Biotransformation enzymes in development of renal injury and urothelial cancer caused by aristolochic acid von Stiborová, M., Frei, E., Schmeiser, H.H.

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Chemical and molecular basis of Aristolochia and other herbal toxicities von Schmeiser, H.H

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Mycotoxin ochratoxin A decreases cytochrome P450-mediated detoxication of carcinogenic aristolochic acid thereby increases its genotoxic potential in rats in vivo von Barta, F., Levova, K., Hodek, P., Frei, E., Arlt, V.M., Schmeiser, H.H., Stiborova, M.

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NADPH- and NADH-dependent formation of DNA adducts by benzo[a]pyrene catalyzed with cytochrome P450 1A1 von Moserova, M., Indra, R., Milichovsky, J., Frei, E., Schmeiser, H.H., Arlt, V.M., Stiborova, M.

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Treatment with a mixture of aristolochic acid I and II influences their genotoxicity and expression of biotransformation enzymes in rats in vivo von Stiborova, M., Barta, F., Dracinska, H., Hudecova, A., Hodek, P., Balogova, M., Mraz, J., Duskova, S., Schmeiser, H.H., Arlt, V.M.

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Genotoxicity of aristolochia plants von Schmeiser, H.H., Stiborova, M., Arlt, V.M.

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Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences von Feldmeyer, N., Schmeiser, H.H., Muehlbauer, K.-R., Belharazem, D., Knyazev, Y., Nedelko, T., Hollstein, M.

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Activating mutations at codon 61 of the c-Ha- ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice von Schmeiser, H.H., Scherf, H.R., Wiessler, M.

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DNA adduct formation of aristolochic acid I and II in vitro and in vivo von Schmeiser, H.H., Schoepe, K.-B., Wiessler, M.

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Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver von Schmeiser, H.H., Pool, B.L., Wiessler, M.

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Mutagenicity of the two main components of commercially available carcinogenic aristolochic acid in Salmonella typhimurium von Schmeiser, H.H., Pool, B.L., Wiessler, M.

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Oxidation of xenobiotics by plant microsomes, a reconstituted cytochrome P450 system and peroxidase: a comparative study von Stiborová, M, Schmeiser, H.H, Frei, E

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Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy von Stiborová, M., Frei, E., Breuer, A., Bieler, C.A., Schmeiser, H.H.

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Mechanism of formation and 32P-postlabeling of DNA adducts derived from peroxidative activation of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I) von Stiborová, M., Frei, E., Schmeiser, H.H., Hradec, J.

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Mechanism of formation and 32 P-postlabeling of DNA adducts derived from peroxidative activation of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I) von Stiborová, M., Frei, E., Schmeiser, H.H., Hradec, J.

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Mutagenicity and in vitro metabolism of aristolochic acid von Schmeiser, H.H., Pool, B.L., Wiessler, M.

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