan, Nishi, Tomohiko, Schmitt, Anna, Distelmaier, Felix, Lüdecke, Hermann-Josef, Albrecht, Beate, Krüger, Marcus, Schumacher, Björn, Geiger, Tamar, Hoon, Dave S.B., Huertas, Pablo, Fischer, Matthias, Hucho, Tim, Peifer, Martin, Ziv, Yael, Reinhardt, H. Christian, Wieczorek, Dagmar, Shiloh, Yosef

Volltext

The novel role of lymphatic vessels in the pathogenesis of ocular diseases von Clahsen, Thomas, Hadrian, Karina, Notara, Maria, Schlereth, Simona L., Howaldt, Antonia, Prokosch, Verena, Volatier, Thomas, Hos, Deniz, Schroedl, Falk, Kaser-Eichberger, Alexandra, Heindl, Ludwig M., Steven, Philipp, Bosch, Jacobus J., Steinkasserer, Alexander, Rokohl, Alexander C., Liu, Hanhan, Mestanoglu, Mert, Kashkar, Hamid, Schumacher, Björn, Kiefer, Friedemann, Schulte-Merker, Stefan, Matthaei, Mario, Hou, Yanhong, Fassbender, Sonja, Jantsch, Jonathan, Zhang, Wei, Enders, Philip, Bachmann, Björn, Bock, Felix, Cursiefen, Claus

Volltext

DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage von Mueller, Michael M., Castells-Roca, Laia, Babu, Vipin, Ermolaeva, Maria A., Müller, Roman-Ulrich, Frommolt, Peter, Williams, Ashley B., Greiss, Sebastian, Schneider, Jennifer I., Benzing, Thomas, Schermer, Bernhard, Schumacher, Björn

Volltext

The p53 network: cellular and systemic DNA damage responses in aging and cancer von Reinhardt, H. Christian, Schumacher, Björn

Volltext

DNA damage responses and p53 in the aging process von Ou, Hui-Ling, Schumacher, Björn

Volltext

DNA Damage Response and Immune Defense: Links and Mechanisms von Nakad, Rania, Schumacher, Björn

Volltext

DNA repair deficiencies and neurodegeneration von Ropert, Baptiste, Gallrein, Christian, Schumacher, Björn

Volltext

DNA repair mechanisms in cancer development and therapy von Torgovnick, Alessandro, Schumacher, Björn

Volltext

Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants von Wolters, Stefanie, Ermolaeva, Maria A, Bickel, Jeremy S, Fingerhut, Jaclyn M, Khanikar, Jayshree, Chan, Raymond C, Schumacher, Björn

Volltext

Molecular pathology of rare progeroid diseases von Rieckher, Matthias, Garinis, George A., Schumacher, Björn

Volltext

Insights from the worm: The C. elegans model for innate immunity von Ermolaeva, Maria A, Schumacher, Björn

Volltext

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis von Höpker, Katja, Hagmann, Henning, Khurshid, Safiya, Chen, Shuhua, Hasskamp, Pia, Seeger-Nukpezah, Tamina, Schilberg, Katharina, Heukamp, Lukas, Lamkemeyer, Tobias, Sos, Martin L, Thomas, Roman K, Lowery, Drew, Roels, Frederik, Fischer, Matthias, Liebau, Max C, Resch, Ulrike, Kisner, Tülay, Röther, Fabian, Bartram, Malte P, Müller, Roman Ulrich, Fabretti, Francesca, Kurschat, Peter, Schumacher, Björn, Gaestel, Matthias, Medema, René H, Yaffe, Michael B, Schermer, Bernhard, Reinhardt, H Christian, Benzing, Thomas

Volltext

Impact of genomic damage and ageing on stem cell function von Behrens, Axel, van Deursen, Jan M., Rudolph, K. Lenhard, Schumacher, Björn

Volltext

Delayed and accelerated aging share common longevity assurance mechanisms von Schumacher, Björn, van der Pluijm, Ingrid, Moorhouse, Michael J, Kosteas, Theodore, Robinson, Andria Rasile, Suh, Yousin, Breit, Timo M, van Steeg, Harry, Niedernhofer, Laura J, van Ijcken, Wilfred, Bartke, Andrzej, Spindler, Stephen R, Hoeijmakers, Jan H J, van der Horst, Gijsbertus T J, Garinis, George A

Volltext

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity von Garinis, George A., Uittenboogaard, Lieneke M., Stachelscheid, Heike, Fousteri, Maria, van Ijcken, Wilfred, Breit, Timo M., van Steeg, Harry, Mullenders, Leon H. F., van der Horst, Gijsbertus T. J., Brüning, Jens C., Niessen, Carien M., Hoeijmakers, Jan H. J., Schumacher, Björn

Volltext

Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner von Jokić, Mladen, Vlašić, Ignacija, Rinneburger, Miriam, Klümper, Niklas, Spiro, Judith, Vogel, Wenzel, Offermann, Anne, Kümpers, Christiane, Fritz, Christian, Schmitt, Anna, Riabinska, Arina, Wittersheim, Maike, Michels, Sebastian, Ozretić, Luka, Florin, Alexandra, Welcker, Daniela, Akyuz, Mehmet Deniz, Nowak, Michael, Erkel, Martin, Wolf, Jürgen, Büttner, Reinhard, Schumacher, Björn, Thomale, Jürgen, Persigehl, Thorsten, Maintz, David, Perner, Sven, Reinhardt, Hans Christian

Volltext

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity von Umansky, Carla, Morellato, Agustín E., Rieckher, Matthias, Scheidegger, Marco A., Martinefski, Manuela R., Fernández, Gabriela A., Pak, Oleg, Kolesnikova, Ksenia, Reingruber, Hernán, Bollini, Mariela, Crossan, Gerry P., Sommer, Natascha, Monge, María Eugenia, Schumacher, Björn, Pontel, Lucas B.

Volltext

Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy von Soltanmohammadi, Najmeh, Wang, Siyao, Schumacher, Björn

Volltext

Systemic DNA damage responses: organismal adaptations to genome instability von Ermolaeva, Maria A, Schumacher, Björn

Volltext