A Calcium Guard in the Outer Membrane: Is VDAC a Regulated Gatekeeper of Mitochondrial Calcium Uptake? von Sander, Paulina, Gudermann, Thomas, Schredelseker, Johann

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Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function von Gerndt, Susanne, Chen, Cheng-Chang, Chao, Yu-Kai, Yuan, Yu, Burgstaller, Sandra, Rosato, Anna Scotto, Krogsaeter, Einar, Urban, Nicole, Jacob, Katharina, Ong Nam Phuong Nguyen, Miller, Meghan T., Keller, Marco, Vollmar, Angelika M., Gudermann, Thomas, Zierler, Susanna, Schredelseker, Johann, Schaefer, Michael, Biel, Martin, Malli, Roland, Wahl-Schott, Christian, Bracher, Franz, Patel, Sandip, Grimm, Christian

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E as in Enigma: The Mysterious Role of the Voltage-Dependent Anion Channel Glutamate E73 von Rister, Alexander Bernhard, Gudermann, Thomas, Schredelseker, Johann

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Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal von Baumann, Tobias, Dunkel, Andreas, Schmid, Christian, Schmitt, Sabine, Hiltensperger, Michael, Lohr, Kerstin, Laketa, Vibor, Donakonda, Sainitin, Ahting, Uwe, Lorenz-Depiereux, Bettina, Heil, Jan E., Schredelseker, Johann, Simeoni, Luca, Fecher, Caroline, Körber, Nina, Bauer, Tanja, Hüser, Norbert, Hartmann, Daniel, Laschinger, Melanie, Eyerich, Kilian, Eyerich, Stefanie, Anton, Martina, Streeter, Matthew, Wang, Tina, Schraven, Burkhart, Spiegel, David, Assaad, Farhah, Misgeld, Thomas, Zischka, Hans, Murray, Peter J., Heine, Annkristin, Heikenwälder, Mathias, Korn, Thomas, Dawid, Corinna, Hofmann, Thomas, Knolle, Percy A., Höchst, Bastian

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TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP von Ferioli, Silvia, Zierler, Susanna, Zaißerer, Joanna, Schredelseker, Johann, Gudermann, Thomas, Chubanov, Vladimir

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High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population von Schredelseker, Johann, Paz, Aviv, López, Carlos J., Altenbach, Christian, Leung, Calvin S., Drexler, Maria K., Chen, Jau-Nian, Hubbell, Wayne L., Abramson, Jeff

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Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis von Sander, Paulina, Feng, Michael, Schweitzer, Maria K., Wilting, Fabiola, Gutenthaler, Sophie M., Arduino, Daniela M., Fischbach, Sandra, Dreizehnter, Lisa, Moretti, Alessandra, Gudermann, Thomas, Perocchi, Fabiana, Schredelseker, Johann

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Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis von Shankar, Thirupura S., Ramadurai, Dinesh K. A., Steinhorst, Kira, Sommakia, Salah, Badolia, Rachit, Thodou Krokidi, Aspasia, Calder, Dallen, Navankasattusas, Sutip, Sander, Paulina, Kwon, Oh Sung, Aravamudhan, Aishwarya, Ling, Jing, Dendorfer, Andreas, Xie, Changmin, Kwon, Ohyun, Cheng, Emily H. Y., Whitehead, Kevin J., Gudermann, Thomas, Richardson, Russel S., Sachse, Frank B., Schredelseker, Johann, Spitzer, Kenneth W., Chaudhuri, Dipayan, Drakos, Stavros G.

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Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity von Shimizu, Hirohito, Schredelseker, Johann, Huang, Jie, Lu, Kui, Naghdi, Shamim, Lu, Fei, Franklin, Sarah, Fiji, Hannah DG, Wang, Kevin, Zhu, Huanqi, Tian, Cheng, Lin, Billy, Nakano, Haruko, Ehrlich, Amy, Nakai, Junichi, Stieg, Adam Z, Gimzewski, James K, Nakano, Atsushi, Goldhaber, Joshua I, Vondriska, Thomas M, Hajnóczky, György, Kwon, Ohyun, Chen, Jau-Nian

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Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction von Sierra-Marquez, Juan, Schaller, Lena, Sassenbach, Lukas, Ramírez-Fernández, Antonio, Alt, Philipp, Rissiek, Björn, Zimmer, Béla, Schredelseker, Johann, Hector, Julia, Stähler, Tobias, Koch-Nolte, Friedrich, Staab-Weijnitz, Claudia A, Dietrich, Alexander, Kopp, Robin, Nicke, Annette

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TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema von Weber, Jonas, Rajan, Suhasini, Schremmer, Christian, Chao, Yu-Kai, Krasteva-Christ, Gabriela, Kannler, Martina, Yildirim, Ali Onder, Brosien, Monika, Schredelseker, Johann, Weissmann, Norbert, Grimm, Christian, Gudermann, Thomas, Dietrich, Alexander

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Non-Ca²⁺-conducting Ca²⁺ channels in fish skeletal muscle excitation-contraction coupling von Schredelseker, Johann, Shrivastav, Manisha, Dayal, Anamika, Grabner, Manfred

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Glutamate 73 Promotes Anti-arrhythmic Effects of Voltage-Dependent Anion Channel Through Regulation of Mitochondrial Ca2+ Uptake von Shimizu, Hirohito, Huber, Simon, Langenbacher, Adam D., Crisman, Lauren, Huang, Jie, Wang, Kevin, Wilting, Fabiola, Gudermann, Thomas, Schredelseker, Johann, Chen, Jau-Nian

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The β1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle von Schredelseker, Johann, Di Biase, Valentina, Obermair, Gerald J., Felder, E. Tatiana, Flucher, Bernhard E., Franzini-Armstrong, Clara, Grabner, Manfred

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Abstract P401: The Anti-arrhythmic Effects Of VDAC Isoforms Are Mediated By Glutamate 73 Through Regulation Of Mitochondrial Calcium Transport von Crisman, Lauren, Shimizu, Hirohito, Langenbacher, Adam, Huang, Jie, Wang, Kevin, Schredelseker, Johann, Chen, Jau-Nian

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Proper Restoration of Excitation-Contraction Coupling in the Dihydropyridine Receptor β1-null Zebrafish Relaxed Is an Exclusive Function of the β1a Subunit von Schredelseker, Johann, Dayal, Anamika, Schwerte, Thorsten, Franzini-Armstrong, Clara, Grabner, Manfred

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Novel Mitochondrial Ca2+ Uptake Enhancers for the Treatment of Cardiac Arrhythmia von Sander, Paulina, Arduino, Daniela M., Schweitzer, Maria K., Wilting, Fabiola, Gudermann, Thomas, Perocchi, Fabiana, Schredelseker, Johann

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The antiarrhythmic compound efsevin directly modulates voltage‐dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake von Wilting, Fabiola, Kopp, Robin, Gurnev, Philip A., Schedel, Anna, Dupper, Nathan J., Kwon, Ohyun, Nicke, Annette, Gudermann, Thomas, Schredelseker, Johann

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Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models von Schweitzer, Maria K., MSc, Wilting, Fabiola, MSc, Sedej, Simon, PhD, Dreizehnter, Lisa, PhD, Dupper, Nathan J., BSc, Tian, Qinghai, PhD, Moretti, Alessandra, PhD, My, Ilaria, MD, Kwon, Ohyun, PhD, Priori, Silvia G., MD, PhD, Laugwitz, Karl-Ludwig, MD, Storch, Ursula, PhD, Lipp, Peter, PhD, Breit, Andreas, PhD, Mederos y Schnitzler, Michael, PhD, Gudermann, Thomas, MD, Schredelseker, Johann, PhD

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Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling von Breit, Andreas, Miek, Laura, Schredelseker, Johann, Geibel, Mirjam, Merrow, Martha, Gudermann, Thomas

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