Cyclin-Dependent Kinase Inhibitor Dinaciclib Interacts with the Acetyl-Lysine Recognition Site of Bromodomains von Martin, Mathew P, Olesen, Sanne H, Georg, Gunda I, Schönbrunn, Ernst

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Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors von Ember, Stuart W. J, Zhu, Jin-Yi, Olesen, Sanne H, Martin, Mathew P, Becker, Andreas, Berndt, Norbert, Georg, Gunda I, Schönbrunn, Ernst

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Molecular basis for the herbicide resistance of Roundup Ready crops von Funke, T, Han, H, Healy-Fried, M.L, Fischer, M, Schönbrunn, E

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RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer von PATEL, Ronil A, FORINASH, Kara D, PIREDDU, Roberta, YING SUN, NAN SUN, MARTIN, Mathew P, SCHÖNBRUNN, Ernst, LAWRENCE, Nicholas J, SEBTI, Saïd M

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Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX von Phan, Jason, Li, Zhenyu, Kasprzak, Agnieszka, Li, Baozong, Sebti, Said, Guida, Wayne, Schönbrunn, Ernst, Chen, Jiandong

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Discovery of a Potential Allosteric Ligand Binding Site in CDK2 von Betzi, Stephane, Alam, Riazul, Martin, Mathew, Lubbers, Donna J, Han, Huijong, Jakkaraj, Sudhakar R, Georg, Gunda I, Schönbrunn, Ernst

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BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen von Ayoub, Alex M, Hawk, Laura M. L, Herzig, Ryan J, Jiang, Jiewei, Wisniewski, Andrea J, Gee, Clifford T, Zhao, Peiliang, Zhu, Jin-Yi, Berndt, Norbert, Offei-Addo, Nana K, Scott, Thomas G, Qi, Jun, Bradner, James E, Ward, Timothy R, Schönbrunn, Ernst, Georg, Gunda I, Pomerantz, William C. K

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Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA) von Zhu, Jin-Yi, Yang, Yan, Han, Huijong, Betzi, Stephane, Olesen, Sanne H., Marsilio, Frank, Schönbrunn, Ernst

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A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2 von Martin, Mathew P., Alam, Riazul, Betzi, Stephane, Ingles, Donna J., Zhu, Jin-Yi, Schönbrunn, Ernst

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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation von Mahajan, Kiran, Coppola, Domenico, Challa, Sridevi, Fang, Bin, Chen, Y Ann, Zhu, Weiwei, Lopez, Alexis S, Koomen, John, Engelman, Robert W, Rivera, Charlene, Muraoka-Cook, Rebecca S, Cheng, Jin Q, Schönbrunn, Ernst, Sebti, Said M, Earp, H Shelton, Mahajan, Nupam P

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Synthesis and Evaluation of Eight- and Four-Membered Iminosugar Analogues as Inhibitors of Testicular Ceramide-Specific Glucosyltransferase, Testicular β-Glucosidase 2, and Other G... von Lee, Jae Chul, Francis, Subhashree, Dutta, Dinah, Gupta, Vijayalaxmi, Yang, Yan, Zhu, Jin-Yi, Tash, Joseph S, Schönbrunn, Ernst, Georg, Gunda I

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Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin von Olesen, Sanne H., Ingles, Donna J., Yang, Yan, Schönbrunn, Ernst

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A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A von Martin, Mathew P, Zhu, Jin-Yi, Lawrence, Harshani R, Pireddu, Roberta, Luo, Yunting, Alam, Riazul, Ozcan, Sevil, Sebti, Said M, Lawrence, Nicholas J, Schönbrunn, Ernst

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Structural Characterization of the Hemophore HasAp from Pseudomonas aeruginosa: NMR Spectroscopy Reveals Protein−Protein Interactions between Holo-HasAp and Hemoglobin von Alontaga, Aileen Y, Rodriguez, Juan Carlos, Schönbrunn, Ernst, Becker, Andreas, Funke, Todd, Yukl, Erik T, Hayashi, Takahiro, Stobaugh, Jordan, Moënne-Loccoz, Pierre, Rivera, Mario

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Biochemical and Structural Characterization of Pseudomonas aeruginosa Bfd and FPR:  Ferredoxin NADP+ Reductase and Not Ferredoxin Is the Redox Partner of Heme Oxygenase under Iron-... von Wang, An, Zeng, Yuhong, Han, Huijong, Weeratunga, Saroja, Morgan, Bailey N., Moënne-Loccoz, Pierre, Schönbrunn, Ernst, Rivera, Mario

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MurA as a Primary Target of Tulipalin B and 6-Tuliposide B von SHIGETOMI, Kengo, OLESEN, Sanne Harder, YANG, Yan, MITSUHASHI, Shinya, SCHÖNBRUNN, Ernst, UBUKATA, Makoto

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Differential Inhibition of Class I and Class II 5-Enolpyruvylshikimate-3-phosphate Synthases by Tetrahedral Reaction Intermediate Analogues von Funke, Todd, Healy-Fried, Martha L, Han, Huijong, Alberg, David G, Bartlett, Paul A, Schönbrunn, Ernst

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Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2) von Pireddu, Roberta, Forinash, Kara D, Sun, Nan N, Martin, Mathew P, Sung, Shen-Shu, Alexander, Brian, Zhu, Jin-Yi, Guida, Wayne C, Schönbrunn, Ernst, Sebti, Saïd M, Lawrence, Nicholas J

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A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) von Eschenburg, Susanne, Priestman, Melanie A., Abdul-Latif, Farid A., Delachaume, Carole, Fassy, Florence, Schönbrunn, Ernst

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Evidence That the Fosfomycin Target Cys super(115) in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) Is Essential for Product Release von Eschenburg, Susanne, Priestman, Melanie, Schoenbrunn, Ernst

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