The experimental power of FR900359 to study Gq-regulated biological processes von Schrage, Ramona, Schmitz, Anna-Lena, Gaffal, Evelyn, Annala, Suvi, Kehraus, Stefan, Wenzel, Daniela, Büllesbach, Katrin M., Bald, Tobias, Inoue, Asuka, Shinjo, Yuji, Galandrin, Ségolène, Shridhar, Naveen, Hesse, Michael, Grundmann, Manuel, Merten, Nicole, Charpentier, Thomas H., Martz, Matthew, Butcher, Adrian J., Slodczyk, Tanja, Armando, Sylvain, Effern, Maike, Namkung, Yoon, Jenkins, Laura, Horn, Velten, Stößel, Anne, Dargatz, Harald, Tietze, Daniel, Imhof, Diana, Galés, Céline, Drewke, Christel, Müller, Christa E., Hölzel, Michael, Milligan, Graeme, Tobin, Andrew B., Gomeza, Jesús, Dohlman, Henrik G., Sondek, John, Harden, T. Kendall, Bouvier, Michel, Laporte, Stéphane A., Aoki, Junken, Fleischmann, Bernd K., Mohr, Klaus, König, Gabriele M., Tüting, Thomas, Kostenis, Evi

Volltext

A Perfused In Vitro Human iPSC-Derived Blood–Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies von Burgio, Floriana, Gaiser, Carine, Brady, Kevin, Gatta, Viviana, Class, Reiner, Schrage, Ramona, Suter-Dick, Laura

Volltext

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells von Annala Suvi, Feng Xiaodong, Shridhar Naveen, Eryilmaz Funda, Patt, Julian, Yang JuHee, Pfeil, Eva M, Cervantes-Villagrana Rodolfo Daniel, Inoue Asuka, Häberlein Felix, Slodczyk Tanja, Reher Raphael, Kehraus Stefan, Monteleone Stefania, Schrage Ramona, Heycke Nina, Rick, Ulrike, Engel, Sandra, Pfeifer, Alexander, Kolb, Peter, König Gabriele, Bünemann Moritz, Tüting, Thomas, Vázquez-Prado José, Silvio, Gutkind J, Gaffal Evelyn, Kostenis Evi

Volltext

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling von Bock, Andreas, Merten, Nicole, Schrage, Ramona, Dallanoce, Clelia, Bätz, Julia, Klöckner, Jessica, Schmitz, Jens, Matera, Carlo, Simon, Katharina, Kebig, Anna, Peters, Lucas, Müller, Anke, Schrobang-Ley, Jasmin, Tränkle, Christian, Hoffmann, Carsten, De Amici, Marco, Holzgrabe, Ulrike, Kostenis, Evi, Mohr, Klaus

Volltext

Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation von Merten, Nicole, Fischer, Julia, Simon, Katharina, Zhang, Liguo, Schröder, Ralf, Peters, Lucas, Letombe, Anne-Gaelle, Hennen, Stephanie, Schrage, Ramona, Bödefeld, Theresa, Vermeiren, Celine, Gillard, Michel, Mohr, Klaus, Lu, Qing Richard, Brüstle, Oliver, Gomeza, Jesus, Kostenis, Evi

Volltext

Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor von Chen, Xinyu, Klöckner, Jessika, Holze, Janine, Zimmermann, Cornelia, Seemann, Wiebke K, Schrage, Ramona, Bock, Andreas, Mohr, Klaus, Tränkle, Christian, Holzgrabe, Ulrike, Decker, Michael

Volltext

Allosteric modulators targeting CNS muscarinic receptors von Bock, Andreas, Schrage, Ramona, Mohr, Klaus

Volltext

Functional selectivity and dualsteric/bitopic GPCR targeting von Schrage, Ramona, Kostenis, Evi

Volltext

Ligand-Specific Allosteric Coupling Controls G‑Protein-Coupled Receptor Signaling von Holze, Janine, Bermudez, Marcel, Pfeil, Eva Marie, Kauk, Michael, Bödefeld, Theresa, Irmen, Matthias, Matera, Carlo, Dallanoce, Clelia, De Amici, Marco, Holzgrabe, Ulrike, König, Gabriele Maria, Tränkle, Christian, Wolber, Gerhard, Schrage, Ramona, Mohr, Klaus, Hoffmann, Carsten, Kostenis, Evi, Bock, Andreas

Volltext

Molecular Alliance-From Orthosteric and Allosteric Ligands to Dualsteric/Bitopic Agonists at G Protein Coupled Receptors von Mohr, Klaus, Schmitz, Jens, Schrage, Ramona, Tränkle, Christian, Holzgrabe, Ulrike

Volltext

Direct targeting of Gα q and Gα 11 oncoproteins in cancer cells von Annala, Suvi, Feng, Xiaodong, Shridhar, Naveen, Eryilmaz, Funda, Patt, Julian, Yang, JuHee, Pfeil, Eva M, Cervantes-Villagrana, Rodolfo Daniel, Inoue, Asuka, Häberlein, Felix, Slodczyk, Tanja, Reher, Raphael, Kehraus, Stefan, Monteleone, Stefania, Schrage, Ramona, Heycke, Nina, Rick, Ulrike, Engel, Sandra, Pfeifer, Alexander, Kolb, Peter, König, Gabriele, Bünemann, Moritz, Tüting, Thomas, Vázquez-Prado, José, Gutkind, J Silvio, Gaffal, Evelyn, Kostenis, Evi

Volltext

Humanized zebrafish as a tractable tool for in vivo evaluation of pro-myelinating drugs von Häberlein, Felix, Mingardo, Enrico, Merten, Nicole, Schulze Köhling, Nina-Katharina, Reinoß, Philip, Simon, Katharina, Japp, Anna, Nagarajan, Bhuvaneswari, Schrage, Ramona, Pegurier, Cecile, Gillard, Michel, Monk, Kelly R., Odermatt, Benjamin, Kostenis, Evi, Gomeza, Jesus

Volltext

Rational Design of Partial Agonists for the Muscarinic M 1 Acetylcholine Receptor von Chen, Xinyu, Klöckner, Jessika, Holze, Janine, Zimmermann, Cornelia, Seemann, Wiebke K., Schrage, Ramona, Bock, Andreas, Mohr, Klaus, Tränkle, Christian, Holzgrabe, Ulrike, Decker, Michael

Volltext

Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist von Hennen, Stephanie, Wang, Haibo, Peters, Lucas, Merten, Nicole, Simon, Katharina, Spinrath, Andreas, Blättermann, Stefanie, Akkari, Rhalid, Schrage, Ramona, Schröder, Ralf, Schulz, Daniel, Vermeiren, Celine, Zimmermann, Katrin, Kehraus, Stefan, Drewke, Christel, Pfeifer, Alexander, König, Gabriele M, Mohr, Klaus, Gillard, Michel, Müller, Christa E, Lu, Q Richard, Gomeza, Jesus, Kostenis, Evi

Volltext

The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes von Simon, Katharina, Merten, Nicole, Schröder, Ralf, Hennen, Stephanie, Preis, Philip, Schmitt, Nina-Katharina, Peters, Lucas, Schrage, Ramona, Vermeiren, Celine, Gillard, Michel, Mohr, Klaus, Gomeza, Jesus, Kostenis, Evi

Volltext

Dualsteric Muscarinic Antagonists–Orthosteric Binding Pose Controls Allosteric Subtype Selectivity von Schmitz, Jens, van der Mey, Dorina, Bermudez, Marcel, Klöckner, Jessica, Schrage, Ramona, Kostenis, Evi, Tränkle, Christian, Wolber, Gerhard, Mohr, Klaus, Holzgrabe, Ulrike

Volltext

A New Molecular Mechanism To Engineer Protean Agonism at a G Protein–Coupled Receptor von De Min, Anna, Matera, Carlo, Bock, Andreas, Holze, Janine, Kloeckner, Jessica, Muth, Mathias, Traenkle, Christian, De Amici, Marco, Kenakin, Terry, Holzgrabe, Ulrike, Dallanoce, Clelia, Kostenis, Evi, Mohr, Klaus, Schrage, Ramona

Volltext

New insight into active muscarinic receptors with the novel radioagonist [3H]iperoxo von Schrage, Ramona, Holze, Janine, Klöckner, Jessica, Balkow, Aileen, Klause, Anne S., Schmitz, Anna-Lena, De Amici, Marco, Kostenis, Evi, Tränkle, Christian, Holzgrabe, Ulrike, Mohr, Klaus

Volltext

Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor von Seemann, Wiebke K., Wenzel, Daniela, Schrage, Ramona, Etscheid, Justine, Bödefeld, Theresa, Bartol, Anna, Warnken, Mareille, Sasse, Philipp, Klöckner, Jessica, Holzgrabe, Ulrike, DeAmici, Marco, Schlicker, Eberhard, Racké, Kurt, Kostenis, Evi, Meyer, Rainer, Fleischmann, Bernd K., Mohr, Klaus

Volltext

Molecular Alliance--From Orthosteric and Allosteric Ligands to Dualsteric/Bitopic Agonists at GProtein Coupled Receptors von Mohr, Klaus, Schmitz, Jens, Schrage, Ramona, Tränkle, Christian, Holzgrabe, Ulrike

Volltext