Formation and Signaling Actions of Electrophilic Lipids von Schopfer, Francisco J, Cipollina, Chiara, Freeman, Bruce A

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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling von Hansen, Anne Louise, Buchan, Gregory J., Rühl, Michael, Mukai, Kojiro, Salvatore, Sonia R., Ogawa, Emari, Andersen, Sidsel D., Iversen, Marie B., Thielke, Anne L., Gunderstofte, Camilla, Motwani, Mona, Møller, Charlotte T., Jakobsen, Andreas S., Fitzgerald, Katherine A., Roos, Jessica, Lin, Rongtuan, Maier, Thorsten J., Goldbach-Mansky, Raphaela, Miner, Cathrine A., Qian, Wei, Miner, Jonathan J., Rigby, Rachel E., Rehwinkel, Jan, Jakobsen, Martin R., Arai, Hiroyuki, Taguchi, Tomohiko, Schopfer, Francisco J., Olagnier, David, Holm, Christian K.

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Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases von Schopfer, Francisco J., Vitturi, Dario A., Jorkasky, Diane K., Freeman, Bruce A.

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Olives and olive oil are sources of electrophilic fatty acid nitroalkenes von Fazzari, Marco, Trostchansky, Andrés, Schopfer, Francisco J, Salvatore, Sonia R, Sánchez-Calvo, Beatriz, Vitturi, Dario, Valderrama, Raquel, Barroso, Juan B, Radi, Rafael, Freeman, Bruce A, Rubbo, Homero

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Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling von Rahaman, Mizanur M, Nguyen, Anh T, Miller, Megan P, Hahn, Scott A, Sparacino-Watkins, Courtney, Jobbagy, Soma, Carew, Nolan T, Cantu-Medellin, Nadiezhda, Wood, Katherine C, Baty, Catherine J, Schopfer, Francisco J, Kelley, Eric E, Gladwin, Mark T, Martin, Emil, Straub, Adam C

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Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism von Kansanen, Emilia, Bonacci, Gustavo, Schopfer, Francisco J., Kuosmanen, Suvi M., Tong, Kit I., Leinonen, Hanna, Woodcock, Steven R., Yamamoto, Masayuki, Carlberg, Carsten, Ylä-Herttuala, Seppo, Freeman, Bruce A., Levonen, Anna-Liisa

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Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids[S] von Fazzari, Marco, Vitturi, Dario A., Woodcock, Steven R., Salvatore, Sonia R., Freeman, Bruce A., Schopfer, Francisco J.

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Nitrolinoleic Acid: An Endogenous Peroxisome Proliferator-Activated Receptor γ Ligand von Schopfer, Francisco J., Lin, Yiming, Paul R. S. Baker, Cui, Taixing, Garcia-Barrio, Minerva, Zhang, Jifeng, Chen, Kai, Chen, Yuqing E., Freeman, Bruce A., Ignarro, Louis J.

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Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death von Carew, Nolan T, Schmidt, Heidi M, Yuan, Shuai, Galley, Joseph C, Hall, Robert, Altmann, Helene M, Hahn, Scott A, Miller, Megan P, Wood, Katherine C, Gabris, Bethann, Stapleton, Margaret C, Hartwick, Sean, Fazzari, Marco, Wu, Yijen L, Trebak, Mohamed, Kaufman, Brett A, McTiernan, Charles F, Schopfer, Francisco J, Navas, Placido, Thibodeau, Patrick H, McNamara, Dennis M, Salama, Guy, Straub, Adam C

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Conjugated Linoleic Acid Is a Preferential Substrate for Fatty Acid Nitration von Bonacci, Gustavo, Baker, Paul R.S., Salvatore, Sonia R., Shores, Darla, Khoo, Nicholas K.H., Koenitzer, Jeffrey R., Vitturi, Dario A., Woodcock, Steven R., Golin-Bisello, Franca, Cole, Marsha P., Watkins, Simon, St. Croix, Claudette, Batthyany, Carlos I., Freeman, Bruce A., Schopfer, Francisco J.

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Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives von Cipollina, Chiara, Salvatore, Sonia R, Muldoon, Matthew F, Freeman, Bruce A, Schopfer, Francisco J

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Nitro-fatty acid pharmacokinetics in the adipose tissue compartment von Fazzari, Marco, Khoo, NicholasK.H., Woodcock, Steven R., Jorkasky, Diane K., Li, Lihua, Schopfer, Francisco J., Freeman, Bruce A.

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Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride von Vitturi, Dario A, Minarrieta, Lucia, Salvatore, Sonia R, Postlethwait, Edward M, Fazzari, Marco, Ferrer-Sueta, Gerardo, Lancaster, Jack R, Freeman, Bruce A, Schopfer, Francisco J

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Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion von Rudolph, Volker, Rudolph, Tanja K., Schopfer, Francisco J., Bonacci, Gustavo, Woodcock, Steven R., Cole, Marsha P., Baker, Paul R.S., Ramani, Ravi, Freeman, Bruce A.

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Evaluation of 10-Nitro Oleic Acid Bio-Elimination in Rats and Humans von Salvatore, Sonia R., Vitturi, Dario A., Fazzari, Marco, Jorkasky, Diane K., Schopfer, Francisco J.

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Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis von Perez-Rosello, Tamara, Anderson, Charles T, Schopfer, Francisco J, Zhao, Yanjun, Gilad, David, Salvatore, Sonia R, Freeman, Bruce A, Hershfinkel, Michal, Aizenman, Elias, Tzounopoulos, Thanos

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Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages von Vazquez, Matias M., Gutierrez, Maria V., Salvatore, Sonia R., Puiatti, Marcelo, Dato, Virginia Actis, Chiabrando, Gustavo A., Freeman, Bruce A., Schopfer, Francisco J., Bonacci, Gustavo

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Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators von Cui, Taixing, Schopfer, Francisco J., Zhang, Jifeng, Chen, Kai, Ichikawa, Tomonaga, Baker Paul, R.S., Batthyany, Carlos, Chacko, Balu K., Feng, Xu, Patel, Rakesh P., Agarwal, Anupam, Freeman, Bruce A., Chen, Yuqing E.

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Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine[S] von Salvatore, Sonia R., Vitturi, Dario A., Baker, Paul R.S., Bonacci, Gustavo, Koenitzer, Jeffrey R., Woodcock, Steven R., Freeman, Bruce A., Schopfer, Francisco J.

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In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation von Villacorta, Luis, Minarrieta, Lucia, Salvatore, Sonia R., Khoo, Nicholas K., Rom, Oren, Gao, Zhen, Berman, Rebecca C., Jobbagy, Soma, Li, Lihua, Woodcock, Steven R., Chen, Y. Eugene, Freeman, Bruce A., Ferreira, Ana M., Schopfer, Francisco J., Vitturi, Dario A.

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