Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins von MARCU, M. G, SCHULTE, T. W, NECKERS, L

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The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin von SCHULTE, T. W, NECKERS, L. M

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Geldanamycin as a potential anti-cancer agent : Its molecular target and biochemical activity von NECKERS, L, SCHULTE, T. W, MIMNAUGH, E

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KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules von SOGA, S, NECKERS, L. M, AKINAGA, S, SCHULTE, T. W, SHIOTSU, Y, AKASAKA, K, NARUMI, H, AGATSUMA, T, IKUINA, Y, MURAKATA, C, TAMAOKI, T

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Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway von Schulte, Theodor W., Blagosklonny, Mikhail V., Romanova, Larissa, Mushinski, J. Frederic, Monia, Brett P., Johnston, Joseph F., Nguyen, Phuongmai, Trepel, Jane, Neckers, Leonard M.

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Stereospecific antitumor activity of radicicol oxime derivatives von SOGA, Shiro, SHARMA, Sreenath V, SCHULTE, Theodor W, NECKERS, Leonard M, AKINAGA, Shiro, SHIOTSU, Yukimasa, SHIMIZU, Makiko, TAHARA, Harunobu, YAMAGUCHI, Kazuo, IKUINA, Yoji, MURAKATA, Chikara, TAMAOKI, Tatsuya, KUREBAYASHI, Junichi

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Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association (∗) von Schulte, Theodor W., Blagosklonny, Mikhail V., Ingui, Christian, Neckers, Len

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The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation von Grenert, James P., Sullivan, William P., Fadden, Patrick, Haystead, Timothy A.J., Clark, Jenny, Mimnaugh, Edward, Krutzsch, Henry, Ochel, Hans-Joachim, Schulte, Theodor W., Sausville, Edward, Neckers, Leonard M., Toft, David O.

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Antibiotic Radicicol Binds to the N-Terminal Domain of Hsp90 and Shares Important Biologic Activities with Geldanamycin von Schulte, Theodor W., Akinaga, Shiro, Soga, Shiro, Sullivan, William, Stensgard, Bridget, Toft, David, Neckers, Leonard M.

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Taxol induction of p21WAF1 and p53 requires c-raf-1 von BLAGOSKLONNY, M. V, SCHULTE, T. W, PHYONGMAI NGUYEN, MIMNAUGH, E. G, TREPEL, J, NECKERS, L

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Geldanamycin-Induced Destabilization of Raf-1 Involves the Proteasome von Schulte, Theodor W., An, Won G., Neckers, Leonard M.

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Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destab... von Shiotsu, Y, Neckers, L M, Wortman, I, An, W G, Schulte, T W, Soga, S, Murakata, C, Tamaoki, T, Akinaga, S

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Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones von Schulte, T W, Akinaga, S, Murakata, T, Agatsuma, T, Sugimoto, S, Nakano, H, Lee, Y S, Simen, B B, Argon, Y, Felts, S, Toft, D O, Neckers, L M, Sharma, S V

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The Benzoquinone Ansamycin Geldanamycin Stimulates Proteolytic Degradation of Focal Adhesion Kinase von Ochel, Hans-Joachim, Schulte, Theodor W., Nguyen, Phuongmai, Trepel, Jane, Neckers, Len

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Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G1 phase accumulation against chronic myelogenous leukemia cells through destabil... von Shiotsu, Yukimasa, Neckers, Leonard M., Wortman, Ivo, An, Won G., Schulte, Theodor W., Soga, Shiro, Murakata, Chikara, Tamaoki, Tatsuya, Akinaga, Shiro

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Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint von KIM, Jung-Sik, PIRNIA, Farzaneh, MUSHINSKI, J. Frederic, TREPEL, Jane B, YUNG HYUN CHOI, NGUYEN, Phuongmai, KNEPPER, Benjamin, TSOKOS, Maria, SCHULTE, Theodor W, BIRRER, Michael J, BLAGOSKLONNY, Mikhail V, SCHAEFER, Olaf

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Hsp90 as an anti-cancer target von Neckers, Len, Mimnaugh, Edward, Schulte, Theodor W

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The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome von AN, W. G, SCHULTE, T. W, NECKERS, L. M

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Expression of PAX3 in Ewing's Sarcoma Family of Tumors von Schulte, Theodor W., Toretsky, Jeffrey A., Ress, Elisabeth, Helman, Lee, Neckers, Leonard M.

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Assessing the State-of-Practice of Model-Based Engineering in the Embedded Systems Domain von Liebel, Grischa, Marko, Nadja, Tichy, Matthias, Leitner, Andrea, Hansson, Jörgen

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