Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics von Schmid, Cullen L., Kennedy, Nicole M., Ross, Nicolette C., Lovell, Kimberly M., Yue, Zhizhou, Morgenweck, Jenny, Cameron, Michael D., Bannister, Thomas D., Bohn, Laura M.

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Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria von Brust, Tarsis F, Morgenweck, Jenny, Kim, Susy A, Rose, Jamie H, Locke, Jason L, Schmid, Cullen L, Zhou, Lei, Stahl, Edward L, Cameron, Michael D, Scarry, Sarah M, Aubé, Jeffrey, Jones, Sara R, Martin, Thomas J, Bohn, Laura M

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Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo von Schmid, Cullen L, Raehal, Kirsten M, Bohn, Laura M

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Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain von Pantouli, Fani, Grim, Travis W., Schmid, Cullen L., Acevedo-Canabal, Agnes, Kennedy, Nicole M., Cameron, Michael D., Bannister, Thomas D., Bohn, Laura M.

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Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors von Zhou, Lei, Lovell, Kimberly M., Frankowski, Kevin J., Slauson, Stephen R., Phillips, Angela M., Streicher, John M., Stahl, Edward, Schmid, Cullen L., Hodder, Peter, Madoux, Franck, Cameron, Michael D., Prisinzano, Thomas E., Aubé, Jeffrey, Bohn, Laura M.

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Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine von Acevedo-Canabal, Agnes, Grim, Travis W, Schmid, Cullen L, McFague, Nina, Stahl, Edward L, Kennedy, Nicole M, Bannister, Thomas D, Bohn, Laura M

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Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ‑OR Agonist von Roach, Jeremy J, Sasano, Yusuke, Schmid, Cullen L, Zaidi, Saheem, Katritch, Vsevolod, Stevens, Raymond C, Bohn, Laura M, Shenvi, Ryan A

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Serotonin, But Not N -Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo von Schmid, Cullen L., Bohn, Laura M.

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Functional Selectivity at the μ-Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance von Raehal, Kirsten M., Schmid, Cullen L., Groer, Chad E., Bohn, Laura M.

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Lubiprostone Reverses the Inhibitory Action of Morphine on Intestinal Secretion in Guinea Pig and Mouse von Fei, Guijun, Raehal, Kirsten, Liu, Sumei, Qu, Mei-Hua, Sun, Xiaohong, Wang, Guo-Du, Wang, Xi-Yu, Xia, Yun, Schmid, Cullen L., Bohn, Laura M., Wood, Jackie D.

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G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists von Stahl, Edward L., Schmid, Cullen L., Acevedo-Canabal, Agnes, Read, Cai, Grim, Travis W., Kennedy, Nicole M., Bannister, Thomas D., Bohn, Laura M.

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A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal von Grim, Travis W, Schmid, Cullen L, Stahl, Edward L, Pantouli, Fani, Ho, Jo-Hao, Acevedo-Canabal, Agnes, Kennedy, Nicole M, Cameron, Michael D, Bannister, Thomas D, Bohn, Laura M

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Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation von Groer, Chad E., Schmid, Cullen L., Jaeger, Alex M., Bohn, Laura M.

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Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias von Kennedy, Nicole M, Schmid, Cullen L, Ross, Nicolette C, Lovell, Kimberly M, Yue, Zhizhou, Chen, Yen Ting, Cameron, Michael D, Bohn, Laura M, Bannister, Thomas D

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Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6 von Raehal, Kirsten M, Schmid, Cullen L, Medvedev, Ivan O, Gainetdinov, Raul R, Premont, Richard T, Bohn, Laura M

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Intermolecular Interactions between Retroviral Gag Proteins in the Nucleus von Kenney, Scott P, Lochmann, Timothy L, Schmid, Cullen L, Parent, Leslie J

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Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization von Green, Jill A., Schmid, Cullen L., Bley, Elizabeth, Monsma, Paula C., Brown, Anthony, Bohn, Laura M., Mykytyn, Kirk

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Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt von SCHMID, Cullen L, STREICHER, John M, MELTZER, Herbert Y, BOHN, Laura M

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G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons von Ho, Jo-Hao, Stahl, Edward L, Schmid, Cullen L, Scarry, Sarah M, Aubé, Jeffrey, Bohn, Laura M

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Irreversible and noncompetitive mu opioid receptor agonists von Stahl, Edward, Schmid, Cullen L., Acevedo‐Canabal, Agnes, Read, Cai, Grim, Travis, Kennedy, Nicole M., Bannister, Thomas D., Bohn, Laura M.

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