Electro-mechanical conditioning of human iPSC-derived cardiomyocytes for translational research von Kroll, Katharina, Chabria, Mamta, Wang, Ken, Häusermann, Fabian, Schuler, Franz, Polonchuk, Liudmila

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Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs von Jakubiak, Paulina, Reutlinger, Michael, Mattei, Patrizio, Schuler, Franz, Urtti, Arto, Alvarez-Sánchez, Rubén

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Are Biotransformation Studies of Therapeutic Proteins Needed? Scientific Considerations and Technical Challenges von Schadt, Simone, Hauri, Simon, Lopes, Filipe, Edelmann, Martin R., Staack, Roland F., Villaseñor, Roberto, Kettenberger, Hubert, Roth, Adrian B., Schuler, Franz, Richter, Wolfgang F., Funk, Christoph

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Minimizing the risk of chemically reactive metabolite formation of new drug candidates: implications for preclinical drug design von Brink, Andreas, Pähler, Axel, Funk, Christoph, Schuler, Franz, Schadt, Simone

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Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling von Kratochwil, Nicole A., Meille, Christophe, Fowler, Stephen, Klammers, Florian, Ekiciler, Aynur, Molitor, Birgit, Simon, Sandrine, Walter, Isabelle, McGinnis, Claudia, Walther, Johanna, Leonard, Brian, Triyatni, Miriam, Javanbakht, Hassan, Funk, Christoph, Schuler, Franz, Lavé, Thierry, Parrott, Neil J.

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A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides von Dieckmann, Andreas, Hagedorn, Peter H., Burki, Yvonne, Brügmann, Christine, Berrera, Marco, Ebeling, Martin, Singer, Thomas, Schuler, Franz

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Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip von Sasserath, Trevor, Rumsey, John W., McAleer, Christopher W., Bridges, Lee Richard, Long, Christopher J., Elbrecht, Daniel, Schuler, Franz, Roth, Adrian, Bertinetti‐LaPatki, Christina, Shuler, Michael L., Hickman, James J.

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Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs von Sewing, Sabine, Boess, Franziska, Moisan, Annie, Bertinetti-Lapatki, Cristina, Minz, Tanja, Hedtjaern, Maj, Tessier, Yann, Schuler, Franz, Singer, Thomas, Roth, Adrian B

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Discovery of Highly Selective Brain-Penetrant Vasopressin 1a Antagonists for the Potential Treatment of Autism via a Chemogenomic and Scaffold Hopping Approach von Ratni, Hasane, Rogers-Evans, Mark, Bissantz, Caterina, Grundschober, Christophe, Moreau, Jean-Luc, Schuler, Franz, Fischer, Holger, Alvarez Sanchez, Ruben, Schnider, Patrick

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Oxetanes as Promising Modules in Drug Discovery von Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Fischer, Holger, Wagner, Björn, Schuler, Franz, Polonchuk, Liudmila, Carreira, Erick M.

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Application of Imaging Techniques to Cases of Drug-Induced Crystal Nephropathy in Preclinical Studies von Lenz, Barbara, Brink, Andreas, Siam, Monira, De Paepe, Anne, Bassett, Simon, Eichinger-Chapelon, Anne, Maliver, Pierre, Neff, Rachel, Niederhauser, Urs, Steinhuber, Bernd, Zurbach, Raphael, Singer, Thomas, Funk, Christoph, Schuler, Franz, Albassam, Mudher, Schadt, Simone

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Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs von Haller, Stephanie, Schuler, Franz, Lazic, Stanley E., Bachir-Cherif, Dalila, Krämer, Stefanie D., Parrott, Neil J., Steiner, Guido, Belli, Sara

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Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling von Moisan, Annie, Gubler, Marcel, Zhang, Jitao David, Tessier, Yann, Dumong Erichsen, Kamille, Sewing, Sabine, Gérard, Régine, Avignon, Blandine, Huber, Sylwia, Benmansour, Fethallah, Chen, Xing, Villaseñor, Roberto, Braendli-Baiocco, Annamaria, Festag, Matthias, Maunz, Andreas, Singer, Thomas, Schuler, Franz, Roth, Adrian B.

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Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling von Schuler, Franz, Casida, John E

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Disrupting B and T-cell collaboration in autoimmune disease: T-cell engagers versus CAR T-cell therapy? von Shah, Kavina, Leandro, Maria, Cragg, Mark, Kollert, Florian, Schuler, Franz, Klein, Christian, Reddy, Venkat

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NADH-Quinone Oxidoreductase: PSST Subunit Couples Electron Transfer from Iron-Sulfur Cluster N2 to Quinone von Schuler, Franz, Yano, Takahiro, Di Bernardo, Salvatore, Yagi, Takao, Yankovskaya, Victoria, Singer, Thomas P., Casida, John E.

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Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats:... von Fischer, Holger, Senn, Claudia, Ullah, Mohammed, Cantrill, Carina, Schuler, Franz, Yu, Li

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The insecticide target in the PSST subunit of complex I von Schuler, Franz, Casida, John E

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Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats:... von Fischer, Holger, Senn, Claudia, Ullah, Mohammed, Cantrill, Carina, Schuler, Franz, Yu, Li

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Oxetanes in Drug Discovery: Structural and Synthetic Insights von Wuitschik, Georg, Carreira, Erick M, Wagner, Björn, Fischer, Holger, Parrilla, Isabelle, Schuler, Franz, Rogers-Evans, Mark, Müller, Klaus

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